17 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111165935	Ras-like protein isoform X1. (285 aa)
	SHC1	SHC-transforming protein 1 isoform X1. (609 aa)
	HRAS	GTPase HRas isoform X1. (189 aa)
	ERAS	GTPase ERas. (233 aa)
	ERBB4	Receptor protein-tyrosine kinase. (1308 aa)
	NRG1	Pro-neuregulin-1, membrane-bound isoform isoform X1. (852 aa)
	SOS1	Son of sevenless homolog 1 isoform X1. (1333 aa)
	KRAS	GTPase KRas. (188 aa)
	NRG4	Pro-neuregulin-4, membrane-bound isoform. (116 aa)
	BTC	Probetacellulin. (178 aa)
	EREG	Proepiregulin. (163 aa)
	NRG3	Pro-neuregulin-3, membrane-bound isoform isoform X2. (725 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	HBEGF	Proheparin-binding EGF-like growth factor. (208 aa)
	NRG2	Pro-neuregulin-2, membrane-bound isoform isoform X1. (845 aa)
	NRAS	GTPase NRas. (189 aa)
	CSDE1	Cold shock domain-containing protein E1 isoform X1. (798 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTC	ERBB4	A0A2Y9QJ26	A0A2Y9MQV3	Probetacellulin.	Receptor protein-tyrosine kinase.	0.985
BTC	EREG	A0A2Y9QJ26	A0A2Y9QC21	Probetacellulin.	Proepiregulin.	0.743
BTC	GRB2	A0A2Y9QJ26	A0A2Y9PJ90	Probetacellulin.	Growth factor receptor-bound protein 2.	0.450
BTC	HBEGF	A0A2Y9QJ26	A0A2Y9PFK7	Probetacellulin.	Proheparin-binding EGF-like growth factor.	0.822
BTC	KRAS	A0A2Y9QJ26	A0A2Y9NF08	Probetacellulin.	GTPase KRas.	0.528
BTC	NRG1	A0A2Y9QJ26	A0A2Y9N632	Probetacellulin.	Pro-neuregulin-1, membrane-bound isoform isoform X1.	0.604
BTC	NRG2	A0A2Y9QJ26	A0A2Y9PCK2	Probetacellulin.	Pro-neuregulin-2, membrane-bound isoform isoform X1.	0.604
BTC	NRG4	A0A2Y9QJ26	A0A2Y9NSD7	Probetacellulin.	Pro-neuregulin-4, membrane-bound isoform.	0.533
CSDE1	ERBB4	A0A2Y9P0H2	A0A2Y9MQV3	Cold shock domain-containing protein E1 isoform X1.	Receptor protein-tyrosine kinase.	0.500
CSDE1	GRB2	A0A2Y9P0H2	A0A2Y9PJ90	Cold shock domain-containing protein E1 isoform X1.	Growth factor receptor-bound protein 2.	0.565
CSDE1	SOS1	A0A2Y9P0H2	A0A2Y9N647	Cold shock domain-containing protein E1 isoform X1.	Son of sevenless homolog 1 isoform X1.	0.607
ERAS	ERBB4	A0A2Y9MKI3	A0A2Y9MQV3	GTPase ERas.	Receptor protein-tyrosine kinase.	0.500
ERAS	GRB2	A0A2Y9MKI3	A0A2Y9PJ90	GTPase ERas.	Growth factor receptor-bound protein 2.	0.565
ERAS	SOS1	A0A2Y9MKI3	A0A2Y9N647	GTPase ERas.	Son of sevenless homolog 1 isoform X1.	0.642
ERBB4	BTC	A0A2Y9MQV3	A0A2Y9QJ26	Receptor protein-tyrosine kinase.	Probetacellulin.	0.985
ERBB4	CSDE1	A0A2Y9MQV3	A0A2Y9P0H2	Receptor protein-tyrosine kinase.	Cold shock domain-containing protein E1 isoform X1.	0.500
ERBB4	ERAS	A0A2Y9MQV3	A0A2Y9MKI3	Receptor protein-tyrosine kinase.	GTPase ERas.	0.500
ERBB4	EREG	A0A2Y9MQV3	A0A2Y9QC21	Receptor protein-tyrosine kinase.	Proepiregulin.	0.992
ERBB4	GRB2	A0A2Y9MQV3	A0A2Y9PJ90	Receptor protein-tyrosine kinase.	Growth factor receptor-bound protein 2.	0.986
ERBB4	HBEGF	A0A2Y9MQV3	A0A2Y9PFK7	Receptor protein-tyrosine kinase.	Proheparin-binding EGF-like growth factor.	0.990