STRINGSTRING
TEC TEC BMX BMX SYK SYK FES FES OBSCN OBSCN PDGFRA PDGFRA PTK2 PTK2 NTRK1 NTRK1 LYN LYN INSRR INSRR ABL2 ABL2 FGR FGR EPHA8 EPHA8 EPHB2 EPHB2 RET RET FYN FYN FRK FRK TEK TEK INSR INSR EPHA7 EPHA7 PLK4 PLK4 FGFR3 FGFR3 TYK2 TYK2 NTRK2 NTRK2 EGFR EGFR HCK HCK SRC SRC CSF1R CSF1R AATK AATK FER FER PDGFRB PDGFRB ITK ITK EPHB4 EPHB4 LMTK3 LMTK3 LMTK2 LMTK2 YES1 YES1 TYRO3 TYRO3 RYK RYK JAK1 JAK1 PTK2B PTK2B LOC111187417 LOC111187417 TNK1 TNK1 EPHA2 EPHA2 IGF1R IGF1R PTK6 PTK6 TESK1 TESK1 MERTK MERTK MATK MATK ERBB2 ERBB2 JAK3 JAK3 NTRK3 NTRK3 EPHA5 EPHA5 DDR2 DDR2 ROR2 ROR2 ROS1 ROS1 KIT KIT EPHB1 EPHB1 ABL1 ABL1 MET MET MUSK MUSK EPHA1 EPHA1 ROR1 ROR1 LOC111178990 LOC111178990 BTK BTK EPHA3 EPHA3 CSK CSK LCK LCK PEAK1 PEAK1 STYK1 STYK1 MST1R MST1R TESK2 TESK2 TIE1 TIE1 TTN TTN FLT1 FLT1 FLT3 FLT3 FGFR1 FGFR1 PRAG1 PRAG1 PTK7 PTK7 AXL AXL JAK2 JAK2 EPHA4 EPHA4 EPHB3 EPHB3 FLT4 FLT4 TNK2 TNK2 KDR KDR ERBB4 ERBB4 FGFR2 FGFR2 TXK TXK FGFR4 FGFR4 TP53RK TP53RK DDR1 DDR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TECTyrosine-protein kinase. (658 aa)
BMXTyrosine-protein kinase. (692 aa)
SYKTyrosine-protein kinase. (626 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
OBSCNObscurin isoform X1. (7870 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
PTK2Focal adhesion kinase 1 isoform X22; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1116 aa)
NTRK1Tyrosine-protein kinase receptor. (795 aa)
LYNTyrosine-protein kinase. (518 aa)
INSRRTyrosine-protein kinase receptor. (1301 aa)
ABL2Tyrosine-protein kinase. (1174 aa)
FGRTyrosine-protein kinase. (526 aa)
EPHA8Ephrin type-A receptor 8. (1005 aa)
EPHB2Ephrin type-B receptor 2 isoform X1. (987 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1113 aa)
FYNTyrosine-protein kinase. (537 aa)
FRKTyrosine-protein kinase. (513 aa)
TEKAngiopoietin-1 receptor. (1125 aa)
INSRTyrosine-protein kinase receptor. (1392 aa)
EPHA7Ephrin type-A receptor 7 isoform X1. (998 aa)
PLK4Serine/threonine-protein kinase PLK4 isoform X1. (972 aa)
FGFR3Fibroblast growth factor receptor. (805 aa)
TYK2Tyrosine-protein kinase. (1188 aa)
NTRK2Tyrosine-protein kinase receptor. (822 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
HCKTyrosine-protein kinase. (506 aa)
SRCTyrosine-protein kinase. (562 aa)
CSF1RMacrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (961 aa)
AATKSerine/threonine-protein kinase LMTK1 isoform X5. (1442 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa)
ITKTyrosine-protein kinase. (620 aa)
EPHB4Ephrin type-B receptor 4. (987 aa)
LMTK3LOW QUALITY PROTEIN: serine/threonine-protein kinase LMTK3. (1547 aa)
LMTK2Serine/threonine-protein kinase LMTK2 isoform X1. (1497 aa)
YES1Tyrosine-protein kinase. (541 aa)
TYRO3Tyrosine-protein kinase receptor TYRO3 isoform X3. (896 aa)
RYKTyrosine-protein kinase RYK isoform X1. (609 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1015 aa)
LOC111187417Tyrosine-protein kinase. (612 aa)
TNK1Non-receptor tyrosine-protein kinase TNK1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (699 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
IGF1RTyrosine-protein kinase receptor. (1368 aa)
PTK6Non-specific protein-tyrosine kinase. (354 aa)
TESK1Dual specificity testis-specific protein kinase 1 isoform X1. (628 aa)
MERTKTyrosine-protein kinase Mer. (999 aa)
MATKTyrosine-protein kinase. (706 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
JAK3Tyrosine-protein kinase. (1104 aa)
NTRK3Tyrosine-protein kinase receptor. (864 aa)
EPHA5Ephrin type-A receptor 5 isoform X1. (1037 aa)
DDR2Discoidin domain-containing receptor 2. (565 aa)
ROR2Tyrosine-protein kinase transmembrane receptor ROR2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (940 aa)
ROS1Tyrosine-protein kinase receptor. (2348 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
EPHB1Ephrin type-B receptor 1 isoform X1. (984 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
METHepatocyte growth factor receptor isoform X1. (1382 aa)
MUSKMuscle, skeletal receptor tyrosine-protein kinase isoform X1. (879 aa)
EPHA1Ephrin type-A receptor 1 isoform X1. (981 aa)
ROR1Inactive tyrosine-protein kinase transmembrane receptor ROR1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa)
LOC111178990Ephrin type-A receptor 6 isoform X1. (774 aa)
BTKTyrosine-protein kinase. (687 aa)
EPHA3Ephrin type-A receptor 3. (984 aa)
CSKTyrosine-protein kinase. (528 aa)
LCKTyrosine-protein kinase. (509 aa)
PEAK1Pseudopodium-enriched atypical kinase 1. (1745 aa)
STYK1Tyrosine-protein kinase STYK1 isoform X1. (427 aa)
MST1RMacrophage-stimulating protein receptor isoform X1. (1406 aa)
TESK2Dual specificity testis-specific protein kinase 2 isoform X1. (572 aa)
TIE1Tyrosine-protein kinase receptor Tie-1 isoform X1. (1139 aa)
TTNTitin. (32000 aa)
FLT1Vascular endothelial growth factor receptor 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1340 aa)
FLT3Receptor-type tyrosine-protein kinase FLT3 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
FGFR1Fibroblast growth factor receptor. (823 aa)
PRAG1Tyrosine-protein kinase PRAG1 isoform X1. (1404 aa)
PTK7Inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
AXLLOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO. (887 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
EPHA4Ephrin type-A receptor 4 isoform X1. (986 aa)
EPHB3Ephrin type-B receptor 3. (997 aa)
FLT4Vascular endothelial growth factor receptor 3 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1367 aa)
TNK2Activated CDC42 kinase 1 isoform X3; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1086 aa)
KDRVascular endothelial growth factor receptor 2 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
FGFR2Fibroblast growth factor receptor. (841 aa)
TXKTyrosine-protein kinase. (550 aa)
FGFR4Fibroblast growth factor receptor. (801 aa)
TP53RKTP53-regulating kinase isoform X1. (253 aa)
DDR1Tyrosine-protein kinase receptor. (917 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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