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ADAM8 ADAM8 ARG2 ARG2 ANXA1 ANXA1 HIF1A HIF1A BMP4 BMP4 LOC111169978 LOC111169978 PDCD1 PDCD1 PRELID1 PRELID1 CXCL12 CXCL12 PRKCQ PRKCQ PIK3CB PIK3CB PRKD2 PRKD2 AXL AXL BCL10 BCL10 FCAR FCAR BCL3 BCL3 RAPGEF2 RAPGEF2 NOC2L NOC2L GPAM GPAM HCLS1 HCLS1 EFNA1 EFNA1 ORMDL3 ORMDL3 TCP1 TCP1 KIFAP3 KIFAP3 LYN LYN SLC7A11 SLC7A11 ST3GAL1 ST3GAL1 NOD2 NOD2 CCL5 CCL5 CCL21 CCL21 CCL19 CCL19 IL7R IL7R BCL2L11 BCL2L11 ZC3H8 ZC3H8 NF1 NF1 P2RX7 P2RX7 ADA ADA AURKB AURKB SELENOS SELENOS PIK3CD PIK3CD MERTK MERTK PTCRA PTCRA IL10 IL10 BLK BLK MEF2C MEF2C FADD FADD SIRT1 SIRT1 CD74 CD74 BBC3 BBC3 LOC111180527 LOC111180527 FNIP1 FNIP1 BCL2 BCL2 GAS6 GAS6 ITPKB ITPKB DOCK8 DOCK8 GIMAP8 GIMAP8 SLC46A2 SLC46A2 CD27 CD27 FOXP1 FOXP1 BCL11B BCL11B IDO1 IDO1 IRS2 IRS2 LGALS3 LGALS3 WNT5A WNT5A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADAM8Disintegrin and metalloproteinase domain-containing protein 8 isoform X1. (838 aa)
ARG2Arginase. (354 aa)
ANXA1Annexin. (346 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (823 aa)
BMP4Bone morphogenetic protein 4 isoform X2. (408 aa)
LOC111169978Von Hippel-Lindau disease tumor suppressor. (166 aa)
PDCD1Programmed cell death protein 1 isoform X1. (288 aa)
PRELID1PRELI domain-containing protein 1, mitochondrial. (219 aa)
CXCL12Stromal cell-derived factor 1 isoform X1; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
PRKCQProtein kinase C. (665 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
AXLLOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO. (887 aa)
BCL10B-cell lymphoma/leukemia 10. (233 aa)
FCARImmunoglobulin alpha Fc receptor isoform X1. (290 aa)
BCL3B-cell lymphoma 3 protein. (454 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2 isoform X1. (1651 aa)
NOC2LNucleolar complex protein 2 homolog isoform X1. (738 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (877 aa)
HCLS1Hematopoietic lineage cell-specific protein. (481 aa)
EFNA1ephrin-A1 isoform X3; Belongs to the ephrin family. (211 aa)
ORMDL3ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
TCP1T-complex protein 1 subunit alpha. (556 aa)
KIFAP3Kinesin-associated protein 3 isoform X1. (793 aa)
LYNTyrosine-protein kinase. (518 aa)
SLC7A11Cystine/glutamate transporter isoform X1. (520 aa)
ST3GAL1CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (342 aa)
NOD2Nucleotide-binding oligomerization domain-containing protein 2 isoform X1. (1086 aa)
CCL5C-C motif chemokine. (91 aa)
CCL21C-C motif chemokine 21 isoform X1. (131 aa)
CCL19C-C motif chemokine. (159 aa)
IL7RInterleukin-7 receptor subunit alpha isoform X1. (459 aa)
BCL2L11Bcl-2-like protein 11 isoform X1. (288 aa)
ZC3H8Zinc finger CCCH domain-containing protein 8 isoform X1. (308 aa)
NF1Neurofibromin isoform X1. (2873 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
ADAAdenosine deaminase isoform X1. (416 aa)
AURKBAurora kinase B isoform X1; Belongs to the protein kinase superfamily. (345 aa)
SELENOSSelenoprotein S isoform X1. (191 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (919 aa)
MERTKTyrosine-protein kinase Mer. (999 aa)
PTCRALOW QUALITY PROTEIN: pre T-cell antigen receptor alpha. (315 aa)
IL10Interleukin-10. (178 aa)
BLKTyrosine-protein kinase. (501 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X6. (483 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (735 aa)
CD74HLA class II histocompatibility antigen gamma chain isoform X1. (278 aa)
BBC3Bcl-2-binding component 3. (193 aa)
LOC111180527Galectin. (201 aa)
FNIP1Folliculin-interacting protein 1 isoform X1. (1165 aa)
BCL2Apoptosis regulator Bcl-2. (233 aa)
GAS6Growth arrest-specific protein 6. (671 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (941 aa)
DOCK8Dedicator of cytokinesis protein 8 isoform X1; Belongs to the DOCK family. (2098 aa)
GIMAP8GTPase IMAP family member 8. (692 aa)
SLC46A2Thymic stromal cotransporter homolog. (475 aa)
CD27CD27 antigen isoform X1. (251 aa)
FOXP1Forkhead box protein P1 isoform X1. (673 aa)
BCL11BB-cell lymphoma/leukemia 11B isoform X1. (903 aa)
IDO1Indoleamine 2,3-dioxygenase 1 isoform X1. (410 aa)
IRS2Insulin receptor substrate 2. (1347 aa)
LGALS3Galectin. (256 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (458 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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