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| | RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa) |
| | PRDM1 | PR domain zinc finger protein 1 isoform X1. (820 aa) |
| | XBP1 | LOW QUALITY PROTEIN: X-box-binding protein 1. (392 aa) |
| | C1QC | Complement C1q subcomponent subunit C. (245 aa) |
| | LOC111163731 | C-C motif chemokine. (93 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (215 aa) |
| | LIF | Leukemia inhibitory factor. (202 aa) |
| | CCL19 | C-C motif chemokine. (159 aa) |
| | PLA2G3 | Group 3 secretory phospholipase A2 isoform X1. (516 aa) |
| | TNFSF9 | Tumor necrosis factor ligand superfamily member 9; Belongs to the tumor necrosis factor family. (252 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) |
| | SHB | SH2 domain-containing adapter protein B. (507 aa) |
| | POU4F2 | POU domain protein. (407 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (180 aa) |
| | IL1RL2 | Interleukin-1 receptor-like 2 isoform X1. (570 aa) |
| | CTNNBIP1 | Beta-catenin-interacting protein 1. (81 aa) |
| | TESC | Calcineurin B homologous protein 3. (214 aa) |
| | FBXO7 | F-box only protein 7 isoform X1. (523 aa) |
| | FBXW7 | F-box/WD repeat-containing protein 7 isoform X1. (707 aa) |
| | TMEM131L | Transmembrane protein 131-like isoform X1. (1608 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] isoform X1. (687 aa) |
| | LOC111187428 | Interleukin-1. (118 aa) |
| | TOB2 | Protein Tob2. (343 aa) |
| | PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (629 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa) |
| | PIK3R6 | Phosphoinositide 3-kinase regulatory subunit 6 isoform X1. (881 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | IL7R | Interleukin-7 receptor subunit alpha isoform X1. (459 aa) |
| | ZC3H8 | Zinc finger CCCH domain-containing protein 8 isoform X1. (308 aa) |
| | EVI2B | Protein EVI2B. (451 aa) |
| | CEBPB | CCAAT/enhancer-binding protein. (345 aa) |
| | NF1 | Neurofibromin isoform X1. (2873 aa) |
| | LOC111187417 | Tyrosine-protein kinase. (612 aa) |
| | NFAM1 | NFAT activation molecule 1. (264 aa) |
| | ZBTB46 | Zinc finger and BTB domain-containing protein 46. (590 aa) |
| | NFKBIZ | NF-kappa-B inhibitor zeta. (726 aa) |
| | SOX13 | Transcription factor SOX-13. (644 aa) |
| | FOXN1 | Forkhead box protein N1. (645 aa) |
| | GLI3 | Transcriptional activator GLI3 isoform X1. (1587 aa) |
| | SH3RF1 | E3 ubiquitin-protein ligase SH3RF1 isoform X1. (872 aa) |
| | SOX12 | Transcription factor SOX. (312 aa) |
| | AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1087 aa) |
| | ADA | Adenosine deaminase isoform X1. (416 aa) |
| | BAD | Bcl2-associated agonist of cell death. (168 aa) |
| | GPR137 | Integral membrane protein GPR137 isoform X1. (395 aa) |
| | ZMIZ1 | Zinc finger MIZ domain-containing protein 1 isoform X1. (1071 aa) |
| | VSIR | V-type immunoglobulin domain-containing suppressor of T-cell activation. (311 aa) |
| | MAFB | Transcription factor MafB. (323 aa) |
| | NDFIP1 | NEDD4 family-interacting protein 1. (221 aa) |
| | SART1 | U4/U6.U5 tri-snRNP-associated protein 1. (803 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa) |
| | FAM213A | Redox-regulatory protein FAM213A isoform X3. (289 aa) |
| | AMBRA1 | Activating molecule in BECN1-regulated autophagy protein 1 isoform X1. (1295 aa) |
| | IL27 | Interleukin-27 subunit alpha. (237 aa) |
| | CD74 | HLA class II histocompatibility antigen gamma chain isoform X1. (278 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa) |
| | FBN1 | Fibrillin-1 isoform X1. (2871 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (670 aa) |
| | TMEM176B | Transmembrane protein 176B. (265 aa) |
| | TMEM176A | Transmembrane protein 176A. (221 aa) |
| | PPARGC1B | Peroxisome proliferator-activated receptor gamma coactivator 1-beta isoform X1. (1173 aa) |
| | HOXA7 | Homeobox protein Hox-A7. (233 aa) |
| | CLPTM1 | Cleft lip and palate transmembrane protein 1. (660 aa) |
| | FOXJ1 | Forkhead box protein J1. (422 aa) |
| | RASGRP1 | RAS guanyl-releasing protein 1 isoform X1. (870 aa) |
| | KLF10 | Krueppel-like factor 10 isoform X2. (494 aa) |
| | SMAD7 | Mothers against decapentaplegic homolog. (426 aa) |
| | IRF1 | Interferon regulatory factor. (322 aa) |
| | CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (554 aa) |
| | NOTCH2 | Neurogenic locus notch homolog protein 2 isoform X1. (2471 aa) |
| | PIAS3 | E3 SUMO-protein ligase PIAS3 isoform X1. (628 aa) |
| | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 isoform X1. (687 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa) |
| | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X1. (850 aa) |
| | CD83 | CD83 antigen isoform X1. (195 aa) |
| | CD101 | Immunoglobulin superfamily member 2 isoform X1. (1018 aa) |
| | NEDD9 | Enhancer of filamentation 1 isoform X1. (829 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (521 aa) |
| | IL4I1 | L-amino-acid oxidase isoform X1. (653 aa) |
| | TMEM64 | Transmembrane protein 64. (382 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa) |
| | CDK6 | Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily. (326 aa) |
| | TREM2 | Triggering receptor expressed on myeloid cells 2. (294 aa) |
| | ZEB1 | Zinc finger E-box-binding homeobox 1 isoform X2. (1110 aa) |
| | AXL | LOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO. (887 aa) |
| | GATA3 | Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa) |
| | IL34 | Interleukin-34. (235 aa) |
| | FANCA | Fanconi anemia group A protein isoform X1. (1522 aa) |
| | DCSTAMP | LOW QUALITY PROTEIN: dendritic cell-specific transmembrane protein. (510 aa) |
| | DUSP10 | Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa) |
| | RC3H2 | Roquin-2. (1189 aa) |
| | ABL1 | Tyrosine-protein kinase. (1148 aa) |
| | LOC111176900 | GTPase IMAP family member 5-like isoform X1. (332 aa) |
| | ZFPM1 | Zinc finger protein ZFPM1 isoform X1. (1069 aa) |
| | LAG3 | Lymphocyte activation gene 3 protein. (493 aa) |
| | LOC111178668 | HLA class II histocompatibility antigen, DO alpha chain-like; Belongs to the MHC class II family. (250 aa) |
| | BRAF | Serine/threonine-protein kinase B-raf isoform X1. (762 aa) |
| | HLX | H2.0-like homeobox protein. (488 aa) |
| | IL17A | interleukin-17A. (155 aa) |
| | CUL4A | cullin-4A; Belongs to the cullin family. (761 aa) |
| | GAS6 | Growth arrest-specific protein 6. (671 aa) |
| | LOC111174846 | Transmembrane protein 178A-like isoform X1. (177 aa) |
| | ZFP36L2 | mRNA decay activator protein ZFP36L2. (493 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) |
| | ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (941 aa) |
| | TAL1 | T-cell acute lymphocytic leukemia protein 1 isoform X1. (328 aa) |
| | SLC46A2 | Thymic stromal cotransporter homolog. (475 aa) |
| | POU4F1 | POU domain protein. (422 aa) |
| | NRARP | Notch-regulated ankyrin repeat-containing protein. (114 aa) |
| | PCID2 | PCI domain-containing protein 2 isoform X2. (399 aa) |
| | CD27 | CD27 antigen isoform X1. (251 aa) |
| | FOXP1 | Forkhead box protein P1 isoform X1. (673 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (461 aa) |
| | FSHR | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) |
| | LOC111175407 | Amine oxidase. (524 aa) |
| | LTF | Lactotransferrin; Belongs to the transferrin family. (710 aa) |
| | RHOA | Transforming protein RhoA. (193 aa) |
| | GPR68 | Ovarian cancer G-protein coupled receptor 1; Belongs to the G-protein coupled receptor 1 family. (371 aa) |
| | ZFP36L1 | mRNA decay activator protein ZFP36L1. (338 aa) |
| | ZC3H12A | Endoribonuclease ZC3H12A. (583 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | RNF41 | E3 ubiquitin-protein ligase NRDP1 isoform X1. (317 aa) |
| | TNFSF11 | Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa) |
| | TCTA | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. (106 aa) |
| | TLR9 | LOW QUALITY PROTEIN: toll-like receptor 9. (1323 aa) |
| | SOS1 | Son of sevenless homolog 1 isoform X1. (1333 aa) |
| | LOC111174848 | Uncharacterized protein LOC111174848 isoform X1. (334 aa) |
| | SOCS5 | Suppressor of cytokine signaling 5. (536 aa) |
| | ADAM8 | Disintegrin and metalloproteinase domain-containing protein 8 isoform X1. (838 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | MITF | Microphthalmia-associated transcription factor isoform X1. (526 aa) |
| | NCKAP1L | Nck-associated protein 1-like isoform X1. (1156 aa) |
| | SLC9B2 | Sodium/hydrogen exchanger 9B2 isoform X1. (536 aa) |
| | SOS2 | Son of sevenless homolog 2 isoform X1. (1332 aa) |
| | ZBTB1 | Zinc finger and BTB domain-containing protein 1. (713 aa) |
| | INPP5D | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1150 aa) |
| | SFRP1 | Secreted frizzled-related protein 1. (308 aa) |
| | CREB1 | Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa) |
| | CTLA4 | Cytotoxic T-lymphocyte protein 4 isoform X1. (223 aa) |
| | RHOH | Rho-related GTP-binding protein RhoH. (191 aa) |
| | PPP2R3C | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1. (453 aa) |
| | BMP4 | Bone morphogenetic protein 4 isoform X2. (408 aa) |
| | OCSTAMP | LOW QUALITY PROTEIN: osteoclast stimulatory transmembrane protein. (566 aa) |
| | FANCD2 | Fanconi anemia group D2 protein isoform X1. (1458 aa) |
| | BCL6 | B-cell lymphoma 6 protein. (706 aa) |
| | IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa) |
| | TNFAIP6 | Tumor necrosis factor-inducible gene 6 protein isoform X1. (284 aa) |
| | PRELID1 | PRELI domain-containing protein 1, mitochondrial. (219 aa) |
| | CD28 | T-cell-specific surface glycoprotein CD28. (265 aa) |
| | CASP8 | Caspase-8; Belongs to the peptidase C14A family. (486 aa) |
| | RC3H1 | Roquin-1 isoform X1. (1135 aa) |
| | GPR55 | G-protein coupled receptor 55 isoform X1; Belongs to the G-protein coupled receptor 1 family. (407 aa) |
| | CASP10 | Caspase-10; Belongs to the peptidase C14A family. (518 aa) |
| | LEF1 | Lymphoid enhancer-binding factor 1 isoform X1. (414 aa) |
| | TFE3 | Transcription factor E3 isoform X1. (575 aa) |
| | FSTL3 | Follistatin-related protein 3. (262 aa) |
| | AGER | Advanced glycosylation end product-specific receptor isoform X1. (631 aa) |
| | CARD11 | Caspase recruitment domain-containing protein 11 isoform X1. (1154 aa) |
| | LOC111169054 | NF-kappa-B-activating protein. (417 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa) |
| | IL2RG | Cytokine receptor common subunit gamma isoform X1. (381 aa) |
| | DROSHA | Ribonuclease 3 isoform X1. (1414 aa) |
| | SYK | Tyrosine-protein kinase. (626 aa) |
| | FES | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa) |
| | HCLS1 | Hematopoietic lineage cell-specific protein. (481 aa) |
| | FOXP3 | Forkhead box protein P3. (431 aa) |
| | SLAMF8 | SLAM family member 8 isoform X1. (318 aa) |
| | LOXL3 | Lysyl oxidase homolog 3 isoform X1. (772 aa) |
| | CTNNB1 | Catenin beta-1. (781 aa) |
| | PGLYRP2 | N-acetylmuramoyl-L-alanine amidase isoform X1. (581 aa) |
| | EGR3 | Early growth response protein 3 isoform X1. (387 aa) |
| | ZBTB7B | Zinc finger and BTB domain-containing protein 7B. (541 aa) |
| | PTPRC | Receptor-type tyrosine-protein phosphatase C isoform X1. (1258 aa) |
| | ZBTB16 | Zinc finger and BTB domain-containing protein 16. (673 aa) |
| | SASH3 | SAM and SH3 domain-containing protein 3. (380 aa) |
| | LOC111167902 | Cytochrome P450 26B1 isoform X1; Belongs to the cytochrome P450 family. (512 aa) |
| | CRTAM | Cytotoxic and regulatory T-cell molecule isoform X1. (391 aa) |
| | RASSF2 | Ras association domain-containing protein 2 isoform X1. (420 aa) |
| | HAX1 | HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (276 aa) |
| | UBASH3B | Ubiquitin-associated and SH3 domain-containing protein B isoform X1. (649 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1255 aa) |
| | KAT2A | Histone acetyltransferase KAT2A isoform X1. (878 aa) |
| | TNFRSF11B | Tumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. (401 aa) |
| | FBXW9 | F-box/WD repeat-containing protein 9 isoform X1. (461 aa) |
| | LOC111167004 | LOW QUALITY PROTEIN: peptidoglycan recognition protein 3-like. (277 aa) |
| | LYN | Tyrosine-protein kinase. (518 aa) |
| | IL7 | Interleukin-7 isoform X1. (226 aa) |
| | APCS | LOW QUALITY PROTEIN: serum amyloid P-component. (139 aa) |
| | LOC111166997 | Fc receptor-like protein 3 isoform X2. (726 aa) |
| | LOC111166483 | Signal transducer and activator of transcription. (787 aa) |
| | STAT5A | Signal transducer and activator of transcription. (818 aa) |
| | MMP14 | Matrix metalloproteinase-14. (582 aa) |
| | TBX21 | T-box transcription factor TBX21. (535 aa) |
| | RARA | Retinoic acid receptor alpha isoform X5. (584 aa) |
| | LOC111166170 | C-type lectin domain family 4 member G-like isoform X1. (313 aa) |
| | IKZF3 | Zinc finger protein Aiolos isoform X1. (509 aa) |
| | MYB | Transcriptional activator Myb isoform X3. (761 aa) |
| | VNN1 | Pantetheinase. (514 aa) |
| | LRRC17 | Leucine-rich repeat-containing protein 17 isoform X1. (440 aa) |
| | TOX | Thymocyte selection-associated high mobility group box protein TOX isoform X1. (517 aa) |
| | TRIB1 | Tribbles homolog 1. (372 aa) |
| | ZNF683 | LOW QUALITY PROTEIN: tissue-resident T-cell transcription regulator protein ZNF683. (505 aa) |
| | GPR137B | Integral membrane protein GPR137B. (385 aa) |
| | FGL2 | Fibroleukin. (440 aa) |
| | HSF1 | Heat shock factor protein 1 isoform X1. (564 aa) |
| | FOXO3 | Forkhead box protein O3. (672 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type 2 isoform X3. (474 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
