STRINGSTRING
PKD1 PKD1 LOC111185769 LOC111185769 ALOX15 ALOX15 PKDREJ PKDREJ LIPC LIPC LIPG LIPG DENND5B DENND5B LOC111172609 LOC111172609 PNLIPRP1 PNLIPRP1 PNLIPRP2 PNLIPRP2 ALOX5 ALOX5 LOXHD1 LOXHD1 DENND5A DENND5A LPL LPL ALOX12 ALOX12 ALOXE3 ALOXE3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PKD1Polycystin-1 isoform X1. (4335 aa)
LOC111185769Arachidonate 15-lipoxygenase B-like. (677 aa)
ALOX15LOW QUALITY PROTEIN: arachidonate 15-lipoxygenase. (663 aa)
PKDREJPolycystic kidney disease and receptor for egg jelly-related protein. (2275 aa)
LIPCHepatic triacylglycerol lipase isoform X1. (510 aa)
LIPGEndothelial lipase. (505 aa)
DENND5BDENN domain-containing protein 5B isoform X1. (1296 aa)
LOC111172609Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (465 aa)
PNLIPRP1Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (467 aa)
PNLIPRP2Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (469 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
LOXHD1Lipoxygenase homology domain-containing protein 1 isoform X1. (2214 aa)
DENND5ADENN domain-containing protein 5A. (1288 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (478 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S-type. (663 aa)
ALOXE3LOW QUALITY PROTEIN: hydroperoxide isomerase ALOXE3. (710 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.