70 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RC3H2	Roquin-2. (1189 aa)
	ZFPM1	Zinc finger protein ZFPM1 isoform X1. (1069 aa)
	LAG3	Lymphocyte activation gene 3 protein. (493 aa)
	HLX	H2.0-like homeobox protein. (488 aa)
	CUL4A	cullin-4A; Belongs to the cullin family. (761 aa)
	LOC111174846	Transmembrane protein 178A-like isoform X1. (177 aa)
	NRARP	Notch-regulated ankyrin repeat-containing protein. (114 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (461 aa)
	LTF	Lactotransferrin; Belongs to the transferrin family. (710 aa)
	GPR68	Ovarian cancer G-protein coupled receptor 1; Belongs to the G-protein coupled receptor 1 family. (371 aa)
	ZC3H12A	Endoribonuclease ZC3H12A. (583 aa)
	TCTA	T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. (106 aa)
	LOC111174848	Uncharacterized protein LOC111174848 isoform X1. (334 aa)
	SOCS5	Suppressor of cytokine signaling 5. (536 aa)
	ANXA1	Annexin. (346 aa)
	INPP5D	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1150 aa)
	SFRP1	Secreted frizzled-related protein 1. (308 aa)
	CTLA4	Cytotoxic T-lymphocyte protein 4 isoform X1. (223 aa)
	BMP4	Bone morphogenetic protein 4 isoform X2. (408 aa)
	BCL6	B-cell lymphoma 6 protein. (706 aa)
	IHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
	TNFAIP6	Tumor necrosis factor-inducible gene 6 protein isoform X1. (284 aa)
	RC3H1	Roquin-1 isoform X1. (1135 aa)
	GPR55	G-protein coupled receptor 55 isoform X1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
	FSTL3	Follistatin-related protein 3. (262 aa)
	FOXP3	Forkhead box protein P3. (431 aa)
	LOXL3	Lysyl oxidase homolog 3 isoform X1. (772 aa)
	CTNNB1	Catenin beta-1. (781 aa)
	PGLYRP2	N-acetylmuramoyl-L-alanine amidase isoform X1. (581 aa)
	ZBTB7B	Zinc finger and BTB domain-containing protein 7B. (541 aa)
	UBASH3B	Ubiquitin-associated and SH3 domain-containing protein B isoform X1. (649 aa)
	ERBB2	Receptor protein-tyrosine kinase. (1255 aa)
	TNFRSF11B	Tumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. (401 aa)
	FBXW9	F-box/WD repeat-containing protein 9 isoform X1. (461 aa)
	LOC111167004	LOW QUALITY PROTEIN: peptidoglycan recognition protein 3-like. (277 aa)
	LYN	Tyrosine-protein kinase. (518 aa)
	APCS	LOW QUALITY PROTEIN: serum amyloid P-component. (139 aa)
	TBX21	T-box transcription factor TBX21. (535 aa)
	RARA	Retinoic acid receptor alpha isoform X5. (584 aa)
	LOC111166170	C-type lectin domain family 4 member G-like isoform X1. (313 aa)
	LRRC17	Leucine-rich repeat-containing protein 17 isoform X1. (440 aa)
	TRIB1	Tribbles homolog 1. (372 aa)
	GPR137B	Integral membrane protein GPR137B. (385 aa)
	FGL2	Fibroleukin. (440 aa)
	PTPN2	Tyrosine-protein phosphatase non-receptor type 2 isoform X3. (474 aa)
	MYC	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
	C1QC	Complement C1q subcomponent subunit C. (245 aa)
	LOC111163731	C-C motif chemokine. (93 aa)
	SOCS1	Suppressor of cytokine signaling 1. (215 aa)
	FBXO7	F-box only protein 7 isoform X1. (523 aa)
	FBXW7	F-box/WD repeat-containing protein 7 isoform X1. (707 aa)
	TMEM131L	Transmembrane protein 131-like isoform X1. (1608 aa)
	TOB2	Protein Tob2. (343 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	ZC3H8	Zinc finger CCCH domain-containing protein 8 isoform X1. (308 aa)
	NF1	Neurofibromin isoform X1. (2873 aa)
	ZBTB46	Zinc finger and BTB domain-containing protein 46. (590 aa)
	GLI3	Transcriptional activator GLI3 isoform X1. (1587 aa)
	GPR137	Integral membrane protein GPR137 isoform X1. (395 aa)
	MAFB	Transcription factor MafB. (323 aa)
	CD74	HLA class II histocompatibility antigen gamma chain isoform X1. (278 aa)
	FBN1	Fibrillin-1 isoform X1. (2871 aa)
	TMEM176B	Transmembrane protein 176B. (265 aa)
	TMEM176A	Transmembrane protein 176A. (221 aa)
	HOXA7	Homeobox protein Hox-A7. (233 aa)
	FOXJ1	Forkhead box protein J1. (422 aa)
	SMAD7	Mothers against decapentaplegic homolog. (426 aa)
	IRF1	Interferon regulatory factor. (322 aa)
	PIAS3	E3 SUMO-protein ligase PIAS3 isoform X1. (628 aa)
	CDK6	Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily. (326 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APCS	C1QC	A0A2Y9LZA8	A0A2Y9LFX6	LOW QUALITY PROTEIN: serum amyloid P-component.	Complement C1q subcomponent subunit C.	0.413
BCL6	CTLA4	A0A2Y9MT32	A0A2Y9MVX1	B-cell lymphoma 6 protein.	Cytotoxic T-lymphocyte protein 4 isoform X1.	0.645
BCL6	FOXP3	A0A2Y9MT32	A0A2Y9MEL9	B-cell lymphoma 6 protein.	Forkhead box protein P3.	0.778
BCL6	MYC	A0A2Y9MT32	A0A2Y9LJB2	B-cell lymphoma 6 protein.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.413
BCL6	TBX21	A0A2Y9MT32	A0A2Y9LVI8	B-cell lymphoma 6 protein.	T-box transcription factor TBX21.	0.612
BMP4	CTNNB1	A0A2Y9MV04	A0A2Y9MAY9	Bone morphogenetic protein 4 isoform X2.	Catenin beta-1.	0.619
BMP4	IHH	A0A2Y9MV04	A0A2Y9MSV0	Bone morphogenetic protein 4 isoform X2.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.638
BMP4	SHH	A0A2Y9MV04	A0A2Y9NDZ2	Bone morphogenetic protein 4 isoform X2.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.683
BMP4	SMAD7	A0A2Y9MV04	A0A2Y9PCL8	Bone morphogenetic protein 4 isoform X2.	Mothers against decapentaplegic homolog.	0.700
C1QC	APCS	A0A2Y9LFX6	A0A2Y9LZA8	Complement C1q subcomponent subunit C.	LOW QUALITY PROTEIN: serum amyloid P-component.	0.413
CDK6	CTNNB1	A0A2Y9P3B0	A0A2Y9MAY9	Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily.	Catenin beta-1.	0.542
CDK6	FBXO7	A0A2Y9P3B0	A0A2Y9QDP1	Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily.	F-box only protein 7 isoform X1.	0.629
CDK6	IRF1	A0A2Y9P3B0	A0A2Y9PC38	Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily.	Interferon regulatory factor.	0.474
CDK6	MYC	A0A2Y9P3B0	A0A2Y9LJB2	Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.418
CTLA4	BCL6	A0A2Y9MVX1	A0A2Y9MT32	Cytotoxic T-lymphocyte protein 4 isoform X1.	B-cell lymphoma 6 protein.	0.645
CTLA4	FGL2	A0A2Y9MVX1	A0A2Y9LN56	Cytotoxic T-lymphocyte protein 4 isoform X1.	Fibroleukin.	0.606
CTLA4	FOXP3	A0A2Y9MVX1	A0A2Y9MEL9	Cytotoxic T-lymphocyte protein 4 isoform X1.	Forkhead box protein P3.	0.760
CTLA4	LAG3	A0A2Y9MVX1	A0A2Y9NUG5	Cytotoxic T-lymphocyte protein 4 isoform X1.	Lymphocyte activation gene 3 protein.	0.800
CTLA4	LYN	A0A2Y9MVX1	A0A2Y9LZZ2	Cytotoxic T-lymphocyte protein 4 isoform X1.	Tyrosine-protein kinase.	0.476
CTLA4	PIK3R1	A0A2Y9MVX1	A0A2Y9Q8T5	Cytotoxic T-lymphocyte protein 4 isoform X1.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.555