STRINGSTRING
TMEFF1 TMEFF1 C9 C9 CRELD2 CRELD2 EGFLAM EGFLAM FBLN1 FBLN1 FBLN7 FBLN7 EREG EREG EPGN EPGN STAB2 STAB2 EDIL3 EDIL3 AGRN AGRN MASP2 MASP2 MEGF6 MEGF6 HHIP HHIP BTC BTC TMEM8B TMEM8B LOC111162751 LOC111162751 LAMA1 LAMA1 UMOD UMOD NID1 NID1 UMODL1 UMODL1 RELN RELN HSPG2 HSPG2 LAMA4 LAMA4 HGFAC HGFAC SCARF2 SCARF2 TEK TEK F9 F9 ASTN1 ASTN1 FBN3 FBN3 NCAN NCAN COMP COMP CNTNAP1 CNTNAP1 PCSK6 PCSK6 THBS3 THBS3 ADGRE1 ADGRE1 OTOG OTOG BCAN BCAN LOC111167644 LOC111167644 ADGRE5 ADGRE5 JAG1 JAG1 SORL1 SORL1 TNN TNN TGFA TGFA TNR TNR TPO TPO THBS2 THBS2 TENM1 TENM1 LDLR LDLR PEAR1 PEAR1 BMP1 BMP1 SELP SELP NOTCH3 NOTCH3 SCUBE2 SCUBE2 SELE SELE MFGE8 MFGE8 ADAM15 ADAM15 FAT3 FAT3 DLL1 DLL1 TLL1 TLL1 SELL SELL LAMA2 LAMA2 TECTA TECTA LOC111170401 LOC111170401 F12 F12 FBLN2 FBLN2 CRELD1 CRELD1 EGFL8 EGFL8 NOTCH4 NOTCH4 SLIT2 SLIT2 MUC13 MUC13 NPNT NPNT ADAM11 ADAM11 TMEFF2 TMEFF2 HEG1 HEG1 ATRNL1 ATRNL1 TLL2 TLL2 LRP1B LRP1B MASP1 MASP1 ADAM12 ADAM12 VWA2 VWA2 LOC111172293 LOC111172293 LRP2 LRP2 LOC111173009 LOC111173009 FAT1 FAT1 LOC111173535 LOC111173535 DNER DNER PLAT PLAT NID2 NID2 MUC4 MUC4 SNED1 SNED1 WIF1 WIF1 SLIT1 SLIT1 ADAM32 ADAM32 LOC111174264 LOC111174264 LOC111174270 LOC111174270 ADAM23 ADAM23 STAB1 STAB1 ADAM8 ADAM8 NELL2 NELL2 LOC111173305 LOC111173305 MATN3 MATN3 NRG1 NRG1 LOC111173533 LOC111173533 LOC111173536 LOC111173536 HABP2 HABP2 VLDLR VLDLR DLK1 DLK1 TIE1 TIE1 C8A C8A JAG2 JAG2 CELSR3 CELSR3 F10 F10 ADAM9 ADAM9 ADAM2 ADAM2 LRP6 LRP6 EGFL7 EGFL7 NTNG2 NTNG2 MATN1 MATN1 CRB2 CRB2 PTGS1 PTGS1 LAMB2 LAMB2 TDGF1 TDGF1 SVEP1 SVEP1 PCSK5 PCSK5 NRXN1 NRXN1 C1R C1R CNTNAP2 CNTNAP2 MEGF11 MEGF11 LTBP1 LTBP1 FBLN5 FBLN5 ATRAID ATRAID GAS6 GAS6 LAMC3 LAMC3 CRB1 CRB1 LRP8 LRP8 NRXN3 NRXN3 HMCN2 HMCN2 NRG4 NRG4 F7 F7 PROZ PROZ ADGRL4 ADGRL4 PROS1 PROS1 NOTCH1 NOTCH1 ADAM30 ADAM30 CNTNAP4 CNTNAP4 LOC111179522 LOC111179522 TNC TNC SUSD1 SUSD1 MALRD1 MALRD1 PAMR1 PAMR1 NELL1 NELL1 CELSR2 CELSR2 CUBN CUBN MEGF8 MEGF8 MMRN1 MMRN1 MEP1A MEP1A SCUBE3 SCUBE3 LTBP4 LTBP4 DLL3 DLL3 LAMA3 LAMA3 DLK2 DLK2 DLL4 DLL4 MEP1B MEP1B NTNG1 NTNG1 ZAN ZAN LOC111181991 LOC111181991 CCBE1 CCBE1 NOTCH2 NOTCH2 ADAM22 ADAM22 NRG2 NRG2 MATN2 MATN2 HBEGF HBEGF ADAM19 ADAM19 FBN2 FBN2 CNTNAP5 CNTNAP5 OIT3 OIT3 PLAU PLAU FBN1 FBN1 ITGB8 ITGB8 NRXN2 NRXN2 THBS1 THBS1 VWCE VWCE FAT2 FAT2 MEGF10 MEGF10 LTBP3 LTBP3 ITGB4 ITGB4 LAMC2 LAMC2 HMCN1 HMCN1 THBS4 THBS4 TENM4 TENM4 TMEM8A TMEM8A PROC PROC IMPG2 IMPG2 NRG3 NRG3 MATN4 MATN4 LAMB1 LAMB1 LRP5 LRP5 NAGPA NAGPA LAMB4 LAMB4 LAMB3 LAMB3 EFEMP2 EFEMP2 LRP4 LRP4 CD248 CD248 ATRN ATRN LOC111184396 LOC111184396 VCAN VCAN PTGS2 PTGS2 LAMC1 LAMC1 CD93 CD93 THBD THBD VASN VASN SCUBE1 SCUBE1 CELSR1 CELSR1 ADAM28 ADAM28 SLIT3 SLIT3 EFEMP1 EFEMP1 SCARF1 SCARF1 LAMA5 LAMA5 AREG AREG FRAS1 FRAS1 FAT4 FAT4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TMEFF1Tomoregulin-1 isoform X1. (380 aa)
C9Complement component C9. (548 aa)
CRELD2Cysteine-rich with EGF-like domain protein 2 isoform X1. (352 aa)
EGFLAMPikachurin isoform X1. (1025 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (705 aa)
FBLN7Fibulin-7. (575 aa)
EREGProepiregulin. (163 aa)
EPGNEpigen. (153 aa)
STAB2Stabilin-2 isoform X1. (2663 aa)
EDIL3EGF-like repeat and discoidin I-like domain-containing protein 3. (453 aa)
AGRNAgrin isoform X1. (2057 aa)
MASP2Mannan-binding lectin serine protease 2 isoform X1; Belongs to the peptidase S1 family. (686 aa)
MEGF6LOW QUALITY PROTEIN: multiple epidermal growth factor-like domains protein 6. (1534 aa)
HHIPHedgehog-interacting protein isoform X1. (700 aa)
BTCProbetacellulin. (178 aa)
TMEM8BTransmembrane protein 8B isoform X1. (1028 aa)
LOC111162751Disintegrin and metalloproteinase domain-containing protein 1a-like. (839 aa)
LAMA1Laminin subunit alpha-1 isoform X1. (3081 aa)
UMODUromodulin. (643 aa)
NID1Nidogen-1 isoform X1. (1242 aa)
UMODL1Uromodulin-like 1. (1321 aa)
RELNReelin isoform X1. (3460 aa)
HSPG2Basement membrane-specific heparan sulfate proteoglycan core protein isoform X1. (4408 aa)
LAMA4Laminin subunit alpha-4 isoform X1. (1824 aa)
HGFACHepatocyte growth factor activator isoform X1. (702 aa)
SCARF2Scavenger receptor class F member 2 isoform X1. (871 aa)
TEKAngiopoietin-1 receptor. (1125 aa)
F9Coagulation factor IX. (462 aa)
ASTN1Astrotactin-1 isoform X1. (1302 aa)
FBN3Fibrillin-3 isoform X1. (2823 aa)
NCANNeurocan core protein isoform X1. (1360 aa)
COMPCartilage oligomeric matrix protein. (756 aa)
CNTNAP1Contactin-associated protein 1 isoform X1. (1376 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6 isoform X1; Belongs to the peptidase S8 family. (967 aa)
THBS3Thrombospondin-3 isoform X4. (957 aa)
ADGRE1Adhesion G protein-coupled receptor E1; Belongs to the G-protein coupled receptor 2 family. (937 aa)
OTOGOtogelin isoform X1. (3024 aa)
BCANBrevican core protein isoform X1. (909 aa)
LOC111167644Contactin-associated protein-like 3 isoform X1. (1390 aa)
ADGRE5CD97 antigen isoform X1; Belongs to the G-protein coupled receptor 2 family. (856 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1221 aa)
SORL1Sortilin-related receptor isoform X1. (2211 aa)
TNNtenascin-N. (1296 aa)
TGFAProtransforming growth factor alpha isoform X1. (176 aa)
TNRtenascin-R isoform X1. (1358 aa)
TPOThyroid peroxidase. (870 aa)
THBS2Thrombospondin-2. (1171 aa)
TENM1Teneurin-1 isoform X1. (2659 aa)
LDLRLow-density lipoprotein receptor. (857 aa)
PEAR1Platelet endothelial aggregation receptor 1 isoform X1. (1041 aa)
BMP1Metalloendopeptidase. (986 aa)
SELPP-selectin isoform X1. (768 aa)
NOTCH3Neurogenic locus notch homolog protein 3 isoform X1. (2336 aa)
SCUBE2Signal peptide, CUB and EGF-like domain-containing protein 2 isoform X1. (1100 aa)
SELEE-selectin. (531 aa)
MFGE8Lactadherin. (431 aa)
ADAM15Disintegrin and metalloproteinase domain-containing protein 15 isoform X1. (866 aa)
FAT3Protocadherin Fat 3 isoform X1. (4612 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (799 aa)
TLL1Metalloendopeptidase. (1013 aa)
SELLL-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. (372 aa)
LAMA2Laminin subunit alpha-2. (3008 aa)
TECTAAlpha-tectorin isoform X1. (2159 aa)
LOC111170401Protein eyes shut homolog. (1355 aa)
F12LOW QUALITY PROTEIN: coagulation factor XII. (650 aa)
FBLN2Fibulin-2 isoform X1. (1217 aa)
CRELD1Cysteine-rich with EGF-like domain protein 1 isoform X2. (432 aa)
EGFL8Epidermal growth factor-like protein 8 isoform X1. (300 aa)
NOTCH4Neurogenic locus notch homolog protein 4 isoform X1. (1993 aa)
SLIT2Slit homolog 2 protein isoform X1. (1534 aa)
MUC13Mucin-13. (397 aa)
NPNTNephronectin isoform X3. (595 aa)
ADAM11Disintegrin and metalloproteinase domain-containing protein 11 isoform X1. (776 aa)
TMEFF2Tomoregulin-2. (374 aa)
HEG1Protein HEG homolog 1 isoform X1. (1474 aa)
ATRNL1Attractin-like protein 1 isoform X1. (1401 aa)
TLL2Metalloendopeptidase. (1020 aa)
LRP1BLow-density lipoprotein receptor-related protein 1B isoform X1. (4679 aa)
MASP1Mannan-binding lectin serine protease 1 isoform X1; Belongs to the peptidase S1 family. (739 aa)
ADAM12Disintegrin and metalloproteinase domain-containing protein 12 isoform X1. (1422 aa)
VWA2LOW QUALITY PROTEIN: von Willebrand factor A domain-containing protein 2. (774 aa)
LOC111172293Hyaluronan-binding protein 2. (553 aa)
LRP2Low-density lipoprotein receptor-related protein 2. (4838 aa)
LOC111173009LOW QUALITY PROTEIN: disintegrin and metalloproteinase domain-containing protein 20-like. (779 aa)
FAT1Protocadherin Fat 1 isoform X1. (4642 aa)
LOC111173535Disintegrin and metalloproteinase domain-containing protein 18-like. (704 aa)
DNERDelta and Notch-like epidermal growth factor-related receptor. (736 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (565 aa)
NID2Nidogen-2. (1384 aa)
MUC4LOW QUALITY PROTEIN: mucin-4. (1187 aa)
SNED1Sushi, nidogen and EGF-like domain-containing protein 1 isoform X1. (1592 aa)
WIF1Wnt inhibitory factor 1. (379 aa)
SLIT1Slit homolog 1 protein isoform X1. (1534 aa)
ADAM32Disintegrin and metalloproteinase domain-containing protein 32. (758 aa)
LOC111174264EGF-like and EMI domain-containing protein 1. (174 aa)
LOC111174270EGF-like and EMI domain-containing protein 1. (157 aa)
ADAM23Disintegrin and metalloproteinase domain-containing protein 23 isoform X1. (833 aa)
STAB1Stabilin-1 isoform X1. (2596 aa)
ADAM8Disintegrin and metalloproteinase domain-containing protein 8 isoform X1. (838 aa)
NELL2Protein kinase C-binding protein NELL2. (817 aa)
LOC111173305Disintegrin and metalloproteinase domain-containing protein 29-like. (662 aa)
MATN3Matrilin-3. (482 aa)
NRG1Pro-neuregulin-1, membrane-bound isoform isoform X1. (852 aa)
LOC111173533Disintegrin and metalloproteinase domain-containing protein 5-like. (660 aa)
LOC111173536LOW QUALITY PROTEIN: disintegrin and metalloproteinase domain-containing protein 18-like. (737 aa)
HABP2Hyaluronan-binding protein 2. (433 aa)
VLDLRVery low-density lipoprotein receptor isoform X1. (873 aa)
DLK1Protein delta homolog 1 isoform X1. (383 aa)
TIE1Tyrosine-protein kinase receptor Tie-1 isoform X1. (1139 aa)
C8AComplement component C8 alpha chain isoform X1. (589 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1233 aa)
CELSR3Cadherin EGF LAG seven-pass G-type receptor 3 isoform X1; Belongs to the G-protein coupled receptor 2 family. (3322 aa)
F10Coagulation factor X isoform X1. (480 aa)
ADAM9Disintegrin and metalloproteinase domain-containing protein 9 isoform X1. (841 aa)
ADAM2Disintegrin and metalloproteinase domain-containing protein 2. (732 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1614 aa)
EGFL7Epidermal growth factor-like protein 7 isoform X1. (274 aa)
NTNG2netrin-G2 isoform X1. (636 aa)
MATN1Cartilage matrix protein. (495 aa)
CRB2Protein crumbs homolog 2. (1281 aa)
PTGS1Prostaglandin G/H synthase 1 isoform X1. (600 aa)
LAMB2Laminin subunit beta-2 isoform X1. (1812 aa)
TDGF1Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (186 aa)
SVEP1Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1. (3572 aa)
PCSK5Proprotein convertase subtilisin/kexin type 5 isoform X2; Belongs to the peptidase S8 family. (1877 aa)
NRXN1Neurexin-1 isoform X1. (1514 aa)
C1RComplement C1r subcomponent isoform X1; Belongs to the peptidase S1 family. (713 aa)
CNTNAP2Contactin-associated protein-like 2. (1331 aa)
MEGF11Multiple epidermal growth factor-like domains protein 11 isoform X1. (1140 aa)
LTBP1Latent-transforming growth factor beta-binding protein 1 isoform X1. (1711 aa)
FBLN5Fibulin-5 isoform X1. (461 aa)
ATRAIDAll-trans retinoic acid-induced differentiation factor. (229 aa)
GAS6Growth arrest-specific protein 6. (671 aa)
LAMC3Laminin subunit gamma-3. (1577 aa)
CRB1Protein crumbs homolog 1 isoform X1. (1457 aa)
LRP8Low-density lipoprotein receptor-related protein 8 isoform X1. (996 aa)
NRXN3Neurexin 3 isoform X15. (1679 aa)
HMCN2Hemicentin-2 isoform X2. (5072 aa)
NRG4Pro-neuregulin-4, membrane-bound isoform. (116 aa)
F7Coagulation factor VII isoform X1. (447 aa)
PROZVitamin K-dependent protein Z; Belongs to the peptidase S1 family. (709 aa)
ADGRL4Adhesion G protein-coupled receptor L4 isoform X1; Belongs to the G-protein coupled receptor 2 family. (739 aa)
PROS1Vitamin K-dependent protein S. (675 aa)
NOTCH1Neurogenic locus notch homolog protein 1 isoform X1. (2521 aa)
ADAM30LOW QUALITY PROTEIN: disintegrin and metalloproteinase domain-containing protein 30. (758 aa)
CNTNAP4Contactin-associated protein-like 4 isoform X2. (1220 aa)
LOC111179522C-type lectin domain family 18 member A-like isoform X4. (496 aa)
TNCTenascin isoform X1. (2201 aa)
SUSD1Sushi domain-containing protein 1 isoform X1. (748 aa)
MALRD1MAM and LDL-receptor class A domain-containing protein 1. (2150 aa)
PAMR1Inactive serine protease PAMR1 isoform X1; Belongs to the peptidase S1 family. (720 aa)
NELL1Protein kinase C-binding protein NELL1 isoform X1. (810 aa)
CELSR2LOW QUALITY PROTEIN: cadherin EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2918 aa)
CUBNCubilin isoform X1. (3620 aa)
MEGF8LOW QUALITY PROTEIN: multiple epidermal growth factor-like domains protein 8. (2784 aa)
MMRN1Multimerin-1. (1216 aa)
MEP1AMetalloendopeptidase. (780 aa)
SCUBE3Signal peptide, CUB and EGF-like domain-containing protein 3. (864 aa)
LTBP4Latent-transforming growth factor beta-binding protein 4 isoform X1. (1628 aa)
DLL3Delta-like protein 3. (586 aa)
LAMA3Laminin subunit alpha-3 isoform X3. (3335 aa)
DLK2Protein delta homolog 2 isoform X1. (432 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
MEP1BMeprin A subunit. (700 aa)
NTNG1netrin-G1 isoform X1. (582 aa)
ZANZonadhesin. (2288 aa)
LOC111181991LOW QUALITY PROTEIN: mucin-12-like. (373 aa)
CCBE1Collagen and calcium-binding EGF domain-containing protein 1 isoform X1. (407 aa)
NOTCH2Neurogenic locus notch homolog protein 2 isoform X1. (2471 aa)
ADAM22Disintegrin and metalloproteinase domain-containing protein 22 isoform X1. (963 aa)
NRG2Pro-neuregulin-2, membrane-bound isoform isoform X1. (845 aa)
MATN2Matrilin-2 isoform X1. (956 aa)
HBEGFProheparin-binding EGF-like growth factor. (208 aa)
ADAM19Disintegrin and metalloproteinase domain-containing protein 19. (909 aa)
FBN2Fibrillin-2. (2912 aa)
CNTNAP5Contactin-associated protein-like 5 isoform X1. (1307 aa)
OIT3Oncoprotein-induced transcript 3 protein. (546 aa)
PLAUUrokinase-type plasminogen activator. (431 aa)
FBN1Fibrillin-1 isoform X1. (2871 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (767 aa)
NRXN2Neurexin-2-beta isoform X1. (1713 aa)
THBS1Thrombospondin-1. (1170 aa)
VWCEVon Willebrand factor C and EGF domain-containing protein. (946 aa)
FAT2Protocadherin Fat 2. (4352 aa)
MEGF10Multiple epidermal growth factor-like domains protein 10. (1139 aa)
LTBP3Latent-transforming growth factor beta-binding protein 3 isoform X1. (1557 aa)
ITGB4Integrin beta. (1826 aa)
LAMC2Laminin subunit gamma-2. (1191 aa)
HMCN1Hemicentin-1. (5635 aa)
THBS4Thrombospondin-4. (961 aa)
TENM4Teneurin-4 isoform X1. (2864 aa)
TMEM8ATransmembrane protein 8A isoform X1. (793 aa)
PROCVitamin K-dependent protein C. (480 aa)
IMPG2Interphotoreceptor matrix proteoglycan 2 isoform X1. (1282 aa)
NRG3Pro-neuregulin-3, membrane-bound isoform isoform X2. (725 aa)
MATN4Matrilin-4 isoform X1. (624 aa)
LAMB1Laminin subunit beta-1. (1786 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1622 aa)
NAGPAN-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase isoform X1. (602 aa)
LAMB4LOW QUALITY PROTEIN: laminin subunit beta-4. (1767 aa)
LAMB3Laminin subunit beta-3. (1172 aa)
EFEMP2EGF-containing fibulin-like extracellular matrix protein 2 isoform X1. (523 aa)
LRP4Low-density lipoprotein receptor-related protein 4. (1905 aa)
CD248Endosialin. (764 aa)
ATRNAttractin isoform X3. (1489 aa)
LOC111184396Disintegrin and metalloproteinase domain-containing protein 33-like isoform X1. (802 aa)
VCANVersican core protein isoform X1. (3392 aa)
PTGS2Prostaglandin G/H synthase 2. (604 aa)
LAMC1Laminin subunit gamma-1. (1608 aa)
CD93Complement component C1q receptor. (648 aa)
THBDThrombomodulin. (584 aa)
VASNVasorin. (676 aa)
SCUBE1Signal peptide, CUB and EGF-like domain-containing protein 1 isoform X1. (1017 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1 isoform X1; Belongs to the G-protein coupled receptor 2 family. (3038 aa)
ADAM28Disintegrin and metalloproteinase domain-containing protein 28. (775 aa)
SLIT3Slit homolog 3 protein isoform X2. (1523 aa)
EFEMP1EGF-containing fibulin-like extracellular matrix protein 1 isoform X1. (498 aa)
SCARF1Scavenger receptor class F member 1 isoform X1. (870 aa)
LAMA5Laminin subunit alpha-5. (3687 aa)
AREGAmphiregulin isoform X1. (254 aa)
FRAS1Extracellular matrix protein FRAS1 isoform X1. (3956 aa)
FAT4Protocadherin Fat 4. (4981 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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