16 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MKNK1	MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1; Belongs to the protein kinase superfamily. (435 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
	RPS27A	ubiquitin-40S ribosomal protein S27a. (156 aa)
	SRC	Tyrosine-protein kinase. (562 aa)
	MKNK2	MAP kinase-interacting serine/threonine-protein kinase 2; Belongs to the protein kinase superfamily. (463 aa)
	MAPK1	Mitogen-activated protein kinase. (380 aa)
	LOC111187198	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (617 aa)
	FNDC3A	Fibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
	FNDC3B	Fibronectin type III domain-containing protein 3B isoform X1. (1215 aa)
	PPP2CB	Serine/threonine-protein phosphatase. (309 aa)
	CBL	E3 ubiquitin-protein ligase CBL isoform X1. (910 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	PPP2CA	Serine/threonine-protein phosphatase. (309 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa)
	BRAF	Serine/threonine-protein kinase B-raf isoform X1. (762 aa)
	SPRY2	Protein sprouty homolog 2. (315 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRAF	GRB2	A0A2Y9NQW5	A0A2Y9PJ90	Serine/threonine-protein kinase B-raf isoform X1.	Growth factor receptor-bound protein 2.	0.446
BRAF	MAPK1	A0A2Y9NQW5	A0A2Y9LEH4	Serine/threonine-protein kinase B-raf isoform X1.	Mitogen-activated protein kinase.	0.827
BRAF	MAPK3	A0A2Y9NQW5	A0A2Y9PDR5	Serine/threonine-protein kinase B-raf isoform X1.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.826
BRAF	PPP2CA	A0A2Y9NQW5	A0A2Y9PGY2	Serine/threonine-protein kinase B-raf isoform X1.	Serine/threonine-protein phosphatase.	0.477
BRAF	PPP2CB	A0A2Y9NQW5	A0A2Y9MWR6	Serine/threonine-protein kinase B-raf isoform X1.	Serine/threonine-protein phosphatase.	0.477
BRAF	PTPN11	A0A2Y9NQW5	A0A2Y9QEG1	Serine/threonine-protein kinase B-raf isoform X1.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.509
BRAF	SPRY2	A0A2Y9NQW5	A0A2Y9NMR6	Serine/threonine-protein kinase B-raf isoform X1.	Protein sprouty homolog 2.	0.937
BRAF	SRC	A0A2Y9NQW5	A0A2Y9PSD7	Serine/threonine-protein kinase B-raf isoform X1.	Tyrosine-protein kinase.	0.540
CBL	GRB2	A0A2Y9M339	A0A2Y9PJ90	E3 ubiquitin-protein ligase CBL isoform X1.	Growth factor receptor-bound protein 2.	0.997
CBL	LOC111187198	A0A2Y9M339	A0A2Y9QG58	E3 ubiquitin-protein ligase CBL isoform X1.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.614
CBL	PTPN11	A0A2Y9M339	A0A2Y9QEG1	E3 ubiquitin-protein ligase CBL isoform X1.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.707
CBL	RPS27A	A0A2Y9M339	A0A2Y9Q1L7	E3 ubiquitin-protein ligase CBL isoform X1.	ubiquitin-40S ribosomal protein S27a.	0.841
CBL	SPRY2	A0A2Y9M339	A0A2Y9NMR6	E3 ubiquitin-protein ligase CBL isoform X1.	Protein sprouty homolog 2.	0.998
CBL	SRC	A0A2Y9M339	A0A2Y9PSD7	E3 ubiquitin-protein ligase CBL isoform X1.	Tyrosine-protein kinase.	0.877
GRB2	BRAF	A0A2Y9PJ90	A0A2Y9NQW5	Growth factor receptor-bound protein 2.	Serine/threonine-protein kinase B-raf isoform X1.	0.446
GRB2	CBL	A0A2Y9PJ90	A0A2Y9M339	Growth factor receptor-bound protein 2.	E3 ubiquitin-protein ligase CBL isoform X1.	0.997
GRB2	LOC111187198	A0A2Y9PJ90	A0A2Y9QG58	Growth factor receptor-bound protein 2.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.991
GRB2	MAPK1	A0A2Y9PJ90	A0A2Y9LEH4	Growth factor receptor-bound protein 2.	Mitogen-activated protein kinase.	0.604
GRB2	MAPK3	A0A2Y9PJ90	A0A2Y9PDR5	Growth factor receptor-bound protein 2.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.458
GRB2	PPP2CA	A0A2Y9PJ90	A0A2Y9PGY2	Growth factor receptor-bound protein 2.	Serine/threonine-protein phosphatase.	0.473