STRINGSTRING
PCSK4 PCSK4 ELANE ELANE CAPN7 CAPN7 BSG BSG C1QTNF7 C1QTNF7 MYT1 MYT1 C1QTNF2 C1QTNF2 ADAM28 ADAM28 COL6A1 COL6A1 COL6A2 COL6A2 COL25A1 COL25A1 SCUBE1 SCUBE1 CAPN15 CAPN15 LAMC1 LAMC1 OPTC OPTC PHYKPL PHYKPL SFRP4 SFRP4 CAPN3 CAPN3 COL1A2 COL1A2 CTSB CTSB SPOCK3 SPOCK3 MMP25 MMP25 CAST CAST LAMB3 LAMB3 SPOCK2 SPOCK2 COL12A1 COL12A1 LOC111184995 LOC111184995 CAPN5 CAPN5 LAMC2 LAMC2 MMP24 MMP24 COL19A1 COL19A1 PLA2G12B PLA2G12B LOC111187866 LOC111187866 COL15A1 COL15A1 COL18A1 COL18A1 TMPRSS6 TMPRSS6 MMP23B MMP23B MMP17 MMP17 FBN3 FBN3 MMP14 MMP14 COL4A5 COL4A5 COL5A3 COL5A3 MMP15 MMP15 EPYC EPYC CAPN6 CAPN6 HSPG2 HSPG2 MMP28 MMP28 CMA1 CMA1 NID1 NID1 DCN DCN EMID1 EMID1 MMP11 MMP11 LOC111166812 LOC111166812 COL10A1 COL10A1 COL4A6 COL4A6 ST18 ST18 MMP2 MMP2 CAPNS2 CAPNS2 CTSL CTSL BCAN BCAN MMP1 MMP1 FBN2 FBN2 SPOCK1 SPOCK1 COL26A1 COL26A1 LOC111180508 LOC111180508 COL8A1 COL8A1 ELN ELN CDH1 CDH1 COL11A1 COL11A1 CAPN12 CAPN12 CAPNS1 CAPNS1 CD44 CD44 LOC111179508 LOC111179508 SCUBE3 SCUBE3 JAZF1 JAZF1 SPP1 SPP1 COL11A2 COL11A2 CAPN8 CAPN8 LOC111176737 LOC111176737 ADAM10 ADAM10 CAPN11 CAPN11 LOC111176736 LOC111176736 COL4A1 COL4A1 ANKRD16 ANKRD16 CAPN2 CAPN2 COL5A1 COL5A1 COL7A1 COL7A1 TMPRSS7 TMPRSS7 COL4A2 COL4A2 CAPN14 CAPN14 MMP19 MMP19 A2ML1 A2ML1 COL8A2 COL8A2 CAPN13 CAPN13 COL2A1 COL2A1 ADAM8 ADAM8 CAPN10 CAPN10 ADAMTS5 ADAMTS5 FN1 FN1 LOC111171097 LOC111171097 COL5A2 COL5A2 COL3A1 COL3A1 HTRA1 HTRA1 COL6A3 COL6A3 FRZB FRZB MMP20 MMP20 TIMP1 TIMP1 MMP8 MMP8 COL13A1 COL13A1 CAPN1 CAPN1 FBN1 FBN1 TIMP2 TIMP2 MMP27 MMP27 PLG PLG MMP9 MMP9 COL4A3 COL4A3 MMP16 MMP16 COL6A6 COL6A6 MYT1L MYT1L ADAMTS4 ADAMTS4 MMP7 MMP7 COL1A1 COL1A1 HTRA2 HTRA2 ADGB ADGB LOC111167570 LOC111167570 ADAM15 ADAM15 FURIN FURIN CTSK CTSK CTSS CTSS LOC111168166 LOC111168166 LOC111168189 LOC111168189 LOC111167571 LOC111167571
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (779 aa)
ELANENeutrophil elastase; Belongs to the peptidase S1 family. (308 aa)
CAPN7Calpain-7; Belongs to the peptidase C2 family. (813 aa)
BSGBasigin. (268 aa)
C1QTNF7Complement C1q tumor necrosis factor-related protein 7 isoform X1. (299 aa)
MYT1Myelin transcription factor 1 isoform X1. (1153 aa)
C1QTNF2Complement C1q tumor necrosis factor-related protein 2. (285 aa)
ADAM28Disintegrin and metalloproteinase domain-containing protein 28. (775 aa)
COL6A1Collagen alpha-1(VI) chain. (1027 aa)
COL6A2Collagen alpha-2(VI) chain isoform X1. (1027 aa)
COL25A1Collagen alpha-1(XXV) chain. (628 aa)
SCUBE1Signal peptide, CUB and EGF-like domain-containing protein 1 isoform X1. (1017 aa)
CAPN15Calpain-15 isoform X1; Belongs to the peptidase C2 family. (1138 aa)
LAMC1Laminin subunit gamma-1. (1608 aa)
OPTCOpticin. (332 aa)
PHYKPL5-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (450 aa)
SFRP4Secreted frizzled-related protein 4. (346 aa)
CAPN3Calpain-3 isoform X4; Belongs to the peptidase C2 family. (822 aa)
COL1A2Collagen alpha-2(I) chain. (1366 aa)
CTSBCathepsin B isoform X1; Belongs to the peptidase C1 family. (334 aa)
SPOCK3Testican-3. (428 aa)
MMP25Matrix metalloproteinase-25 isoform X1. (552 aa)
CASTCalpastatin isoform X1. (799 aa)
LAMB3Laminin subunit beta-3. (1172 aa)
SPOCK2Testican-2. (423 aa)
COL12A1Collagen alpha-1(XII) chain isoform X1. (3120 aa)
LOC111184995Tryptase-2-like; Belongs to the peptidase S1 family. (275 aa)
CAPN5Calpain-5; Belongs to the peptidase C2 family. (640 aa)
LAMC2Laminin subunit gamma-2. (1191 aa)
MMP24Matrix metalloproteinase-24 isoform X1. (638 aa)
COL19A1Collagen alpha-1(XIX) chain. (1155 aa)
PLA2G12BGroup XIIB secretory phospholipase A2-like protein isoform X1. (195 aa)
LOC111187866LOW QUALITY PROTEIN: protein HP-25 homolog 1-like. (213 aa)
COL15A1Collagen alpha-1(XV) chain. (1312 aa)
COL18A1Collagen alpha-1(XVIII) chain isoform X1. (1785 aa)
TMPRSS6Transmembrane protease serine 6 isoform X1; Belongs to the peptidase S1 family. (800 aa)
MMP23BMatrix metalloproteinase-23. (393 aa)
MMP17Matrix metalloproteinase-17 isoform X1. (637 aa)
FBN3Fibrillin-3 isoform X1. (2823 aa)
MMP14Matrix metalloproteinase-14. (582 aa)
COL4A5Collagen alpha-5(IV) chain. (1685 aa)
COL5A3Collagen alpha-3(V) chain isoform X1. (1746 aa)
MMP15Matrix metalloproteinase-15 isoform X1. (691 aa)
EPYCEpiphycan. (321 aa)
CAPN6Calpain-6; Belongs to the peptidase C2 family. (641 aa)
HSPG2Basement membrane-specific heparan sulfate proteoglycan core protein isoform X1. (4408 aa)
MMP28Matrix metalloproteinase-28 isoform X1. (520 aa)
CMA1LOW QUALITY PROTEIN: chymase; Belongs to the peptidase S1 family. (247 aa)
NID1Nidogen-1 isoform X1. (1242 aa)
DCNDecorin; May affect the rate of fibrils formation. (360 aa)
EMID1EMI domain-containing protein 1 isoform X1. (460 aa)
MMP11Stromelysin-3. (489 aa)
LOC111166812Cathepsin L1; Belongs to the peptidase C1 family. (334 aa)
COL10A1Collagen alpha-1(X) chain. (705 aa)
COL4A6Collagen alpha-6(IV) chain. (1706 aa)
ST18Suppression of tumorigenicity 18 protein isoform X1. (1053 aa)
MMP272 kDa type IV collagenase. (661 aa)
CAPNS2Calpain small subunit 2. (156 aa)
CTSLCathepsin L1; Belongs to the peptidase C1 family. (333 aa)
BCANBrevican core protein isoform X1. (909 aa)
MMP1Interstitial collagenase isoform X1. (554 aa)
FBN2Fibrillin-2. (2912 aa)
SPOCK1Testican-1 isoform X1. (442 aa)
COL26A1Collagen alpha-1(XXVI) chain. (438 aa)
LOC111180508Kallikrein-7-like; Belongs to the peptidase S1 family. (254 aa)
COL8A1Collagen alpha-1(VIII) chain isoform X1. (745 aa)
ELNElastin isoform X1. (748 aa)
CDH1Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (885 aa)
COL11A1Collagen alpha-1(XI) chain isoform X1. (1805 aa)
CAPN12LOW QUALITY PROTEIN: calpain-12; Belongs to the peptidase C2 family. (773 aa)
CAPNS1Calpain small subunit 1. (263 aa)
CD44CD44 antigen isoform X1. (742 aa)
LOC111179508Serine protease 56-like isoform X1. (349 aa)
SCUBE3Signal peptide, CUB and EGF-like domain-containing protein 3. (864 aa)
JAZF1Juxtaposed with another zinc finger protein 1 isoform X1. (243 aa)
SPP1Osteopontin. (362 aa)
COL11A2LOW QUALITY PROTEIN: collagen alpha-2(XI) chain. (1736 aa)
CAPN8LOW QUALITY PROTEIN: calpain-8; Belongs to the peptidase C2 family. (697 aa)
LOC111176737Alpha-2-macroglobulin isoform X1. (1479 aa)
ADAM10Disintegrin and metalloproteinase domain-containing protein 10. (748 aa)
CAPN11Calpain-11; Belongs to the peptidase C2 family. (700 aa)
LOC111176736Pregnancy zone protein-like. (1486 aa)
COL4A1Collagen alpha-1(IV) chain isoform X1. (1668 aa)
ANKRD16Ankyrin repeat domain-containing protein 16 isoform X1. (442 aa)
CAPN2Calpain-2 catalytic subunit isoform X1; Belongs to the peptidase C2 family. (703 aa)
COL5A1Collagen alpha-1(V) chain isoform X3. (1844 aa)
COL7A1Collagen alpha-1(VII) chain. (2942 aa)
TMPRSS7Transmembrane protease serine 7 isoform X1; Belongs to the peptidase S1 family. (717 aa)
COL4A2Collagen alpha-2(IV) chain isoform X1. (1760 aa)
CAPN14LOW QUALITY PROTEIN: calpain-14; Belongs to the peptidase C2 family. (441 aa)
MMP19Matrix metalloproteinase-19. (540 aa)
A2ML1Alpha-2-macroglobulin-like protein 1. (1445 aa)
COL8A2Collagen alpha-2(VIII) chain. (705 aa)
CAPN13LOW QUALITY PROTEIN: calpain-13; Belongs to the peptidase C2 family. (687 aa)
COL2A1Collagen alpha-1(II) chain. (1487 aa)
ADAM8Disintegrin and metalloproteinase domain-containing protein 8 isoform X1. (838 aa)
CAPN10Calpain-10 isoform X1; Belongs to the peptidase C2 family. (704 aa)
ADAMTS5A disintegrin and metalloproteinase with thrombospondin motifs 5. (931 aa)
FN1Fibronectin isoform X5. (2478 aa)
LOC111171097Cathepsin G-like isoform X1; Belongs to the peptidase S1 family. (307 aa)
COL5A2Collagen alpha-2(V) chain isoform X1. (1499 aa)
COL3A1Collagen alpha-1(III) chain. (1464 aa)
HTRA1Serine protease HTRA1. (509 aa)
COL6A3Collagen alpha-3(VI) chain isoform X1. (3229 aa)
FRZBSecreted frizzled-related protein 3. (325 aa)
MMP20Matrix metalloproteinase-20. (483 aa)
TIMP1Metalloproteinase inhibitor 1. (257 aa)
MMP8Neutrophil collagenase isoform X1. (468 aa)
COL13A1Collagen alpha-1(XIII) chain isoform X1. (754 aa)
CAPN1Calpain-1 catalytic subunit; Belongs to the peptidase C2 family. (716 aa)
FBN1Fibrillin-1 isoform X1. (2871 aa)
TIMP2Metalloproteinase inhibitor 2. (220 aa)
MMP27Matrix metalloproteinase-27 isoform X1. (511 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (812 aa)
MMP9Matrix metalloproteinase-9. (709 aa)
COL4A3Collagen alpha-3(IV) chain. (1670 aa)
MMP16Matrix metalloproteinase-16. (548 aa)
COL6A6Collagen alpha-6(VI) chain isoform X1. (2268 aa)
MYT1LMyelin transcription factor 1-like protein isoform X1. (1215 aa)
ADAMTS4A disintegrin and metalloproteinase with thrombospondin motifs 4. (834 aa)
MMP7Matrilysin isoform X2. (270 aa)
COL1A1Collagen alpha-1(I) chain. (1463 aa)
HTRA2Serine protease HTRA2, mitochondrial. (458 aa)
ADGBAndroglobin; Belongs to the peptidase C2 family. (1633 aa)
LOC111167570Stromelysin-1-like. (479 aa)
ADAM15Disintegrin and metalloproteinase domain-containing protein 15 isoform X1. (866 aa)
FURINFurin; Belongs to the peptidase S8 family. (792 aa)
CTSKCathepsin K isoform X1; Belongs to the peptidase C1 family. (358 aa)
CTSSCathepsin S; Belongs to the peptidase C1 family. (340 aa)
LOC111168166Collagen alpha-5(VI) chain-like isoform X1. (865 aa)
LOC111168189Collagen alpha-5(VI) chain-like. (1419 aa)
LOC111167571Collagenase 3. (471 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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