38 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BCL11B	B-cell lymphoma/leukemia 11B isoform X1. (903 aa)
	MERTK	Tyrosine-protein kinase Mer. (999 aa)
	SELENOS	Selenoprotein S isoform X1. (191 aa)
	NOC2L	Nucleolar complex protein 2 homolog isoform X1. (738 aa)
	IL7R	Interleukin-7 receptor subunit alpha isoform X1. (459 aa)
	ADA	Adenosine deaminase isoform X1. (416 aa)
	AURKB	Aurora kinase B isoform X1; Belongs to the protein kinase superfamily. (345 aa)
	FADD	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa)
	CD74	HLA class II histocompatibility antigen gamma chain isoform X1. (278 aa)
	BCL2	Apoptosis regulator Bcl-2. (233 aa)
	BCL3	B-cell lymphoma 3 protein. (454 aa)
	BCL10	B-cell lymphoma/leukemia 10. (233 aa)
	AXL	LOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO. (887 aa)
	PRKCQ	Protein kinase C. (665 aa)
	PTCRA	LOW QUALITY PROTEIN: pre T-cell antigen receptor alpha. (315 aa)
	GAS6	Growth arrest-specific protein 6. (671 aa)
	ITPKB	Kinase; Belongs to the inositol phosphokinase (IPK) family. (941 aa)
	DOCK8	Dedicator of cytokinesis protein 8 isoform X1; Belongs to the DOCK family. (2098 aa)
	SLC46A2	Thymic stromal cotransporter homolog. (475 aa)
	CD27	CD27 antigen isoform X1. (251 aa)
	FOXP1	Forkhead box protein P1 isoform X1. (673 aa)
	IDO1	Indoleamine 2,3-dioxygenase 1 isoform X1. (410 aa)
	IRS2	Insulin receptor substrate 2. (1347 aa)
	ARG2	Arginase. (354 aa)
	HIF1A	Hypoxia-inducible factor 1-alpha isoform X1. (823 aa)
	BMP4	Bone morphogenetic protein 4 isoform X2. (408 aa)
	LOC111169978	Von Hippel-Lindau disease tumor suppressor. (166 aa)
	CXCL12	Stromal cell-derived factor 1 isoform X1; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
	GPAM	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (877 aa)
	HCLS1	Hematopoietic lineage cell-specific protein. (481 aa)
	EFNA1	ephrin-A1 isoform X3; Belongs to the ephrin family. (211 aa)
	ORMDL3	ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
	KIFAP3	Kinesin-associated protein 3 isoform X1. (793 aa)
	ST3GAL1	CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (342 aa)
	NOD2	Nucleotide-binding oligomerization domain-containing protein 2 isoform X1. (1086 aa)
	CCL5	C-C motif chemokine. (91 aa)
	CCL21	C-C motif chemokine 21 isoform X1. (131 aa)
	CCL19	C-C motif chemokine. (159 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARG2	IDO1	A0A2Y9N3L2	A0A2Y9NCL9	Arginase.	Indoleamine 2,3-dioxygenase 1 isoform X1.	0.444
AURKB	NOC2L	A0A2Y9PWK8	A0A2Y9Q8T8	Aurora kinase B isoform X1; Belongs to the protein kinase superfamily.	Nucleolar complex protein 2 homolog isoform X1.	0.923
AXL	FADD	A0A2Y9P2K3	A0A2Y9PNL8	LOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.549
AXL	GAS6	A0A2Y9P2K3	A0A2Y9NM07	LOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO.	Growth arrest-specific protein 6.	0.998
BCL10	BCL2	A0A2Y9P3B6	A0A2Y9P9P5	B-cell lymphoma/leukemia 10.	Apoptosis regulator Bcl-2.	0.462
BCL10	NOD2	A0A2Y9P3B6	A0A2Y9LN02	B-cell lymphoma/leukemia 10.	Nucleotide-binding oligomerization domain-containing protein 2 isoform X1.	0.411
BCL10	PRKCQ	A0A2Y9P3B6	A0A2Y9NSM1	B-cell lymphoma/leukemia 10.	Protein kinase C.	0.746
BCL11B	PTCRA	A0A2Y9NFU8	A0A2Y9NR73	B-cell lymphoma/leukemia 11B isoform X1.	LOW QUALITY PROTEIN: pre T-cell antigen receptor alpha.	0.513
BCL2	BCL10	A0A2Y9P9P5	A0A2Y9P3B6	Apoptosis regulator Bcl-2.	B-cell lymphoma/leukemia 10.	0.462
BCL2	FADD	A0A2Y9P9P5	A0A2Y9PNL8	Apoptosis regulator Bcl-2.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.617
BCL2	HIF1A	A0A2Y9P9P5	A0A2Y9MZ41	Apoptosis regulator Bcl-2.	Hypoxia-inducible factor 1-alpha isoform X1.	0.663
CCL19	CCL21	A0A2Y9LCM2	A0A2Y9LF88	C-C motif chemokine.	C-C motif chemokine 21 isoform X1.	0.928
CCL19	CCL5	A0A2Y9LCM2	A0A2Y9LMK7	C-C motif chemokine.	C-C motif chemokine.	0.476
CCL19	CXCL12	A0A2Y9LCM2	A0A2Y9MS30	C-C motif chemokine.	Stromal cell-derived factor 1 isoform X1; Belongs to the intercrine alpha (chemokine CxC) family.	0.885
CCL21	CCL19	A0A2Y9LF88	A0A2Y9LCM2	C-C motif chemokine 21 isoform X1.	C-C motif chemokine.	0.928
CCL21	CCL5	A0A2Y9LF88	A0A2Y9LMK7	C-C motif chemokine 21 isoform X1.	C-C motif chemokine.	0.973
CCL21	CXCL12	A0A2Y9LF88	A0A2Y9MS30	C-C motif chemokine 21 isoform X1.	Stromal cell-derived factor 1 isoform X1; Belongs to the intercrine alpha (chemokine CxC) family.	0.981
CCL5	CCL19	A0A2Y9LMK7	A0A2Y9LCM2	C-C motif chemokine.	C-C motif chemokine.	0.476
CCL5	CCL21	A0A2Y9LMK7	A0A2Y9LF88	C-C motif chemokine.	C-C motif chemokine 21 isoform X1.	0.973
CCL5	CXCL12	A0A2Y9LMK7	A0A2Y9MS30	C-C motif chemokine.	Stromal cell-derived factor 1 isoform X1; Belongs to the intercrine alpha (chemokine CxC) family.	0.976