5 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IRS1	Insulin receptor substrate 1. (1248 aa)
	SOS1	Son of sevenless homolog 1 isoform X1. (1333 aa)
	IRS2	Insulin receptor substrate 2. (1347 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	LOC111181964	Uncharacterized protein LOC111181964 isoform X1. (833 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GRB2	IRS1	A0A2Y9PJ90	A0A2Y9MMM9	Growth factor receptor-bound protein 2.	Insulin receptor substrate 1.	0.995
GRB2	IRS2	A0A2Y9PJ90	A0A2Y9NC55	Growth factor receptor-bound protein 2.	Insulin receptor substrate 2.	0.982
GRB2	LOC111181964	A0A2Y9PJ90	A0A2Y9PK20	Growth factor receptor-bound protein 2.	Uncharacterized protein LOC111181964 isoform X1.	0.980
GRB2	SOS1	A0A2Y9PJ90	A0A2Y9N647	Growth factor receptor-bound protein 2.	Son of sevenless homolog 1 isoform X1.	0.999
IRS1	GRB2	A0A2Y9MMM9	A0A2Y9PJ90	Insulin receptor substrate 1.	Growth factor receptor-bound protein 2.	0.995
IRS1	IRS2	A0A2Y9MMM9	A0A2Y9NC55	Insulin receptor substrate 1.	Insulin receptor substrate 2.	0.944
IRS2	GRB2	A0A2Y9NC55	A0A2Y9PJ90	Insulin receptor substrate 2.	Growth factor receptor-bound protein 2.	0.982
IRS2	IRS1	A0A2Y9NC55	A0A2Y9MMM9	Insulin receptor substrate 2.	Insulin receptor substrate 1.	0.944
LOC111181964	GRB2	A0A2Y9PK20	A0A2Y9PJ90	Uncharacterized protein LOC111181964 isoform X1.	Growth factor receptor-bound protein 2.	0.980
SOS1	GRB2	A0A2Y9N647	A0A2Y9PJ90	Son of sevenless homolog 1 isoform X1.	Growth factor receptor-bound protein 2.	0.999