16 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KIT	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
	FNDC3B	Fibronectin type III domain-containing protein 3B isoform X1. (1215 aa)
	SOS1	Son of sevenless homolog 1 isoform X1. (1333 aa)
	FNDC3A	Fibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	LCK	Tyrosine-protein kinase. (509 aa)
	KITLG	Kit ligand isoform X1. (295 aa)
	SRC	Tyrosine-protein kinase. (562 aa)
	SH2B2	SH2B adapter protein 2 isoform X1. (703 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (670 aa)
	SH2B3	SH2B adapter protein 3 isoform X1. (618 aa)
	YES1	Tyrosine-protein kinase. (541 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	LYN	Tyrosine-protein kinase. (518 aa)
	CBL	E3 ubiquitin-protein ligase CBL isoform X1. (910 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBL	FYN	A0A2Y9M339	A0A2Y9LLH3	E3 ubiquitin-protein ligase CBL isoform X1.	Tyrosine-protein kinase.	0.876
CBL	GRB2	A0A2Y9M339	A0A2Y9PJ90	E3 ubiquitin-protein ligase CBL isoform X1.	Growth factor receptor-bound protein 2.	0.997
CBL	KIT	A0A2Y9M339	A0A2Y9MC24	E3 ubiquitin-protein ligase CBL isoform X1.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.713
CBL	KITLG	A0A2Y9M339	A0A2Y9LH90	E3 ubiquitin-protein ligase CBL isoform X1.	Kit ligand isoform X1.	0.508
CBL	LCK	A0A2Y9M339	A0A2Y9NNB7	E3 ubiquitin-protein ligase CBL isoform X1.	Tyrosine-protein kinase.	0.789
CBL	LYN	A0A2Y9M339	A0A2Y9LZZ2	E3 ubiquitin-protein ligase CBL isoform X1.	Tyrosine-protein kinase.	0.915
CBL	PTPN6	A0A2Y9M339	A0A2Y9NJV6	E3 ubiquitin-protein ligase CBL isoform X1.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.457
CBL	SH2B2	A0A2Y9M339	A0A2Y9PKA3	E3 ubiquitin-protein ligase CBL isoform X1.	SH2B adapter protein 2 isoform X1.	0.971
CBL	SH2B3	A0A2Y9M339	A0A2Y9Q391	E3 ubiquitin-protein ligase CBL isoform X1.	SH2B adapter protein 3 isoform X1.	0.640
CBL	SOS1	A0A2Y9M339	A0A2Y9N647	E3 ubiquitin-protein ligase CBL isoform X1.	Son of sevenless homolog 1 isoform X1.	0.566
CBL	SRC	A0A2Y9M339	A0A2Y9PSD7	E3 ubiquitin-protein ligase CBL isoform X1.	Tyrosine-protein kinase.	0.877
CBL	YES1	A0A2Y9M339	A0A2Y9PB67	E3 ubiquitin-protein ligase CBL isoform X1.	Tyrosine-protein kinase.	0.760
FYN	CBL	A0A2Y9LLH3	A0A2Y9M339	Tyrosine-protein kinase.	E3 ubiquitin-protein ligase CBL isoform X1.	0.876
FYN	GRB2	A0A2Y9LLH3	A0A2Y9PJ90	Tyrosine-protein kinase.	Growth factor receptor-bound protein 2.	0.641
FYN	KIT	A0A2Y9LLH3	A0A2Y9MC24	Tyrosine-protein kinase.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.482
FYN	LCK	A0A2Y9LLH3	A0A2Y9NNB7	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.959
FYN	LYN	A0A2Y9LLH3	A0A2Y9LZZ2	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.985
FYN	PTPN6	A0A2Y9LLH3	A0A2Y9NJV6	Tyrosine-protein kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.646
FYN	SH2B2	A0A2Y9LLH3	A0A2Y9PKA3	Tyrosine-protein kinase.	SH2B adapter protein 2 isoform X1.	0.439
FYN	SOS1	A0A2Y9LLH3	A0A2Y9N647	Tyrosine-protein kinase.	Son of sevenless homolog 1 isoform X1.	0.524