STRINGSTRING
SUSD2 SUSD2 MASP2 MASP2 FBLN7 FBLN7 C7 C7 C6 C6 SEZ6 SEZ6 LOC111184737 LOC111184737 CD55 CD55 VCAN VCAN C4BPB C4BPB LOC111184736 LOC111184736 LOC111184602 LOC111184602 C4BPA C4BPA CR1 CR1 LOC111184601 LOC111184601 APOH APOH CR2 CR2 LOC111184729 LOC111184729 SEZ6L2 SEZ6L2 LOC111179563 LOC111179563 IL2RA IL2RA PAMR1 PAMR1 SUSD1 SUSD1 SUSD4 SUSD4 SRPX2 SRPX2 LOC111177446 LOC111177446 PAPPA PAPPA C1R C1R F13B F13B CFH CFH SVEP1 SVEP1 C1S C1S CSMD2 CSMD2 SNED1 SNED1 C2 C2 CSMD1 CSMD1 MASP1 MASP1 CFB CFB SRPX SRPX SUSD3 SUSD3 SELL SELL SELE SELE SELP SELP GABBR1 GABBR1 TPO TPO BCAN BCAN NCAN NCAN PAPPA2 PAPPA2 CSMD3 CSMD3 SEZ6L SEZ6L SUSD5 SUSD5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SUSD2Sushi domain-containing protein 2. (820 aa)
MASP2Mannan-binding lectin serine protease 2 isoform X1; Belongs to the peptidase S1 family. (686 aa)
FBLN7Fibulin-7. (575 aa)
C7Complement component C7. (843 aa)
C6Complement component C6 isoform X1. (934 aa)
SEZ6Seizure protein 6 homolog isoform X1. (993 aa)
LOC111184737Zona pellucida sperm-binding protein 3 receptor-like. (89 aa)
CD55Complement decay-accelerating factor isoform X1. (590 aa)
VCANVersican core protein isoform X1. (3392 aa)
C4BPBC4b-binding protein beta chain isoform X1. (255 aa)
LOC111184736Apolipoprotein R-like isoform X1. (189 aa)
LOC111184602Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. (367 aa)
C4BPAC4b-binding protein alpha chain isoform X1. (616 aa)
CR1Complement receptor type 1 isoform X1. (1062 aa)
LOC111184601Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. (336 aa)
APOHBeta-2-glycoprotein 1 isoform X1. (345 aa)
CR2Complement receptor type 2 isoform X1. (1471 aa)
LOC111184729Membrane cofactor protein-like isoform X1. (411 aa)
SEZ6L2Seizure 6-like protein 2 isoform X1. (923 aa)
LOC111179563Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. (345 aa)
IL2RAInterleukin-2 receptor subunit alpha. (275 aa)
PAMR1Inactive serine protease PAMR1 isoform X1; Belongs to the peptidase S1 family. (720 aa)
SUSD1Sushi domain-containing protein 1 isoform X1. (748 aa)
SUSD4Sushi domain-containing protein 4 isoform X1. (488 aa)
SRPX2Sushi repeat-containing protein SRPX2. (465 aa)
LOC111177446LOW QUALITY PROTEIN: complement factor H-related protein 2-like. (278 aa)
PAPPAPappalysin-1. (1598 aa)
C1RComplement C1r subcomponent isoform X1; Belongs to the peptidase S1 family. (713 aa)
F13BCoagulation factor XIII B chain. (660 aa)
CFHComplement factor H isoform X1. (1236 aa)
SVEP1Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1. (3572 aa)
C1SComplement C1s subcomponent; Belongs to the peptidase S1 family. (695 aa)
CSMD2CUB and sushi domain-containing protein 2. (3609 aa)
SNED1Sushi, nidogen and EGF-like domain-containing protein 1 isoform X1. (1592 aa)
C2Complement C2 isoform X1; Belongs to the peptidase S1 family. (751 aa)
CSMD1CUB and sushi domain-containing protein 1. (3564 aa)
MASP1Mannan-binding lectin serine protease 1 isoform X1; Belongs to the peptidase S1 family. (739 aa)
CFBComplement factor B isoform X1; Belongs to the peptidase S1 family. (765 aa)
SRPXSushi repeat-containing protein SRPX isoform X1. (462 aa)
SUSD3Sushi domain-containing protein 3 isoform X1. (274 aa)
SELLL-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. (372 aa)
SELEE-selectin. (531 aa)
SELPP-selectin isoform X1. (768 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1 isoform X1. (965 aa)
TPOThyroid peroxidase. (870 aa)
BCANBrevican core protein isoform X1. (909 aa)
NCANNeurocan core protein isoform X1. (1360 aa)
PAPPA2Pappalysin-2. (1790 aa)
CSMD3CUB and sushi domain-containing protein 3 isoform X5. (3707 aa)
SEZ6LSeizure 6-like protein isoform X4. (1034 aa)
SUSD5Sushi domain-containing protein 5. (785 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.