STRINGSTRING
ITGA4 ITGA4 TEK TEK TNFAIP3 TNFAIP3 RAMP2 RAMP2 ANGPTL4 ANGPTL4 MAPK7 MAPK7 GPER1 GPER1 FASLG FASLG CD40 CD40 CCDC142 CCDC142 KDR KDR SCG2 SCG2 PRKCI PRKCI PDCD4 PDCD4 NFE2L2 NFE2L2 ANO6 ANO6 GAS6 GAS6 BRAF BRAF ABL1 ABL1 GATA3 GATA3 CDH5 CDH5 IL13 IL13 PAK4 PAK4 KRIT1 KRIT1 THBS1 THBS1 ECSCR ECSCR CD248 CD248 NDNF NDNF LOC111185731 LOC111185731 PDPK1 PDPK1 FGB FGB FGG FGG TNF TNF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITGA4Integrin alpha-4 isoform X1; Belongs to the integrin alpha chain family. (1033 aa)
TEKAngiopoietin-1 receptor. (1125 aa)
TNFAIP3Tumor necrosis factor alpha-induced protein 3. (785 aa)
RAMP2Receptor activity-modifying protein 2. (177 aa)
ANGPTL4Angiopoietin-related protein 4. (412 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (775 aa)
GPER1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
FASLGTumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (262 aa)
CD40Tumor necrosis factor receptor superfamily member 5 isoform X1. (284 aa)
CCDC142Coiled-coil domain-containing protein 142 isoform X1. (771 aa)
KDRVascular endothelial growth factor receptor 2 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
SCG2Secretogranin-2. (615 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (707 aa)
PDCD4Programmed cell death protein 4 isoform X1. (469 aa)
NFE2L2Nuclear factor erythroid 2-related factor 2 isoform X1. (622 aa)
ANO6Anoctamin. (951 aa)
GAS6Growth arrest-specific protein 6. (671 aa)
BRAFSerine/threonine-protein kinase B-raf isoform X1. (762 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
CDH5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (782 aa)
IL13Interleukin-13. (131 aa)
PAK4Non-specific serine/threonine protein kinase. (594 aa)
KRIT1Krev interaction trapped protein 1 isoform X1. (736 aa)
THBS1Thrombospondin-1. (1170 aa)
ECSCREndothelial cell-specific chemotaxis regulator isoform X5. (203 aa)
CD248Endosialin. (764 aa)
NDNFProtein NDNF. (568 aa)
LOC111185731C-C motif chemokine. (99 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
FGBFibrinogen beta chain isoform X1. (495 aa)
FGGFibrinogen gamma chain isoform X1. (445 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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