83 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111187648	C-X-C motif chemokine 6-like. (113 aa)
	CCL19	C-C motif chemokine. (159 aa)
	B4GALT1	Beta-1,4-galactosyltransferase 1. (402 aa)
	GP2	Pancreatic secretory granule membrane major glycoprotein GP2. (530 aa)
	UMOD	Uromodulin. (643 aa)
	EPX	Eosinophil peroxidase. (715 aa)
	CCL21	C-C motif chemokine 21 isoform X1. (131 aa)
	LOC111163731	C-C motif chemokine. (93 aa)
	LOC111163732	C-C motif chemokine. (92 aa)
	UMODL1	Uromodulin-like 1. (1321 aa)
	CCL5	C-C motif chemokine. (91 aa)
	LOC111163729	C-C motif chemokine. (194 aa)
	LOC111163733	C-C motif chemokine. (90 aa)
	CCL22	C-C motif chemokine. (93 aa)
	CX3CL1	Fractalkine. (469 aa)
	EMP2	Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
	VAV1	Proto-oncogene vav isoform X1. (845 aa)
	LOC111166483	Signal transducer and activator of transcription. (787 aa)
	CCR7	C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. (379 aa)
	CCL17	C-C motif chemokine. (109 aa)
	JAML	Junctional adhesion molecule-like. (383 aa)
	FCER1G	High affinity immunoglobulin epsilon receptor subunit gamma. (86 aa)
	S100A8	Protein S100; Belongs to the S-100 family. (89 aa)
	XCL1	Lymphotactin. (111 aa)
	LOC111167106	Protein S100-A9-like; Belongs to the S-100 family. (135 aa)
	JAM3	Junctional adhesion molecule C. (301 aa)
	SLC37A4	Glucose-6-phosphate exchanger SLC37A4 isoform X1. (429 aa)
	KIT	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
	SYK	Tyrosine-protein kinase. (626 aa)
	IL17RC	Interleukin-17 receptor C isoform X1. (713 aa)
	JAGN1	Protein jagunal homolog 1. (183 aa)
	CNN2	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (380 aa)
	CCL20	C-C motif chemokine. (97 aa)
	WDR1	WD repeat-containing protein 1. (606 aa)
	LOC111171209	C-C motif chemokine 13-like. (116 aa)
	NCKAP1L	Nck-associated protein 1-like isoform X1. (1156 aa)
	FAM19A4	Protein FAM19A4. (145 aa)
	PIKFYVE	1-phosphatidylinositol 3-phosphate 5-kinase isoform X1. (2110 aa)
	LOC111171817	C-X-C chemokine receptor type 2-like; Belongs to the G-protein coupled receptor 1 family. (368 aa)
	ANXA1	Annexin. (346 aa)
	SCG2	Secretogranin-2. (615 aa)
	IRAK4	Interleukin-1 receptor-associated kinase 4 isoform X1. (460 aa)
	SRP54	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa)
	TNFSF11	Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa)
	CXADR	Coxsackievirus and adenovirus receptor isoform X1. (365 aa)
	FLT1	Vascular endothelial growth factor receptor 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1340 aa)
	EDN2	Endothelin-2. (147 aa)
	LGALS3	Galectin. (256 aa)
	CHGA	chromogranin-A isoform X1. (445 aa)
	EDNRB	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (443 aa)
	CSF3R	Granulocyte colony-stimulating factor receptor isoform X1. (846 aa)
	IL17A	interleukin-17A. (155 aa)
	PTPRO	Receptor-type tyrosine-protein phosphatase O isoform X1. (1216 aa)
	PPIB	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
	MCOLN2	Mucolipin-2 isoform X1. (566 aa)
	VAV3	Guanine nucleotide exchange factor VAV3. (954 aa)
	PDE4B	Phosphodiesterase. (736 aa)
	C5AR1	C5a anaphylatoxin chemotactic receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (424 aa)
	LOC111181112	Uncharacterized protein LOC111181112. (257 aa)
	CSF1	Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (554 aa)
	CCL26	C-C motif chemokine 26. (94 aa)
	LOC111182630	Platelet endothelial cell adhesion molecule-like isoform X2. (305 aa)
	NUP85	Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (656 aa)
	CCL24	C-C motif chemokine 24. (119 aa)
	PECAM1	Platelet endothelial cell adhesion molecule isoform X1. (701 aa)
	LBP	Lipopolysaccharide-binding protein isoform X1. (537 aa)
	PDGFB	Platelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (278 aa)
	LOC111185731	C-C motif chemokine. (99 aa)
	LOC111185794	C-C motif chemokine. (97 aa)
	PAFAH1B1	Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
	BCR	Breakpoint cluster region protein isoform X1. (1275 aa)
	TRIM55	Tripartite motif-containing protein 55 isoform X1. (534 aa)
	NF1	Neurofibromin isoform X1. (2873 aa)
	PREX1	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein isoform X1. (1653 aa)
	PPBP	C-X-C motif chemokine. (119 aa)
	CXCL10	C-X-C motif chemokine. (103 aa)
	LOC111185888	C-C motif chemokine. (99 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	MSMP	Beta-microseminoprotein. (139 aa)
	LOC111187580	C-X-C motif chemokine. (112 aa)
	CXCL11	C-X-C motif chemokine 11. (100 aa)
	ITGA1	Integrin alpha-1; Belongs to the integrin alpha chain family. (1178 aa)
	CXCL13	C-X-C motif chemokine 13. (109 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANXA1	CSF1	A0A2Y9N3F3	A0A2Y9PBL1	Annexin.	Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...]	0.590
ANXA1	LGALS3	A0A2Y9N3F3	A0A2Y9NAF6	Annexin.	Galectin.	0.407
ANXA1	TNFSF11	A0A2Y9N3F3	A0A2Y9N775	Annexin.	Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family.	0.438
BCR	LOC111166483	A0A2Y9LBZ9	A0A2Y9LW55	Breakpoint cluster region protein isoform X1.	Signal transducer and activator of transcription.	0.911
CCL17	CCL19	A0A2Y9LX78	A0A2Y9LCM2	C-C motif chemokine.	C-C motif chemokine.	0.514
CCL17	CCL20	A0A2Y9LX78	A0A2Y9MNZ7	C-C motif chemokine.	C-C motif chemokine.	0.629
CCL17	CCL21	A0A2Y9LX78	A0A2Y9LF88	C-C motif chemokine.	C-C motif chemokine 21 isoform X1.	0.960
CCL17	CCL22	A0A2Y9LX78	A0A2Y9LQD0	C-C motif chemokine.	C-C motif chemokine.	0.982
CCL17	CCL24	A0A2Y9LX78	A0A2Y9PNJ2	C-C motif chemokine.	C-C motif chemokine 24.	0.682
CCL17	CCL26	A0A2Y9LX78	A0A2Y9PBQ6	C-C motif chemokine.	C-C motif chemokine 26.	0.952
CCL17	CCL5	A0A2Y9LX78	A0A2Y9LMK7	C-C motif chemokine.	C-C motif chemokine.	0.996
CCL17	CCR7	A0A2Y9LX78	A0A2Y9LWJ5	C-C motif chemokine.	C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family.	0.827
CCL17	CSF1	A0A2Y9LX78	A0A2Y9PBL1	C-C motif chemokine.	Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...]	0.448
CCL17	CX3CL1	A0A2Y9LX78	A0A2Y9LQH9	C-C motif chemokine.	Fractalkine.	0.492
CCL17	CXCL10	A0A2Y9LX78	A0A2Y9Q7R7	C-C motif chemokine.	C-X-C motif chemokine.	0.728
CCL17	CXCL11	A0A2Y9LX78	A0A2Y9QCF8	C-C motif chemokine.	C-X-C motif chemokine 11.	0.671
CCL17	CXCL13	A0A2Y9LX78	A0A2Y9QI31	C-C motif chemokine.	C-X-C motif chemokine 13.	0.671
CCL17	IL17A	A0A2Y9LX78	A0A2Y9NPV8	C-C motif chemokine.	interleukin-17A.	0.463
CCL17	LOC111163731	A0A2Y9LX78	A0A2Y9LFN9	C-C motif chemokine.	C-C motif chemokine.	0.656
CCL17	LOC111163732	A0A2Y9LX78	A0A2Y9LI15	C-C motif chemokine.	C-C motif chemokine.	0.656