STRINGSTRING
MIF MIF CCL19 CCL19 ATPIF1 ATPIF1 WNT4 WNT4 RTN4R RTN4R IGSF21 IGSF21 CD40LG CD40LG PLA2G1B PLA2G1B ABCG1 ABCG1 TEK TEK CX3CL1 CX3CL1 PRND PRND EMP2 EMP2 INTU INTU ASTN1 ASTN1 CD209 CD209 CCR10 CCR10 CLEC17A CLEC17A PCSK6 PCSK6 ENPP3 ENPP3 CD244 CD244 TIGIT TIGIT SLAMF9 SLAMF9 MCAM MCAM CXCR3 CXCR3 CCR6 CCR6 RTBDN RTBDN TGFA TGFA ENPP1 ENPP1 BMPR1A BMPR1A IZUMO1R IZUMO1R HFE HFE SELE SELE PDGFA PDGFA CX3CR1 CX3CR1 ADAM15 ADAM15 FCER1A FCER1A THY1 THY1 TMEM123 TMEM123 CD80 CD80 ITGA2B ITGA2B FOLR1 FOLR1 LOC111170572 LOC111170572 IL2RG IL2RG TMEM102 TMEM102 NOTCH4 NOTCH4 CD86 CD86 L1CAM L1CAM SERPINE2 SERPINE2 LOC111171320 LOC111171320 LOC111171403 LOC111171403 LOC111170649 LOC111170649 ACKR3 ACKR3 LOC111172230 LOC111172230 NRROS NRROS LRP2 LRP2 FGF22 FGF22 FOLR2 FOLR2 LCT LCT BGN BGN LOC111171171 LOC111171171 AAMP AAMP CPM CPM CD63 CD63 LOC111174480 LOC111174480 GHSR GHSR CD274 CD274 SDC1 SDC1 PCSK9 PCSK9 MPL MPL LOC111176754 LOC111176754 CD27 CD27 RTP1 RTP1 CCR2 CCR2 APP APP LOC111176714 LOC111176714 CLEC9A CLEC9A HSPA5 HSPA5 NPTN NPTN SEMA7A SEMA7A LPAR1 LPAR1 TREML1 TREML1 VEGFA VEGFA SRPX2 SRPX2 LOC111177076 LOC111177076 LOC111178963 LOC111178963 TMX3 TMX3 P2RY12 P2RY12 CD58 CD58 FLT3LG FLT3LG CD79A CD79A AXL AXL WNT2B WNT2B WNT2 WNT2 FZD6 FZD6 TGFB1 TGFB1 NECTIN2 NECTIN2 PVR PVR GUSB GUSB CD19 CD19 CYTH3 CYTH3 LOC111182106 LOC111182106 SPN SPN ITGAM ITGAM HBEGF HBEGF HPN HPN CDH2 CDH2 TYROBP TYROBP GIF GIF HAVCR2 HAVCR2 EFNA5 EFNA5 CYTH1 CYTH1 CD34 CD34 LRRC32 LRRC32 LRP4 LRP4 FAM234A FAM234A FZD4 FZD4 CD180 CD180 IL2RB IL2RB LOC111185435 LOC111185435 LOC111185436 LOC111185436 SULF1 SULF1 AREG AREG EPHA2 EPHA2 ADRA2B ADRA2B CDH4 CDH4 STAB2 STAB2 TGFBR1 TGFBR1 SMIM1 SMIM1 LOC111187154 LOC111187154 CD200 CD200
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MIFMacrophage migration inhibitory factor. (115 aa)
CCL19C-C motif chemokine. (159 aa)
ATPIF1ATPase inhibitor, mitochondrial. (107 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
RTN4RReticulon-4 receptor. (481 aa)
IGSF21Immunoglobulin superfamily member 21 isoform X1. (468 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
PLA2G1BPhospholipase A(2). (160 aa)
ABCG1ATP-binding cassette sub-family G member 1 isoform X1. (693 aa)
TEKAngiopoietin-1 receptor. (1125 aa)
CX3CL1Fractalkine. (469 aa)
PRNDPrion-like protein doppel. (178 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
INTUProtein inturned isoform X1. (934 aa)
ASTN1Astrotactin-1 isoform X1. (1302 aa)
CD209CD209 antigen. (279 aa)
CCR10C-C chemokine receptor type 10; Belongs to the G-protein coupled receptor 1 family. (376 aa)
CLEC17AC-type lectin domain family 17, member A isoform X1. (334 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6 isoform X1; Belongs to the peptidase S8 family. (967 aa)
ENPP3Ectonucleotide pyrophosphatase/phosphodiesterase family member 3. (900 aa)
CD244Natural killer cell receptor 2B4. (369 aa)
TIGITT-cell immunoreceptor with Ig and ITIM domains. (243 aa)
SLAMF9LOW QUALITY PROTEIN: SLAM family member 9. (289 aa)
MCAMCell surface glycoprotein MUC18 isoform X1. (638 aa)
CXCR3C-X-C chemokine receptor type 3; Belongs to the G-protein coupled receptor 1 family. (366 aa)
CCR6C-C chemokine receptor type 6; Belongs to the G-protein coupled receptor 1 family. (375 aa)
RTBDNRetbindin isoform X1. (250 aa)
TGFAProtransforming growth factor alpha isoform X1. (176 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 isoform X1. (925 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
IZUMO1RSperm-egg fusion protein Juno. (269 aa)
HFEHereditary hemochromatosis protein isoform X1; Belongs to the MHC class I family. (356 aa)
SELEE-selectin. (531 aa)
PDGFAPlatelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (196 aa)
CX3CR1CX3C chemokine receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (475 aa)
ADAM15Disintegrin and metalloproteinase domain-containing protein 15 isoform X1. (866 aa)
FCER1AHigh affinity immunoglobulin epsilon receptor subunit alpha isoform X1. (258 aa)
THY1Thy-1 membrane glycoprotein. (161 aa)
TMEM123Porimin. (251 aa)
CD80T-lymphocyte activation antigen CD80 isoform X1. (295 aa)
ITGA2BIntegrin alpha-IIb; Belongs to the integrin alpha chain family. (1034 aa)
FOLR1Folate receptor alpha. (251 aa)
LOC111170572Folate receptor alpha. (257 aa)
IL2RGCytokine receptor common subunit gamma isoform X1. (381 aa)
TMEM102LOW QUALITY PROTEIN: transmembrane protein 102. (506 aa)
NOTCH4Neurogenic locus notch homolog protein 4 isoform X1. (1993 aa)
CD86T-lymphocyte activation antigen CD86 isoform X1. (344 aa)
L1CAMNeural cell adhesion molecule L1. (1257 aa)
SERPINE2Glia-derived nexin isoform X2; Belongs to the serpin family. (397 aa)
LOC111171320Mucin-16-like. (855 aa)
LOC111171403LOW QUALITY PROTEIN: transmembrane protein 102-like. (288 aa)
LOC111170649MHC class I polypeptide-related sequence B-like isoform X1. (256 aa)
ACKR3Atypical chemokine receptor 3 isoform X1; Belongs to the G-protein coupled receptor 1 family. (417 aa)
LOC111172230Deleted in malignant brain tumors 1 protein isoform X1. (684 aa)
NRROSNegative regulator of reactive oxygen species isoform X1. (699 aa)
LRP2Low-density lipoprotein receptor-related protein 2. (4838 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
FOLR2Folate receptor beta. (253 aa)
LCTLactase-phlorizin hydrolase. (1928 aa)
BGNBiglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (369 aa)
LOC111171171Integrin alpha-M-like. (296 aa)
AAMPAngio-associated migratory cell protein isoform X1. (435 aa)
CPMCarboxypeptidase M. (443 aa)
CD63Tetraspanin. (237 aa)
LOC111174480C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (352 aa)
GHSRGrowth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
CD274Programmed cell death 1 ligand 1 isoform X2. (312 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (310 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9 isoform X1. (692 aa)
MPLThrombopoietin receptor. (645 aa)
LOC111176754C-type lectin domain family 7 member A-like isoform X1. (244 aa)
CD27CD27 antigen isoform X1. (251 aa)
RTP1Receptor-transporting protein 1. (263 aa)
CCR2C-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family. (373 aa)
APPAmyloid beta A4 protein isoform X1. (767 aa)
LOC111176714Scavenger receptor cysteine-rich type 1 protein M130 isoform X1. (1115 aa)
CLEC9AC-type lectin domain family 9 member A isoform X1. (266 aa)
HSPA578 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family. (655 aa)
NPTNNeuroplastin isoform X1. (398 aa)
SEMA7Asemaphorin-7A; Belongs to the semaphorin family. (665 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
TREML1Trem-like transcript 1 protein isoform X1. (315 aa)
VEGFAVascular endothelial growth factor A isoform X1; Belongs to the PDGF/VEGF growth factor family. (214 aa)
SRPX2Sushi repeat-containing protein SRPX2. (465 aa)
LOC111177076Ficolin-2-like isoform X1. (326 aa)
LOC111178963LOW QUALITY PROTEIN: butyrophilin-like protein 1. (513 aa)
TMX3Protein disulfide-isomerase TMX3 isoform X1. (454 aa)
P2RY12P2Y purinoceptor 12. (339 aa)
CD58Lymphocyte function-associated antigen 3 isoform X1. (242 aa)
FLT3LGFms-related tyrosine kinase 3 ligand isoform X1. (328 aa)
CD79AB-cell antigen receptor complex-associated protein alpha chain. (223 aa)
AXLLOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO. (887 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (397 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
FZD6Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
NECTIN2Nectin-2 isoform X1. (539 aa)
PVRPoliovirus receptor isoform X1. (415 aa)
GUSBBeta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. (652 aa)
CD19B-lymphocyte antigen CD19 isoform X1. (570 aa)
CYTH3Cytohesin-3 isoform X1. (400 aa)
LOC111182106Integrin alpha-X-like isoform X1; Belongs to the integrin alpha chain family. (1210 aa)
SPNLeukosialin. (411 aa)
ITGAMIntegrin alpha-M; Belongs to the integrin alpha chain family. (872 aa)
HBEGFProheparin-binding EGF-like growth factor. (208 aa)
HPNSerine protease hepsin isoform X1; Belongs to the peptidase S1 family. (599 aa)
CDH2Cadherin-2 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
TYROBPTYRO protein tyrosine kinase-binding protein isoform X1. (126 aa)
GIFGastric intrinsic factor. (424 aa)
HAVCR2Hepatitis A virus cellular receptor 2 isoform X1. (375 aa)
EFNA5ephrin-A5 isoform X1; Belongs to the ephrin family. (228 aa)
CYTH1Cytohesin-1 isoform X1. (410 aa)
CD34Hematopoietic progenitor cell antigen CD34 isoform X1. (384 aa)
LRRC32Leucine-rich repeat-containing protein 32 isoform X1. (676 aa)
LRP4Low-density lipoprotein receptor-related protein 4. (1905 aa)
FAM234AProtein FAM234A isoform X1. (552 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
CD180CD180 antigen. (661 aa)
IL2RBInterleukin-2 receptor subunit beta isoform X1. (595 aa)
LOC111185435Tumor necrosis factor receptor superfamily member 10A-like isoform X1. (454 aa)
LOC111185436Tumor necrosis factor receptor superfamily member 10B-like isoform X1. (456 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (882 aa)
AREGAmphiregulin isoform X1. (254 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
ADRA2Balpha-2B adrenergic receptor. (446 aa)
CDH4Cadherin-4 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (914 aa)
STAB2Stabilin-2 isoform X1. (2663 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
SMIM1Small integral membrane protein 1. (78 aa)
LOC111187154Ephrin type-A receptor 2-like. (171 aa)
CD200OX-2 membrane glycoprotein. (267 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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