STRINGSTRING
SSTR2 SSTR2 PMP22 PMP22 SYK SYK ITGA2B ITGA2B GPR156 GPR156 ITGB8 ITGB8 CD40 CD40 GRIA3 GRIA3 CD247 CD247 IL6R IL6R LOC111181964 LOC111181964 ITGAL ITGAL PRF1 PRF1 CNIH2 CNIH2 CACNG4 CACNG4 TSPAN32 TSPAN32 CD6 CD6 SCP2D1 SCP2D1 CSF2RB CSF2RB RAMP3 RAMP3 TRAF5 TRAF5 MCMDC2 MCMDC2 ITGAE ITGAE IL13RA1 IL13RA1 HTR3B HTR3B LRRTM4 LRRTM4 BMPR1A BMPR1A CHRNB2 CHRNB2 GABBR1 GABBR1 CSF2RA CSF2RA GRIA4 GRIA4 ITGA3 ITGA3 ERBB2 ERBB2 GRIK4 GRIK4 LYN LYN LOC111166705 LOC111166705 INSRR INSRR IL12RB1 IL12RB1 HTR3A HTR3A CD3E CD3E IL27RA IL27RA POLN POLN CD3G CD3G CD3D CD3D RAMP2 RAMP2 GRM1 GRM1 LOC111166561 LOC111166561 ACVR2B ACVR2B IL20RA IL20RA INSR INSR SDCBP SDCBP LOC111186752 LOC111186752 SSTR5 SSTR5 CHRNA2 CHRNA2 ADAM28 ADAM28 OSMR OSMR IL6ST IL6ST IL18R1 IL18R1 LOC111187417 LOC111187417 LOC111186089 LOC111186089 IGF1R IGF1R SSTR3 SSTR3 BHLHE23 BHLHE23 ITGA1 ITGA1 TPD52 TPD52 TGFBR2 TGFBR2 ITGA9 ITGA9 GRIK2 GRIK2 GRIN2A GRIN2A NIPAL3 NIPAL3 IFNLR1 IFNLR1 GP1BB GP1BB RASD2 RASD2 GABBR2 GABBR2 DIABLO DIABLO GRIN3A GRIN3A TGFBR1 TGFBR1 IL18RAP IL18RAP IL1R1 IL1R1 IL1RL1 IL1RL1 LOC111162624 LOC111162624 GRIK3 GRIK3 CCR9 CCR9 CHRNB4 CHRNB4 ITGA11 ITGA11 EMILIN1 EMILIN1 LOC111173418 LOC111173418 ACVR1C ACVR1C GRIK1 GRIK1 ACVR1 ACVR1 RAMP1 RAMP1 CHRNA5 CHRNA5 CHRNA7 CHRNA7 COL27A1 COL27A1 GRIN2B GRIN2B ITGA8 ITGA8 PTCRA PTCRA CNIH3 CNIH3 TLR6 TLR6 CHRNA10 CHRNA10 GRIN3B GRIN3B ANGPTL2 ANGPTL2 GNAT1 GNAT1 CD27 CD27 GRIN1 GRIN1 ITGA10 ITGA10 TRAF3 TRAF3 LOC111175786 LOC111175786 ITGA6 ITGA6 ACVR1B ACVR1B ITGA7 ITGA7 IL5RA IL5RA AMHR2 AMHR2 ITGB6 ITGB6 HTR2B HTR2B CHRNA6 CHRNA6 ITGB7 ITGB7 ERBB3 ERBB3 SSTR1 SSTR1 LOC111171171 LOC111171171 TNS2 TNS2 CHRNB3 CHRNB3 IL1RL2 IL1RL2 CACNG2 CACNG2 ITGB1 ITGB1 COL24A1 COL24A1 NIPAL2 NIPAL2 GRIN2D GRIN2D CD79A CD79A GRIK5 GRIK5 IL23R IL23R GP6 GP6 GRIA2 GRIA2 BMPR1B BMPR1B CD2 CD2 CACNG8 CACNG8 TFR2 TFR2 CD226 CD226 LOC111182106 LOC111182106 ACVRL1 ACVRL1 IRS2 IRS2 AASDH AASDH VWC2L VWC2L ITGAV ITGAV ITGA4 ITGA4 CHRNA9 CHRNA9 NPNT NPNT LOC111171159 LOC111171159 ITGB5 ITGB5 IRS1 IRS1 SEMA3E SEMA3E BMPR2 BMPR2 CALCRL CALCRL FGFBP1 FGFBP1 LOC111171257 LOC111171257 TLR1 TLR1 DLG3 DLG3 SPN SPN IL4R IL4R ITGAM ITGAM IL9 IL9 CD79B CD79B GRIN2C GRIN2C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SSTR2Somatostatin receptor type 2; Belongs to the G-protein coupled receptor 1 family. (369 aa)
PMP22Peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in the peripheral nervous system; Belongs to the PMP-22/EMP/MP20 family. (160 aa)
SYKTyrosine-protein kinase. (626 aa)
ITGA2BIntegrin alpha-IIb; Belongs to the integrin alpha chain family. (1034 aa)
GPR156Probable G-protein coupled receptor 156. (815 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (767 aa)
CD40Tumor necrosis factor receptor superfamily member 5 isoform X1. (284 aa)
GRIA3Glutamate receptor 3 isoform X1. (888 aa)
CD247T-cell surface glycoprotein CD3 zeta chain isoform X1. (185 aa)
IL6RInterleukin-6 receptor subunit alpha isoform X1. (465 aa)
LOC111181964Uncharacterized protein LOC111181964 isoform X1. (833 aa)
ITGALIntegrin alpha-L; Belongs to the integrin alpha chain family. (1166 aa)
PRF1Perforin-1. (555 aa)
CNIH2Protein cornichon homolog 2 isoform X1. (160 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (375 aa)
TSPAN32Tetraspanin-32 isoform X1; Belongs to the tetraspanin (TM4SF) family. (571 aa)
CD6T-cell differentiation antigen CD6 isoform X1. (675 aa)
SCP2D1SCP2 sterol-binding domain-containing protein 1. (156 aa)
CSF2RBCytokine receptor common subunit beta. (902 aa)
RAMP3Receptor activity-modifying protein 3. (151 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (616 aa)
MCMDC2MCM domain-containing protein 2 isoform X1. (681 aa)
ITGAEIntegrin alpha-E; Belongs to the integrin alpha chain family. (1173 aa)
IL13RA1Interleukin-13 receptor subunit alpha-1. (425 aa)
HTR3B5-hydroxytryptamine receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (448 aa)
LRRTM4Leucine-rich repeat transmembrane neuronal protein 4 isoform X1. (591 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
CHRNB2Neuronal acetylcholine receptor subunit beta-2. (502 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1 isoform X1. (965 aa)
CSF2RAGranulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform X1. (430 aa)
GRIA4Glutamate receptor 4 isoform X1. (902 aa)
ITGA3Integrin alpha-3 isoform X1; Belongs to the integrin alpha chain family. (1068 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
GRIK4Glutamate receptor ionotropic, kainate 4 isoform X1. (957 aa)
LYNTyrosine-protein kinase. (518 aa)
LOC111166705Phylloquinone omega-hydroxylase CYP4F2-like isoform X1; Belongs to the cytochrome P450 family. (524 aa)
INSRRTyrosine-protein kinase receptor. (1301 aa)
IL12RB1Interleukin-12 receptor subunit beta-1 isoform X1. (726 aa)
HTR3A5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (483 aa)
CD3ET-cell surface glycoprotein CD3 epsilon chain. (197 aa)
IL27RAInterleukin-27 receptor subunit alpha isoform X1. (656 aa)
POLNDNA polymerase nu. (901 aa)
CD3GT-cell surface glycoprotein CD3 gamma chain. (178 aa)
CD3DT-cell surface glycoprotein CD3 delta chain. (171 aa)
RAMP2Receptor activity-modifying protein 2. (177 aa)
GRM1Metabotropic glutamate receptor 1. (1195 aa)
LOC111166561LOW QUALITY PROTEIN: docosahexaenoic acid omega-hydroxylase CYP4F3-like. (215 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (553 aa)
IL20RAInterleukin-20 receptor subunit alpha isoform X2. (559 aa)
INSRTyrosine-protein kinase receptor. (1392 aa)
SDCBPSyntenin-1 isoform X3. (301 aa)
LOC111186752T-cell receptor-associated transmembrane adapter 1. (185 aa)
SSTR5Somatostatin receptor type 5; Belongs to the G-protein coupled receptor 1 family. (365 aa)
CHRNA2Neuronal acetylcholine receptor subunit alpha-2 isoform X1. (589 aa)
ADAM28Disintegrin and metalloproteinase domain-containing protein 28. (775 aa)
OSMRoncostatin-M-specific receptor subunit beta isoform X1. (977 aa)
IL6STInterleukin-6 receptor subunit beta. (918 aa)
IL18R1Interleukin-18 receptor 1 isoform X1. (539 aa)
LOC111187417Tyrosine-protein kinase. (612 aa)
LOC111186089LOW QUALITY PROTEIN: syntenin-1-like. (307 aa)
IGF1RTyrosine-protein kinase receptor. (1368 aa)
SSTR3Somatostatin receptor type 3; Belongs to the G-protein coupled receptor 1 family. (425 aa)
BHLHE23Class E basic helix-loop-helix protein 23. (224 aa)
ITGA1Integrin alpha-1; Belongs to the integrin alpha chain family. (1178 aa)
TPD52Tumor protein D52 isoform X1. (247 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
ITGA9Integrin alpha-9; Belongs to the integrin alpha chain family. (1035 aa)
GRIK2Glutamate receptor ionotropic, kainate 2 isoform X2. (908 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A. (1464 aa)
NIPAL3NIPA-like protein 3 isoform X1. (406 aa)
IFNLR1Interferon lambda receptor 1 isoform X1. (535 aa)
GP1BBPlatelet glycoprotein Ib beta chain. (205 aa)
RASD2GTP-binding protein Rhes isoform X2. (266 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (941 aa)
DIABLODiablo homolog, mitochondrial isoform X1. (237 aa)
GRIN3AGlutamate receptor ionotropic, NMDA 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1115 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
IL18RAPInterleukin-18 receptor accessory protein isoform X1. (584 aa)
IL1R1Interleukin-1 receptor type 1 isoform X1. (686 aa)
IL1RL1Interleukin-1 receptor-like 1 isoform X1. (592 aa)
LOC111162624LOW QUALITY PROTEIN: 5-hydroxytryptamine receptor 3C-like; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (347 aa)
GRIK3Glutamate receptor ionotropic, kainate 3 isoform X1. (963 aa)
CCR9C-C chemokine receptor type 9 isoform X1; Belongs to the G-protein coupled receptor 1 family. (369 aa)
CHRNB4Neuronal acetylcholine receptor subunit beta-4. (495 aa)
ITGA11Integrin alpha-11; Belongs to the integrin alpha chain family. (1188 aa)
EMILIN1EMILIN-1. (1015 aa)
LOC111173418LOW QUALITY PROTEIN: 5-hydroxytryptamine receptor 3C-like; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (445 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
GRIK1Glutamate receptor ionotropic, kainate 1 isoform X4. (920 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
RAMP1Receptor activity-modifying protein 1. (148 aa)
CHRNA5Neuronal acetylcholine receptor subunit alpha-5 isoform X1. (475 aa)
CHRNA7Neuronal acetylcholine receptor subunit alpha-7 isoform X2. (499 aa)
COL27A1Collagen alpha-1(XXVII) chain isoform X1. (1846 aa)
GRIN2BGlutamate receptor ionotropic, NMDA 2B. (1499 aa)
ITGA8Integrin alpha-8 isoform X1; Belongs to the integrin alpha chain family. (1062 aa)
PTCRALOW QUALITY PROTEIN: pre T-cell antigen receptor alpha. (315 aa)
CNIH3Protein cornichon homolog 3 isoform X1. (160 aa)
TLR6Toll-like receptor 6; Belongs to the Toll-like receptor family. (797 aa)
CHRNA10Neuronal acetylcholine receptor subunit alpha-10. (382 aa)
GRIN3BGlutamate receptor ionotropic, NMDA 3B isoform X5; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1034 aa)
ANGPTL2Angiopoietin-related protein 2. (493 aa)
GNAT1Guanine nucleotide-binding protein G(T) subunit alpha-1. (350 aa)
CD27CD27 antigen isoform X1. (251 aa)
GRIN1Glutamate receptor ionotropic, NMDA 1 isoform X1. (959 aa)
ITGA10Integrin alpha-10; Belongs to the integrin alpha chain family. (1167 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (572 aa)
LOC111175786LOW QUALITY PROTEIN: putative selection and upkeep of intraepithelial T-cells protein 1 homolog. (365 aa)
ITGA6Integrin alpha-6 isoform X1; Belongs to the integrin alpha chain family. (1091 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (546 aa)
ITGA7Integrin alpha-7 isoform X1; Belongs to the integrin alpha chain family. (1141 aa)
IL5RAInterleukin-5 receptor subunit alpha isoform X1. (417 aa)
AMHR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (597 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (808 aa)
HTR2B5-hydroxytryptamine receptor 2B. (490 aa)
CHRNA6Neuronal acetylcholine receptor subunit alpha-6 isoform X1. (494 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (819 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3. (1338 aa)
SSTR1Somatostatin receptor type 1; Belongs to the G-protein coupled receptor 1 family. (391 aa)
LOC111171171Integrin alpha-M-like. (296 aa)
TNS2Tensin-2 isoform X2. (1415 aa)
CHRNB3Neuronal acetylcholine receptor subunit beta-3. (458 aa)
IL1RL2Interleukin-1 receptor-like 2 isoform X1. (570 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
COL24A1Collagen alpha-1(XXIV) chain. (1707 aa)
NIPAL2NIPA-like protein 2. (383 aa)
GRIN2DLOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2D. (1334 aa)
CD79AB-cell antigen receptor complex-associated protein alpha chain. (223 aa)
GRIK5Glutamate receptor ionotropic, kainate 5 isoform X1. (981 aa)
IL23RInterleukin-23 receptor. (630 aa)
GP6Platelet glycoprotein VI isoform X1. (464 aa)
GRIA2Glutamate receptor 2 isoform X5. (940 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (540 aa)
CD2T-cell surface antigen CD2 isoform X1. (340 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (496 aa)
TFR2Transferrin receptor protein 2 isoform X1. (805 aa)
CD226CD226 antigen. (335 aa)
LOC111182106Integrin alpha-X-like isoform X1; Belongs to the integrin alpha chain family. (1210 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
IRS2Insulin receptor substrate 2. (1347 aa)
AASDHacyl-CoA synthetase family member 4 isoform X1. (1101 aa)
VWC2LVon Willebrand factor C domain-containing protein 2-like. (222 aa)
ITGAVIntegrin alpha-V isoform X2; Belongs to the integrin alpha chain family. (1048 aa)
ITGA4Integrin alpha-4 isoform X1; Belongs to the integrin alpha chain family. (1033 aa)
CHRNA9Neuronal acetylcholine receptor subunit alpha-9. (480 aa)
NPNTNephronectin isoform X3. (595 aa)
LOC111171159LOW QUALITY PROTEIN: acetylcholine receptor subunit beta-like; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (258 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (800 aa)
IRS1Insulin receptor substrate 1. (1248 aa)
SEMA3Esemaphorin-3E; Belongs to the semaphorin family. (775 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
CALCRLCalcitonin gene-related peptide type 1 receptor; Belongs to the G-protein coupled receptor 2 family. (462 aa)
FGFBP1Fibroblast growth factor-binding protein 1. (237 aa)
LOC111171257LOW QUALITY PROTEIN: docosahexaenoic acid omega-hydroxylase CYP4F3-like. (145 aa)
TLR1Toll-like receptor 1; Belongs to the Toll-like receptor family. (796 aa)
DLG3Disks large homolog 3 isoform X1; Belongs to the MAGUK family. (849 aa)
SPNLeukosialin. (411 aa)
IL4RInterleukin-4 receptor subunit alpha isoform X1. (831 aa)
ITGAMIntegrin alpha-M; Belongs to the integrin alpha chain family. (872 aa)
IL9Interleukin-9. (141 aa)
CD79BB-cell antigen receptor complex-associated protein beta chain isoform X1. (230 aa)
GRIN2CGlutamate receptor ionotropic, NMDA 2C isoform X1. (1265 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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