29 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	SLC18A3	Vesicular acetylcholine transporter. (528 aa)
	PCSK4	Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (779 aa)
	FURIN	Furin; Belongs to the peptidase S8 family. (792 aa)
	EPS15L1	Epidermal growth factor receptor substrate 15-like 1 isoform X1. (947 aa)
	FCHO1	F-BAR domain only protein 1. (887 aa)
	REPS1	ralBP1-associated Eps domain-containing protein 1 isoform X1. (802 aa)
	CA1	Carbonic anhydrase 1; Belongs to the alpha-carbonic anhydrase family. (261 aa)
	ADCY8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
	ITSN1	Intersectin-1 isoform X1. (1715 aa)
	AP2S1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	AP2A1	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (1023 aa)
	AP1S1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
	SPHK1	Sphingosine kinase 1 isoform X2. (484 aa)
	FCHO2	F-BAR domain only protein 2 isoform X2. (810 aa)
	ARRB1	Beta-arrestin-1 isoform X1. (430 aa)
	ACKR3	Atypical chemokine receptor 3 isoform X1; Belongs to the G-protein coupled receptor 1 family. (417 aa)
	LRP2	Low-density lipoprotein receptor-related protein 2. (4838 aa)
	AP2M1	AP-2 complex subunit mu isoform X1; Belongs to the adaptor complexes medium subunit family. (435 aa)
	STON1	Stonin-1; Belongs to the Stoned B family. (730 aa)
	CDCP2	CUB domain-containing protein 2. (540 aa)
	EPS15	Epidermal growth factor receptor substrate 15 isoform X1. (902 aa)
	ITSN2	Intersectin-2 isoform X1. (1667 aa)
	SGIP1	SH3-containing GRB2-like protein 3-interacting protein 1 isoform X1. (854 aa)
	CUBN	Cubilin isoform X1. (3620 aa)
	RAB35	Ras-related protein Rab-35 isoform X1. (201 aa)
	AP2A2	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (938 aa)
	SH3BP4	SH3 domain-binding protein 4 isoform X1. (959 aa)
	AP1S3	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (154 aa)
	AP1S2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACKR3	ARRB1	A0A2Y9MS64	A0A2Y9Q1W6	Atypical chemokine receptor 3 isoform X1; Belongs to the G-protein coupled receptor 1 family.	Beta-arrestin-1 isoform X1.	0.810
AP1S1	AP1S2	A0A2Y9PEG3	A0A2Y9MMK1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.945
AP1S1	AP1S3	A0A2Y9PEG3	A0A2Y9MMK2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.934
AP1S1	AP2A1	A0A2Y9PEG3	A0A2Y9PDU9	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.699
AP1S1	AP2A2	A0A2Y9PEG3	A0A2Y9MPY2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.465
AP1S1	AP2M1	A0A2Y9PEG3	A0A2Y9MW21	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit mu isoform X1; Belongs to the adaptor complexes medium subunit family.	0.507
AP1S1	AP2S1	A0A2Y9PEG3	A0A2Y9PCF4	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.434
AP1S2	AP1S1	A0A2Y9MMK1	A0A2Y9PEG3	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.945
AP1S2	AP1S3	A0A2Y9MMK1	A0A2Y9MMK2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.934
AP1S2	AP2A1	A0A2Y9MMK1	A0A2Y9PDU9	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.694
AP1S2	AP2A2	A0A2Y9MMK1	A0A2Y9MPY2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.448
AP1S2	AP2M1	A0A2Y9MMK1	A0A2Y9MW21	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit mu isoform X1; Belongs to the adaptor complexes medium subunit family.	0.512
AP1S2	AP2S1	A0A2Y9MMK1	A0A2Y9PCF4	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.419
AP1S3	AP1S1	A0A2Y9MMK2	A0A2Y9PEG3	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.934
AP1S3	AP1S2	A0A2Y9MMK2	A0A2Y9MMK1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.934
AP1S3	AP2A1	A0A2Y9MMK2	A0A2Y9PDU9	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.727
AP1S3	AP2A2	A0A2Y9MMK2	A0A2Y9MPY2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.413
AP1S3	AP2M1	A0A2Y9MMK2	A0A2Y9MW21	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit mu isoform X1; Belongs to the adaptor complexes medium subunit family.	0.512
AP1S3	AP2S1	A0A2Y9MMK2	A0A2Y9PCF4	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.419
AP2A1	AP1S1	A0A2Y9PDU9	A0A2Y9PEG3	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.699