node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
IL6 | IL6R | Q9XT80 | A0A2Y9MCS4 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] | Interleukin-6 receptor subunit alpha isoform X1. | 0.999 |
IL6 | IL6ST | Q9XT80 | A0A2Y9Q671 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] | Interleukin-6 receptor subunit beta. | 0.978 |
IL6 | JAK1 | Q9XT80 | A0A2Y9P436 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] | Tyrosine-protein kinase. | 0.980 |
IL6 | JAK2 | Q9XT80 | A0A2Y9N3T7 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] | Tyrosine-protein kinase. | 0.978 |
IL6 | LOC111187198 | Q9XT80 | A0A2Y9QG58 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.478 |
IL6 | MAPK1 | Q9XT80 | A0A2Y9LEH4 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] | Mitogen-activated protein kinase. | 0.468 |
IL6 | PTPN11 | Q9XT80 | A0A2Y9QEG1 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.478 |
IL6 | TYK2 | Q9XT80 | A0A2Y9LU92 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] | Tyrosine-protein kinase. | 0.760 |
IL6R | IL6 | A0A2Y9MCS4 | Q9XT80 | Interleukin-6 receptor subunit alpha isoform X1. | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] | 0.999 |
IL6R | IL6ST | A0A2Y9MCS4 | A0A2Y9Q671 | Interleukin-6 receptor subunit alpha isoform X1. | Interleukin-6 receptor subunit beta. | 0.976 |
IL6R | JAK1 | A0A2Y9MCS4 | A0A2Y9P436 | Interleukin-6 receptor subunit alpha isoform X1. | Tyrosine-protein kinase. | 0.965 |
IL6R | JAK2 | A0A2Y9MCS4 | A0A2Y9N3T7 | Interleukin-6 receptor subunit alpha isoform X1. | Tyrosine-protein kinase. | 0.968 |
IL6R | LOC111187198 | A0A2Y9MCS4 | A0A2Y9QG58 | Interleukin-6 receptor subunit alpha isoform X1. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.479 |
IL6R | PTPN11 | A0A2Y9MCS4 | A0A2Y9QEG1 | Interleukin-6 receptor subunit alpha isoform X1. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.479 |
IL6R | TYK2 | A0A2Y9MCS4 | A0A2Y9LU92 | Interleukin-6 receptor subunit alpha isoform X1. | Tyrosine-protein kinase. | 0.878 |
IL6ST | IL6 | A0A2Y9Q671 | Q9XT80 | Interleukin-6 receptor subunit beta. | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] | 0.978 |
IL6ST | IL6R | A0A2Y9Q671 | A0A2Y9MCS4 | Interleukin-6 receptor subunit beta. | Interleukin-6 receptor subunit alpha isoform X1. | 0.976 |
IL6ST | JAK1 | A0A2Y9Q671 | A0A2Y9P436 | Interleukin-6 receptor subunit beta. | Tyrosine-protein kinase. | 0.995 |
IL6ST | JAK2 | A0A2Y9Q671 | A0A2Y9N3T7 | Interleukin-6 receptor subunit beta. | Tyrosine-protein kinase. | 0.991 |
IL6ST | PTPN11 | A0A2Y9Q671 | A0A2Y9QEG1 | Interleukin-6 receptor subunit beta. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.607 |