STRINGSTRING
IL23R IL23R CACNG2 CACNG2 TLR2 TLR2 TGFBR1 TGFBR1 GRIN3A GRIN3A STOML2 STOML2 DIABLO DIABLO GABBR2 GABBR2 ITGA1 ITGA1 ITGA2 ITGA2 ITGB2 ITGB2 IGF1R IGF1R SHISA6 SHISA6 LOC111187417 LOC111187417 IL18R1 IL18R1 IL6ST IL6ST CHRNA2 CHRNA2 SHISA8 SHISA8 LOC111186752 LOC111186752 CHRNA4 CHRNA4 ITGAE ITGAE TRAF5 TRAF5 DLG4 DLG4 RAMP3 RAMP3 CSF2RB CSF2RB CD6 CD6 TSPAN32 TSPAN32 CACNG4 CACNG4 VWC2 VWC2 ITGB4 ITGB4 ITGAL ITGAL GRIA1 GRIA1 ITGB8 ITGB8 CACNG5 CACNG5 GRIN2C GRIN2C CSF2 CSF2 CACNG7 CACNG7 CD79B CD79B ITGAM ITGAM SHISA7 SHISA7 CPT1C CPT1C LOC111182106 LOC111182106 ITGB3 ITGB3 OLFM3 OLFM3 CACNG3 CACNG3 TRAF6 TRAF6 TFR2 TFR2 CACNG8 CACNG8 GRIA2 GRIA2 LOC111179199 LOC111179199 HFE2 HFE2 CD79A CD79A CBFB CBFB GRIN2D GRIN2D CHRNA3 CHRNA3 ITGB1 ITGB1 ITGA10 ITGA10 GRIN1 GRIN1 GRID2 GRID2 EPS8 EPS8 ITGA8 ITGA8 GRIN2B GRIN2B TRAF2 TRAF2 CHRNA7 CHRNA7 CHRNA5 CHRNA5 EMILIN1 EMILIN1 ITGA11 ITGA11 PTPN6 PTPN6 CHRNB4 CHRNB4 GRIK3 GRIK3 GNAT1 GNAT1 ACVRL1 ACVRL1 TRAF3 TRAF3 ITGA6 ITGA6 ACVR1B ACVR1B ITGA7 ITGA7 ABHD6 ABHD6 AMHR2 AMHR2 ITGB6 ITGB6 ITGB7 ITGB7 ERBB3 ERBB3 LOC111171171 LOC111171171 CHRNA1 CHRNA1 ACVR1C ACVR1C CHRND CHRND ACVR1 ACVR1 TLR6 TLR6 GRIN3B GRIN3B VWC2L VWC2L ITGAV ITGAV ITGA4 ITGA4 CHRNA9 CHRNA9 LOC111171159 LOC111171159 ITGB5 ITGB5 CALCRL CALCRL DLG3 DLG3 GP9 GP9 SYK SYK ITGA2B ITGA2B GPR156 GPR156 CD40 CD40 GRIA3 GRIA3 PORCN PORCN CD247 CD247 IL6R IL6R HTR3B HTR3B HTRA2 HTRA2 HFE HFE CHRNB2 CHRNB2 GABBR1 GABBR1 STXBP5 STXBP5 GRIA4 GRIA4 ITGA3 ITGA3 ERBB2 ERBB2 GRIK4 GRIK4 INSRR INSRR IL12RB1 IL12RB1 HTR3A HTR3A CD3E CD3E IL27RA IL27RA CD3G CD3G BMP2 BMP2 CD3D CD3D RAMP2 RAMP2 GRM1 GRM1 ACVR2B ACVR2B RNF31 RNF31 INSR INSR ITGA9 ITGA9 GRIK2 GRIK2 GRIN2A GRIN2A SHISA9 SHISA9 IFNLR1 IFNLR1 CNTFR CNTFR GP1BB GP1BB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL23RInterleukin-23 receptor. (630 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
TLR2Toll-like receptor 2; Belongs to the Toll-like receptor family. (785 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
GRIN3AGlutamate receptor ionotropic, NMDA 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1115 aa)
STOML2Stomatin-like protein 2, mitochondrial. (356 aa)
DIABLODiablo homolog, mitochondrial isoform X1. (237 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (941 aa)
ITGA1Integrin alpha-1; Belongs to the integrin alpha chain family. (1178 aa)
ITGA2Integrin alpha-2; Belongs to the integrin alpha chain family. (1179 aa)
ITGB2Integrin beta. (769 aa)
IGF1RTyrosine-protein kinase receptor. (1368 aa)
SHISA6LOW QUALITY PROTEIN: protein shisa-6 homolog. (554 aa)
LOC111187417Tyrosine-protein kinase. (612 aa)
IL18R1Interleukin-18 receptor 1 isoform X1. (539 aa)
IL6STInterleukin-6 receptor subunit beta. (918 aa)
CHRNA2Neuronal acetylcholine receptor subunit alpha-2 isoform X1. (589 aa)
SHISA8Uncharacterized protein. (399 aa)
LOC111186752T-cell receptor-associated transmembrane adapter 1. (185 aa)
CHRNA4Neuronal acetylcholine receptor subunit alpha-4 isoform X1. (826 aa)
ITGAEIntegrin alpha-E; Belongs to the integrin alpha chain family. (1173 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (616 aa)
DLG4Disks large homolog 4 isoform X1; Belongs to the MAGUK family. (752 aa)
RAMP3Receptor activity-modifying protein 3. (151 aa)
CSF2RBCytokine receptor common subunit beta. (902 aa)
CD6T-cell differentiation antigen CD6 isoform X1. (675 aa)
TSPAN32Tetraspanin-32 isoform X1; Belongs to the tetraspanin (TM4SF) family. (571 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (375 aa)
VWC2Brorin. (319 aa)
ITGB4Integrin beta. (1826 aa)
ITGALIntegrin alpha-L; Belongs to the integrin alpha chain family. (1166 aa)
GRIA1Glutamate receptor 1 isoform X1. (906 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (767 aa)
CACNG5Voltage-dependent calcium channel gamma-5 subunit isoform X1. (275 aa)
GRIN2CGlutamate receptor ionotropic, NMDA 2C isoform X1. (1265 aa)
CSF2Granulocyte-macrophage colony-stimulating factor. (144 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
CD79BB-cell antigen receptor complex-associated protein beta chain isoform X1. (230 aa)
ITGAMIntegrin alpha-M; Belongs to the integrin alpha chain family. (872 aa)
SHISA7Protein shisa-7 isoform X1. (677 aa)
CPT1CCarnitine O-palmitoyltransferase 1, brain isoform isoform X1. (836 aa)
LOC111182106Integrin alpha-X-like isoform X1; Belongs to the integrin alpha chain family. (1210 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (789 aa)
OLFM3Noelin-3 isoform X1. (478 aa)
CACNG3Voltage-dependent calcium channel gamma-3 subunit isoform X1. (315 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa)
TFR2Transferrin receptor protein 2 isoform X1. (805 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (496 aa)
GRIA2Glutamate receptor 2 isoform X5. (940 aa)
LOC111179199Serotransferrin-like; Belongs to the transferrin family. (706 aa)
HFE2Hemojuvelin isoform X1. (427 aa)
CD79AB-cell antigen receptor complex-associated protein alpha chain. (223 aa)
CBFBCore-binding factor subunit beta isoform X1; Belongs to the membrane-bound acyltransferase family. (514 aa)
GRIN2DLOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2D. (1334 aa)
CHRNA3Neuronal acetylcholine receptor subunit alpha-3. (510 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
ITGA10Integrin alpha-10; Belongs to the integrin alpha chain family. (1167 aa)
GRIN1Glutamate receptor ionotropic, NMDA 1 isoform X1. (959 aa)
GRID2Glutamate receptor ionotropic, delta-2 isoform X1. (1007 aa)
EPS8Epidermal growth factor receptor kinase substrate 8. (818 aa)
ITGA8Integrin alpha-8 isoform X1; Belongs to the integrin alpha chain family. (1062 aa)
GRIN2BGlutamate receptor ionotropic, NMDA 2B. (1499 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (516 aa)
CHRNA7Neuronal acetylcholine receptor subunit alpha-7 isoform X2. (499 aa)
CHRNA5Neuronal acetylcholine receptor subunit alpha-5 isoform X1. (475 aa)
EMILIN1EMILIN-1. (1015 aa)
ITGA11Integrin alpha-11; Belongs to the integrin alpha chain family. (1188 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
CHRNB4Neuronal acetylcholine receptor subunit beta-4. (495 aa)
GRIK3Glutamate receptor ionotropic, kainate 3 isoform X1. (963 aa)
GNAT1Guanine nucleotide-binding protein G(T) subunit alpha-1. (350 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (572 aa)
ITGA6Integrin alpha-6 isoform X1; Belongs to the integrin alpha chain family. (1091 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (546 aa)
ITGA7Integrin alpha-7 isoform X1; Belongs to the integrin alpha chain family. (1141 aa)
ABHD6Monoacylglycerol lipase ABHD6. (337 aa)
AMHR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (597 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (808 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (819 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3. (1338 aa)
LOC111171171Integrin alpha-M-like. (296 aa)
CHRNA1Acetylcholine receptor subunit alpha isoform X1. (457 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
CHRNDAcetylcholine receptor subunit delta isoform X1. (517 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
TLR6Toll-like receptor 6; Belongs to the Toll-like receptor family. (797 aa)
GRIN3BGlutamate receptor ionotropic, NMDA 3B isoform X5; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1034 aa)
VWC2LVon Willebrand factor C domain-containing protein 2-like. (222 aa)
ITGAVIntegrin alpha-V isoform X2; Belongs to the integrin alpha chain family. (1048 aa)
ITGA4Integrin alpha-4 isoform X1; Belongs to the integrin alpha chain family. (1033 aa)
CHRNA9Neuronal acetylcholine receptor subunit alpha-9. (480 aa)
LOC111171159LOW QUALITY PROTEIN: acetylcholine receptor subunit beta-like; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (258 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (800 aa)
CALCRLCalcitonin gene-related peptide type 1 receptor; Belongs to the G-protein coupled receptor 2 family. (462 aa)
DLG3Disks large homolog 3 isoform X1; Belongs to the MAGUK family. (849 aa)
GP9Platelet glycoprotein IX. (177 aa)
SYKTyrosine-protein kinase. (626 aa)
ITGA2BIntegrin alpha-IIb; Belongs to the integrin alpha chain family. (1034 aa)
GPR156Probable G-protein coupled receptor 156. (815 aa)
CD40Tumor necrosis factor receptor superfamily member 5 isoform X1. (284 aa)
GRIA3Glutamate receptor 3 isoform X1. (888 aa)
PORCNProtein-serine O-palmitoleoyltransferase porcupine isoform X1; Belongs to the membrane-bound acyltransferase family. (461 aa)
CD247T-cell surface glycoprotein CD3 zeta chain isoform X1. (185 aa)
IL6RInterleukin-6 receptor subunit alpha isoform X1. (465 aa)
HTR3B5-hydroxytryptamine receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (448 aa)
HTRA2Serine protease HTRA2, mitochondrial. (458 aa)
HFEHereditary hemochromatosis protein isoform X1; Belongs to the MHC class I family. (356 aa)
CHRNB2Neuronal acetylcholine receptor subunit beta-2. (502 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1 isoform X1. (965 aa)
STXBP5Syntaxin-binding protein 5 isoform X5. (1181 aa)
GRIA4Glutamate receptor 4 isoform X1. (902 aa)
ITGA3Integrin alpha-3 isoform X1; Belongs to the integrin alpha chain family. (1068 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
GRIK4Glutamate receptor ionotropic, kainate 4 isoform X1. (957 aa)
INSRRTyrosine-protein kinase receptor. (1301 aa)
IL12RB1Interleukin-12 receptor subunit beta-1 isoform X1. (726 aa)
HTR3A5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (483 aa)
CD3ET-cell surface glycoprotein CD3 epsilon chain. (197 aa)
IL27RAInterleukin-27 receptor subunit alpha isoform X1. (656 aa)
CD3GT-cell surface glycoprotein CD3 gamma chain. (178 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
CD3DT-cell surface glycoprotein CD3 delta chain. (171 aa)
RAMP2Receptor activity-modifying protein 2. (177 aa)
GRM1Metabotropic glutamate receptor 1. (1195 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (553 aa)
RNF31E3 ubiquitin-protein ligase RNF31 isoform X1. (1094 aa)
INSRTyrosine-protein kinase receptor. (1392 aa)
ITGA9Integrin alpha-9; Belongs to the integrin alpha chain family. (1035 aa)
GRIK2Glutamate receptor ionotropic, kainate 2 isoform X2. (908 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A. (1464 aa)
SHISA9Protein shisa-9 isoform X1. (466 aa)
IFNLR1Interferon lambda receptor 1 isoform X1. (535 aa)
CNTFRCiliary neurotrophic factor receptor subunit alpha isoform X1. (374 aa)
GP1BBPlatelet glycoprotein Ib beta chain. (205 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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