STRINGSTRING
CRKL CRKL PTPN11 PTPN11 PTPN1 PTPN1 CASS4 CASS4 NCK2 NCK2 GDNF GDNF ARHGEF16 ARHGEF16 PIK3R1 PIK3R1 PITPNM2 PITPNM2 SH2B3 SH2B3 GAB2 GAB2 LOC111186752 LOC111186752 CBLB CBLB LRP4 LRP4 PITPNM3 PITPNM3 CRK CRK NOX4 NOX4 PITPNM1 PITPNM1 LOC111183874 LOC111183874 PTPN14 PTPN14 ANGPT4 ANGPT4 PLCG1 PLCG1 SH2B2 SH2B2 SHC4 SHC4 GRB2 GRB2 SH2B1 SH2B1 FIZ1 FIZ1 CEACAM20 CEACAM20 NEDD9 NEDD9 TRADD TRADD GP6 GP6 LOC111180818 LOC111180818 CADM4 CADM4 ANGPT1 ANGPT1 FRS3 FRS3 TREM2 TREM2 CDH5 CDH5 FLT3LG FLT3LG BANK1 BANK1 GFRAL GFRAL PLCG2 PLCG2 DOCK4 DOCK4 NCK1 NCK1 GAS6 GAS6 TJP2 TJP2 HYAL2 HYAL2 ANGPT2 ANGPT2 KHDRBS1 KHDRBS1 RNF41 RNF41 BLNK BLNK SOCS5 SOCS5 EPHA4 EPHA4 MST1 MST1 FNTA FNTA DAZAP2 DAZAP2 FRS2 FRS2 GRB14 GRB14 SHC2 SHC2 ELMO2 ELMO2 BMPR2 BMPR2 ALKAL2 ALKAL2 CD247 CD247 PRR7 PRR7 PHYHIP PHYHIP ZPR1 ZPR1 LOC111169218 LOC111169218 DOK2 DOK2 NRTN NRTN PSPN PSPN SHC3 SHC3 ALKAL1 ALKAL1 PHYHIPL PHYHIPL TOB1 TOB1 CBL CBL MYOC MYOC SHC1 SHC1 LOC111166997 LOC111166997 RACK1 RACK1 PIK3R2 PIK3R2 PCNA PCNA DSCAM DSCAM CPNE3 CPNE3 PTPN2 PTPN2 MAP3K7 MAP3K7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CRKLCrk-like protein. (303 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (451 aa)
CASS4Cas scaffolding protein family member 4 isoform X1. (821 aa)
NCK2Cytoplasmic protein. (376 aa)
GDNFGlial cell line-derived neurotrophic factor. (185 aa)
ARHGEF16Rho guanine nucleotide exchange factor 16 isoform X1. (708 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
PITPNM2Membrane-associated phosphatidylinositol transfer protein 2. (1273 aa)
SH2B3SH2B adapter protein 3 isoform X1. (618 aa)
GAB2GRB2-associated-binding protein 2 isoform X1. (678 aa)
LOC111186752T-cell receptor-associated transmembrane adapter 1. (185 aa)
CBLBE3 ubiquitin-protein ligase CBL-B. (983 aa)
LRP4Low-density lipoprotein receptor-related protein 4. (1905 aa)
PITPNM3Membrane-associated phosphatidylinositol transfer protein 3 isoform X1. (1178 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
NOX4NADPH oxidase 4. (530 aa)
PITPNM1Membrane-associated phosphatidylinositol transfer protein 1. (1244 aa)
LOC111183874Protein Tob1-like. (205 aa)
PTPN14Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1187 aa)
ANGPT4Angiopoietin-4. (498 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
SH2B2SH2B adapter protein 2 isoform X1. (703 aa)
SHC4SHC-transforming protein 4. (630 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
SH2B1SH2B adapter protein 1 isoform X1. (795 aa)
FIZ1Flt3-interacting zinc finger protein 1 isoform X1. (631 aa)
CEACAM20LOW QUALITY PROTEIN: carcinoembryonic antigen-related cell adhesion molecule 20. (489 aa)
NEDD9Enhancer of filamentation 1 isoform X1. (829 aa)
TRADDTumor necrosis factor receptor type 1-associated DEATH domain protein. (315 aa)
GP6Platelet glycoprotein VI isoform X1. (464 aa)
LOC111180818Carcinoembryonic antigen-related cell adhesion molecule 1-like isoform X1. (278 aa)
CADM4Cell adhesion molecule 4. (388 aa)
ANGPT1Angiopoietin-1 isoform X1. (498 aa)
FRS3Fibroblast growth factor receptor substrate 3. (495 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (294 aa)
CDH5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (782 aa)
FLT3LGFms-related tyrosine kinase 3 ligand isoform X1. (328 aa)
BANK1B-cell scaffold protein with ankyrin repeats isoform X1. (785 aa)
GFRALLOW QUALITY PROTEIN: GDNF family receptor alpha-like. (397 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
DOCK4Dedicator of cytokinesis protein 4 isoform X1; Belongs to the DOCK family. (1971 aa)
NCK1Cytoplasmic protein. (377 aa)
GAS6Growth arrest-specific protein 6. (671 aa)
TJP2Tight junction protein ZO-2 isoform X2; Belongs to the MAGUK family. (1187 aa)
HYAL2Hyaluronidase. (476 aa)
ANGPT2Angiopoietin-2 isoform X1. (496 aa)
KHDRBS1KH domain-containing, RNA-binding, signal transduction-associated protein 1. (443 aa)
RNF41E3 ubiquitin-protein ligase NRDP1 isoform X1. (317 aa)
BLNKB-cell linker protein isoform X1. (528 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
EPHA4Ephrin type-A receptor 4 isoform X1. (986 aa)
MST1Hepatocyte growth factor-like protein isoform X1; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa)
FNTAProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha isoform X1. (371 aa)
DAZAP2DAZ-associated protein 2 isoform X2. (207 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
GRB14Growth factor receptor-bound protein 14 isoform X1. (540 aa)
SHC2SHC-transforming protein 2 isoform X1. (588 aa)
ELMO2Engulfment and cell motility protein 2 isoform X1. (720 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
ALKAL2ALK and LTK ligand 2 isoform X1. (152 aa)
CD247T-cell surface glycoprotein CD3 zeta chain isoform X1. (185 aa)
PRR7Proline-rich protein 7. (269 aa)
PHYHIPphytanoyl-CoA hydroxylase-interacting protein. (330 aa)
ZPR1Zinc finger protein ZPR1. (459 aa)
LOC111169218Tripartite motif-containing protein 6-like. (487 aa)
DOK2Docking protein 2. (411 aa)
NRTNNeurturin. (197 aa)
PSPNPersephin. (153 aa)
SHC3SHC-transforming protein 3. (588 aa)
ALKAL1ALK and LTK ligand 1. (121 aa)
PHYHIPLphytanoyl-CoA hydroxylase-interacting protein-like isoform X1. (376 aa)
TOB1Protein Tob1. (344 aa)
CBLE3 ubiquitin-protein ligase CBL isoform X1. (910 aa)
MYOCMyocilin. (476 aa)
SHC1SHC-transforming protein 1 isoform X1. (609 aa)
LOC111166997Fc receptor-like protein 3 isoform X2. (726 aa)
RACK1Receptor of activated protein C kinase 1. (317 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
DSCAMDown syndrome cell adhesion molecule isoform X2. (1577 aa)
CPNE3Copine-3. (533 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type 2 isoform X3. (474 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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