43 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CDC42	Cell division control protein 42 homolog isoform X2. (191 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	PIK3CG	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1102 aa)
	VAV1	Proto-oncogene vav isoform X1. (845 aa)
	PIK3R2	Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
	FCER1G	High affinity immunoglobulin epsilon receptor subunit gamma. (86 aa)
	LYN	Tyrosine-protein kinase. (518 aa)
	COL1A1	Collagen alpha-1(I) chain. (1463 aa)
	LOC111167795	Rho-related GTP-binding protein RhoG-like isoform X1. (230 aa)
	SYK	Tyrosine-protein kinase. (626 aa)
	LOC111170545	Rho-related GTP-binding protein RhoG. (191 aa)
	MFSD6	Major facilitator superfamily domain-containing protein 6 isoform X1. (800 aa)
	MPIG6B	Megakaryocyte and platelet inhibitory receptor G6b isoform X1. (286 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	CLNK	Cytokine-dependent hematopoietic cell linker isoform X1. (452 aa)
	PIK3R3	Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa)
	RHOA	Transforming protein RhoA. (193 aa)
	CLEC1B	C-type lectin domain family 1 member B isoform X1. (226 aa)
	CLEC1A	C-type lectin domain family 1 member A isoform X1. (273 aa)
	RHOB	Rho-related GTP-binding protein RhoB. (196 aa)
	VAV2	Guanine nucleotide exchange factor VAV2 isoform X1. (879 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	CLEC9A	C-type lectin domain family 9 member A isoform X1. (266 aa)
	LCK	Tyrosine-protein kinase. (509 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
	VAV3	Guanine nucleotide exchange factor VAV3. (954 aa)
	GP6	Platelet glycoprotein VI isoform X1. (464 aa)
	COL1A2	Collagen alpha-2(I) chain. (1366 aa)
	RAC1	Ras-related C3 botulinum toxin substrate 1. (192 aa)
	SPNS1	Protein spinster homolog 1 isoform X1. (606 aa)
	LAT	Linker for activation of T-cells family member 1 isoform X1. (270 aa)
	RAC2	Ras-related C3 botulinum toxin substrate 2 isoform X2. (192 aa)
	MFSD6L	Major facilitator superfamily domain-containing protein 6-like. (595 aa)
	PDPK1	3-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
	PDPN	Podoplanin isoform X1. (235 aa)
	LCP2	Lymphocyte cytosolic protein 2 isoform X1. (534 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	PIK3R5	Phosphoinositide 3-kinase regulatory subunit 5 isoform X1. (871 aa)
	PIK3R6	Phosphoinositide 3-kinase regulatory subunit 6 isoform X1. (881 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
	PRDM2	PR domain zinc finger protein 2 isoform X1. (1702 aa)
	LOC111187198	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (617 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	FYN	A0A2Y9LCK9	A0A2Y9LLH3	Cell division control protein 42 homolog isoform X2.	Tyrosine-protein kinase.	0.971
CDC42	LCK	A0A2Y9LCK9	A0A2Y9NNB7	Cell division control protein 42 homolog isoform X2.	Tyrosine-protein kinase.	0.562
CDC42	LCP2	A0A2Y9LCK9	A0A2Y9Q5Y1	Cell division control protein 42 homolog isoform X2.	Lymphocyte cytosolic protein 2 isoform X1.	0.439
CDC42	LOC111167795	A0A2Y9LCK9	A0A2Y9MCE5	Cell division control protein 42 homolog isoform X2.	Rho-related GTP-binding protein RhoG-like isoform X1.	0.453
CDC42	LOC111170545	A0A2Y9LCK9	A0A2Y9MKC6	Cell division control protein 42 homolog isoform X2.	Rho-related GTP-binding protein RhoG.	0.453
CDC42	LYN	A0A2Y9LCK9	A0A2Y9LZZ2	Cell division control protein 42 homolog isoform X2.	Tyrosine-protein kinase.	0.506
CDC42	PDPK1	A0A2Y9LCK9	A0A2Y9Q4F2	Cell division control protein 42 homolog isoform X2.	3-phosphoinositide-dependent protein kinase 1 isoform X1.	0.429
CDC42	PIK3CA	A0A2Y9LCK9	A0A2Y9MZW2	Cell division control protein 42 homolog isoform X2.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.971
CDC42	PIK3CB	A0A2Y9LCK9	A0A2Y9NZC3	Cell division control protein 42 homolog isoform X2.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.994
CDC42	PIK3R1	A0A2Y9LCK9	A0A2Y9Q8T5	Cell division control protein 42 homolog isoform X2.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.962
CDC42	PIK3R2	A0A2Y9LCK9	A0A2Y9LXY5	Cell division control protein 42 homolog isoform X2.	Phosphatidylinositol 3-kinase regulatory subunit beta.	0.953
CDC42	PIK3R3	A0A2Y9LCK9	A0A2Y9NAQ0	Cell division control protein 42 homolog isoform X2.	Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1.	0.947
CDC42	PLCG2	A0A2Y9LCK9	A0A2Y9NXP3	Cell division control protein 42 homolog isoform X2.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.450
CDC42	RAC1	A0A2Y9LCK9	A0A2Y9PL77	Cell division control protein 42 homolog isoform X2.	Ras-related C3 botulinum toxin substrate 1.	0.969
CDC42	RAC2	A0A2Y9LCK9	A0A2Y9PZI8	Cell division control protein 42 homolog isoform X2.	Ras-related C3 botulinum toxin substrate 2 isoform X2.	0.631
CDC42	RHOA	A0A2Y9LCK9	A0A2Y9NBP6	Cell division control protein 42 homolog isoform X2.	Transforming protein RhoA.	0.958
CDC42	RHOB	A0A2Y9LCK9	A0A2Y9NF19	Cell division control protein 42 homolog isoform X2.	Rho-related GTP-binding protein RhoB.	0.567
CDC42	SYK	A0A2Y9LCK9	A0A2Y9MGM5	Cell division control protein 42 homolog isoform X2.	Tyrosine-protein kinase.	0.427
CDC42	VAV1	A0A2Y9LCK9	A0A2Y9LSY4	Cell division control protein 42 homolog isoform X2.	Proto-oncogene vav isoform X1.	0.988
CDC42	VAV2	A0A2Y9LCK9	A0A2Y9NG52	Cell division control protein 42 homolog isoform X2.	Guanine nucleotide exchange factor VAV2 isoform X1.	0.983