(38 nodes) DNA packaging complex network (Delphinapterus leucas)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	VPS72	Vacuolar protein sorting-associated protein 72 homolog. (364 aa)
	LOC111168543	Uncharacterized protein LOC111168543; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (333 aa)
	LOC111168523	Histone H2B; Belongs to the histone H2B family. (126 aa)
	TNP1	Spermatid nuclear transition protein 1. (55 aa)
	MORF4L2	Mortality factor 4-like protein 2. (288 aa)
	SMC1A	Structural maintenance of chromosomes protein. (1233 aa)
	SMC3	Structural maintenance of chromosomes protein. (1217 aa)
	NCAPG	Condensin complex subunit 3. (1009 aa)
	SPC25	Kinetochore protein Spc25. (226 aa)
	YEATS4	YEATS domain-containing protein 4. (227 aa)
	ARID2	AT-rich interactive domain-containing protein 2. (1836 aa)
	SMC4	Structural maintenance of chromosomes protein. (1288 aa)
	NCAPG2	Condensin-2 complex subunit G2 isoform X1. (1140 aa)
	BCL11B	B-cell lymphoma/leukemia 11B isoform X1. (903 aa)
	NCAPD2	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1400 aa)
	CENPA	Histone H3-like centromeric protein A. (138 aa)
	BICRA	BRD4-interacting chromatin-remodeling complex-associated protein isoform X1. (1573 aa)
	BCL7B	B-cell CLL/lymphoma 7 protein family member B isoform X1. (202 aa)
	SPHK2	Sphingosine kinase 2 isoform X1. (655 aa)
	SS18	Protein SSXT isoform X1. (418 aa)
	KAT5	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
	ACTL6B	Actin-like protein 6B isoform X1; Belongs to the actin family. (476 aa)
	BCL7C	B-cell CLL/lymphoma 7 protein family member C isoform X1. (217 aa)
	GLYR1	Putative oxidoreductase GLYR1. (553 aa)
	MRGBP	MRG/MORF4L-binding protein isoform X1. (255 aa)
	BCL7A	B-cell CLL/lymphoma 7 protein family member A isoform X1. (231 aa)
	NCAPH2	Condensin-2 complex subunit H2 isoform X1. (679 aa)
	NCAPH	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (735 aa)
	BCL11A	B-cell lymphoma/leukemia 11A isoform X1. (888 aa)
	SMC2	Structural maintenance of chromosomes protein. (1191 aa)
	SMARCA4	Transcription activator BRG1 isoform X4. (1648 aa)
	LOC111166433	Spermatid-specific linker histone H1-like protein. (175 aa)
	SMARCE1	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E, member 1. (411 aa)
	NCAPD3	Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1510 aa)
	MBTD1	MBT domain-containing protein 1 isoform X1. (654 aa)
	LOC111168525	Histone H2B; Belongs to the histone H2B family. (126 aa)
	LOC111168521	Histone H2A; Belongs to the histone H2A family. (130 aa)
	LOC111167415	Histone H2A; Belongs to the histone H2A family. (143 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTL6B	ARID2	A0A2Y9PLR6	A0A2Y9N9H8	Actin-like protein 6B isoform X1; Belongs to the actin family.	AT-rich interactive domain-containing protein 2.	0.928
ACTL6B	BCL7A	A0A2Y9PLR6	A0A2Y9Q7Z2	Actin-like protein 6B isoform X1; Belongs to the actin family.	B-cell CLL/lymphoma 7 protein family member A isoform X1.	0.649
ACTL6B	BCL7B	A0A2Y9PLR6	A0A2Y9PCS1	Actin-like protein 6B isoform X1; Belongs to the actin family.	B-cell CLL/lymphoma 7 protein family member B isoform X1.	0.541
ACTL6B	BCL7C	A0A2Y9PLR6	A0A2Y9PMM9	Actin-like protein 6B isoform X1; Belongs to the actin family.	B-cell CLL/lymphoma 7 protein family member C isoform X1.	0.431
ACTL6B	CENPA	A0A2Y9PLR6	A0A2Y9NKZ2	Actin-like protein 6B isoform X1; Belongs to the actin family.	Histone H3-like centromeric protein A.	0.535
ACTL6B	KAT5	A0A2Y9PLR6	A0A2Y9PJP2	Actin-like protein 6B isoform X1; Belongs to the actin family.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.670
ACTL6B	LOC111168543	A0A2Y9PLR6	A0A2Y9MG52	Actin-like protein 6B isoform X1; Belongs to the actin family.	Uncharacterized protein LOC111168543; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.535
ACTL6B	MORF4L2	A0A2Y9PLR6	A0A2Y9MQZ0	Actin-like protein 6B isoform X1; Belongs to the actin family.	Mortality factor 4-like protein 2.	0.714
ACTL6B	MRGBP	A0A2Y9PLR6	A0A2Y9Q709	Actin-like protein 6B isoform X1; Belongs to the actin family.	MRG/MORF4L-binding protein isoform X1.	0.750
ACTL6B	SMARCA4	A0A2Y9PLR6	A0A2Y9LVE7	Actin-like protein 6B isoform X1; Belongs to the actin family.	Transcription activator BRG1 isoform X4.	0.961
ACTL6B	SMARCE1	A0A2Y9PLR6	A0A2Y9LX12	Actin-like protein 6B isoform X1; Belongs to the actin family.	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E, member 1.	0.966
ACTL6B	SS18	A0A2Y9PLR6	A0A2Y9PH44	Actin-like protein 6B isoform X1; Belongs to the actin family.	Protein SSXT isoform X1.	0.426
ACTL6B	VPS72	A0A2Y9PLR6	A0A2Y9MFX1	Actin-like protein 6B isoform X1; Belongs to the actin family.	Vacuolar protein sorting-associated protein 72 homolog.	0.772
ACTL6B	YEATS4	A0A2Y9PLR6	A0A2Y9N7A1	Actin-like protein 6B isoform X1; Belongs to the actin family.	YEATS domain-containing protein 4.	0.772
ARID2	ACTL6B	A0A2Y9N9H8	A0A2Y9PLR6	AT-rich interactive domain-containing protein 2.	Actin-like protein 6B isoform X1; Belongs to the actin family.	0.928
ARID2	BCL11B	A0A2Y9N9H8	A0A2Y9NFU8	AT-rich interactive domain-containing protein 2.	B-cell lymphoma/leukemia 11B isoform X1.	0.487
ARID2	BCL7A	A0A2Y9N9H8	A0A2Y9Q7Z2	AT-rich interactive domain-containing protein 2.	B-cell CLL/lymphoma 7 protein family member A isoform X1.	0.732
ARID2	BCL7B	A0A2Y9N9H8	A0A2Y9PCS1	AT-rich interactive domain-containing protein 2.	B-cell CLL/lymphoma 7 protein family member B isoform X1.	0.730
ARID2	BCL7C	A0A2Y9N9H8	A0A2Y9PMM9	AT-rich interactive domain-containing protein 2.	B-cell CLL/lymphoma 7 protein family member C isoform X1.	0.814
ARID2	BICRA	A0A2Y9N9H8	A0A2Y9P469	AT-rich interactive domain-containing protein 2.	BRD4-interacting chromatin-remodeling complex-associated protein isoform X1.	0.573