STRINGSTRING
FIS1 FIS1 AKT2 AKT2 BBC3 BBC3 CD81 CD81 DPP10 DPP10 STX3 STX3 CLN3 CLN3 LGALS3 LGALS3 R3HDM1 R3HDM1 R3HDM2 R3HDM2 PRKCI PRKCI ACSL3 ACSL3 STAC3 STAC3 MFF MFF ARF6 ARF6 AKAP5 AKAP5 TNFAIP6 TNFAIP6 VIL1 VIL1 DLG1 DLG1 CIB1 CIB1 LOC111170545 LOC111170545 HRAS HRAS AGPAT4 AGPAT4 GPER1 GPER1 LOC111167795 LOC111167795 WNK3 WNK3 WNT3A WNT3A MIEF2 MIEF2 SQSTM1 SQSTM1 ATP2C1 ATP2C1 ITGA3 ITGA3 ERBB2 ERBB2 EZR EZR STAC2 STAC2 RACK1 RACK1 ANXA13 ANXA13 CEMIP CEMIP LOC111165935 LOC111165935 FYN FYN MESD MESD STAC STAC ITGB1BP1 ITGB1BP1 TNF TNF LOC111187154 LOC111187154 RER1 RER1 SPTBN1 SPTBN1 ARHGEF16 ARHGEF16 EPHA2 EPHA2 PIK3R1 PIK3R1 RANGRF RANGRF MYO1C MYO1C KCNB1 KCNB1 PDPK1 PDPK1 MIEF1 MIEF1 CDK5R1 CDK5R1 EGFR EGFR RAMP3 RAMP3 ZDHHC5 ZDHHC5 LRP4 LRP4 DLG2 DLG2 ATP2B4 ATP2B4 AKT1 AKT1 TCAF1 TCAF1 KIF5B KIF5B LOC111177285 LOC111177285 EPHA3 EPHA3 EFCAB7 EFCAB7 SLC51B SLC51B CDK5 CDK5 C2CD5 C2CD5 PTPN9 PTPN9 PLS1 PLS1 PDZK1 PDZK1 ITGB1 ITGB1 CNST CNST TREM2 TREM2 TGFB1 TGFB1 AGR2 AGR2 PDCD5 PDCD5 LOC111181166 LOC111181166 CNPY4 CNPY4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
BBC3Bcl-2-binding component 3. (193 aa)
CD81Tetraspanin. (236 aa)
DPP10Inactive dipeptidyl peptidase 10 isoform X1; Belongs to the peptidase S9B family. (840 aa)
STX3Syntaxin-3 isoform X1; Belongs to the syntaxin family. (289 aa)
CLN3Battenin. (436 aa)
LGALS3Galectin. (256 aa)
R3HDM1R3H domain-containing protein 1 isoform X1. (1129 aa)
R3HDM2R3H domain-containing protein 2 isoform X1. (1048 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (707 aa)
ACSL3long-chain-fatty-acid--CoA ligase 3. (720 aa)
STAC3SH3 and cysteine-rich domain-containing protein 3 isoform X1. (360 aa)
MFFMitochondrial fission factor isoform X1. (353 aa)
ARF6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
AKAP5A-kinase anchor protein 5. (428 aa)
TNFAIP6Tumor necrosis factor-inducible gene 6 protein isoform X1. (284 aa)
VIL1Villin-1 isoform X1. (827 aa)
DLG1Disks large homolog 1 isoform X1; Belongs to the MAGUK family. (927 aa)
CIB1Calcium and integrin-binding protein 1. (191 aa)
LOC111170545Rho-related GTP-binding protein RhoG. (191 aa)
HRASGTPase HRas isoform X1. (189 aa)
AGPAT41-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X1. (835 aa)
GPER1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
LOC111167795Rho-related GTP-binding protein RhoG-like isoform X1. (230 aa)
WNK3Serine/threonine-protein kinase WNK3 isoform X1. (1780 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
MIEF2Mitochondrial dynamics protein MID49 isoform X1. (460 aa)
SQSTM1Sequestosome-1. (440 aa)
ATP2C1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1027 aa)
ITGA3Integrin alpha-3 isoform X1; Belongs to the integrin alpha chain family. (1068 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
EZREzrin. (586 aa)
STAC2SH3 and cysteine-rich domain-containing protein 2 isoform X1. (409 aa)
RACK1Receptor of activated protein C kinase 1. (317 aa)
ANXA13Annexin. (327 aa)
CEMIPCell migration-inducing and hyaluronan-binding protein. (1431 aa)
LOC111165935Ras-like protein isoform X1. (285 aa)
FYNTyrosine-protein kinase. (537 aa)
MESDLDLR chaperone MESD. (232 aa)
STACSH3 and cysteine-rich domain-containing protein isoform X1. (402 aa)
ITGB1BP1Integrin beta-1-binding protein 1 isoform X1. (206 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
LOC111187154Ephrin type-A receptor 2-like. (171 aa)
RER1Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment. (196 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2363 aa)
ARHGEF16Rho guanine nucleotide exchange factor 16 isoform X1. (708 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
RANGRFRan guanine nucleotide release factor isoform X1. (186 aa)
MYO1CUnconventional myosin-Ic isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1063 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
MIEF1Mitochondrial dynamics protein MID51. (463 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
RAMP3Receptor activity-modifying protein 3. (151 aa)
ZDHHC5Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (715 aa)
LRP4Low-density lipoprotein receptor-related protein 4. (1905 aa)
DLG2Disks large homolog 2 isoform X1. (994 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
TCAF1TRPM8 channel-associated factor 1 isoform X1. (1016 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (964 aa)
LOC111177285TRPM8 channel-associated factor 2-like. (919 aa)
EPHA3Ephrin type-A receptor 3. (984 aa)
EFCAB7EF-hand calcium-binding domain-containing protein 7 isoform X1. (656 aa)
SLC51BLOW QUALITY PROTEIN: organic solute transporter subunit beta. (130 aa)
CDK5Cyclin-dependent-like kinase 5; Belongs to the protein kinase superfamily. (292 aa)
C2CD5C2 domain-containing protein 5 isoform X1. (1051 aa)
PTPN9Tyrosine-protein phosphatase non-receptor type 9. (593 aa)
PLS1Plastin-1 isoform X1. (630 aa)
PDZK1Na(+)/H(+) exchange regulatory cofactor NHE-RF3 isoform X1. (518 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
CNSTConsortin isoform X1. (722 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (294 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
AGR2Anterior gradient protein 2 homolog. (175 aa)
PDCD5Programmed cell death protein 5. (125 aa)
LOC111181166CAP-Gly domain-containing linker protein 3. (547 aa)
CNPY4Protein canopy homolog 4 isoform X1. (230 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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