132 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PCSK4	Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (779 aa)
	ELANE	Neutrophil elastase; Belongs to the peptidase S1 family. (308 aa)
	CAPN7	Calpain-7; Belongs to the peptidase C2 family. (813 aa)
	BSG	Basigin. (268 aa)
	C1QTNF7	Complement C1q tumor necrosis factor-related protein 7 isoform X1. (299 aa)
	MYT1	Myelin transcription factor 1 isoform X1. (1153 aa)
	C1QTNF2	Complement C1q tumor necrosis factor-related protein 2. (285 aa)
	ADAM28	Disintegrin and metalloproteinase domain-containing protein 28. (775 aa)
	COL6A1	Collagen alpha-1(VI) chain. (1027 aa)
	COL6A2	Collagen alpha-2(VI) chain isoform X1. (1027 aa)
	COL25A1	Collagen alpha-1(XXV) chain. (628 aa)
	SCUBE1	Signal peptide, CUB and EGF-like domain-containing protein 1 isoform X1. (1017 aa)
	CAPN15	Calpain-15 isoform X1; Belongs to the peptidase C2 family. (1138 aa)
	LAMC1	Laminin subunit gamma-1. (1608 aa)
	OPTC	Opticin. (332 aa)
	PHYKPL	5-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (450 aa)
	SFRP4	Secreted frizzled-related protein 4. (346 aa)
	CAPN3	Calpain-3 isoform X4; Belongs to the peptidase C2 family. (822 aa)
	COL1A2	Collagen alpha-2(I) chain. (1366 aa)
	CTSB	Cathepsin B isoform X1; Belongs to the peptidase C1 family. (334 aa)
	SPOCK3	Testican-3. (428 aa)
	MMP25	Matrix metalloproteinase-25 isoform X1. (552 aa)
	CAST	Calpastatin isoform X1. (799 aa)
	LAMB3	Laminin subunit beta-3. (1172 aa)
	SPOCK2	Testican-2. (423 aa)
	COL12A1	Collagen alpha-1(XII) chain isoform X1. (3120 aa)
	LOC111184995	Tryptase-2-like; Belongs to the peptidase S1 family. (275 aa)
	CAPN5	Calpain-5; Belongs to the peptidase C2 family. (640 aa)
	LAMC2	Laminin subunit gamma-2. (1191 aa)
	MMP24	Matrix metalloproteinase-24 isoform X1. (638 aa)
	COL19A1	Collagen alpha-1(XIX) chain. (1155 aa)
	PLA2G12B	Group XIIB secretory phospholipase A2-like protein isoform X1. (195 aa)
	LOC111187866	LOW QUALITY PROTEIN: protein HP-25 homolog 1-like. (213 aa)
	COL15A1	Collagen alpha-1(XV) chain. (1312 aa)
	COL18A1	Collagen alpha-1(XVIII) chain isoform X1. (1785 aa)
	TMPRSS6	Transmembrane protease serine 6 isoform X1; Belongs to the peptidase S1 family. (800 aa)
	MMP23B	Matrix metalloproteinase-23. (393 aa)
	MMP17	Matrix metalloproteinase-17 isoform X1. (637 aa)
	FBN3	Fibrillin-3 isoform X1. (2823 aa)
	MMP14	Matrix metalloproteinase-14. (582 aa)
	COL4A5	Collagen alpha-5(IV) chain. (1685 aa)
	COL5A3	Collagen alpha-3(V) chain isoform X1. (1746 aa)
	MMP15	Matrix metalloproteinase-15 isoform X1. (691 aa)
	EPYC	Epiphycan. (321 aa)
	CAPN6	Calpain-6; Belongs to the peptidase C2 family. (641 aa)
	HSPG2	Basement membrane-specific heparan sulfate proteoglycan core protein isoform X1. (4408 aa)
	MMP28	Matrix metalloproteinase-28 isoform X1. (520 aa)
	CMA1	LOW QUALITY PROTEIN: chymase; Belongs to the peptidase S1 family. (247 aa)
	NID1	Nidogen-1 isoform X1. (1242 aa)
	DCN	Decorin; May affect the rate of fibrils formation. (360 aa)
	EMID1	EMI domain-containing protein 1 isoform X1. (460 aa)
	MMP11	Stromelysin-3. (489 aa)
	LOC111166812	Cathepsin L1; Belongs to the peptidase C1 family. (334 aa)
	COL10A1	Collagen alpha-1(X) chain. (705 aa)
	COL4A6	Collagen alpha-6(IV) chain. (1706 aa)
	ST18	Suppression of tumorigenicity 18 protein isoform X1. (1053 aa)
	MMP2	72 kDa type IV collagenase. (661 aa)
	CAPNS2	Calpain small subunit 2. (156 aa)
	CTSL	Cathepsin L1; Belongs to the peptidase C1 family. (333 aa)
	BCAN	Brevican core protein isoform X1. (909 aa)
	MMP1	Interstitial collagenase isoform X1. (554 aa)
	FBN2	Fibrillin-2. (2912 aa)
	SPOCK1	Testican-1 isoform X1. (442 aa)
	COL26A1	Collagen alpha-1(XXVI) chain. (438 aa)
	LOC111180508	Kallikrein-7-like; Belongs to the peptidase S1 family. (254 aa)
	COL8A1	Collagen alpha-1(VIII) chain isoform X1. (745 aa)
	ELN	Elastin isoform X1. (748 aa)
	CDH1	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (885 aa)
	COL11A1	Collagen alpha-1(XI) chain isoform X1. (1805 aa)
	CAPN12	LOW QUALITY PROTEIN: calpain-12; Belongs to the peptidase C2 family. (773 aa)
	CAPNS1	Calpain small subunit 1. (263 aa)
	CD44	CD44 antigen isoform X1. (742 aa)
	LOC111179508	Serine protease 56-like isoform X1. (349 aa)
	SCUBE3	Signal peptide, CUB and EGF-like domain-containing protein 3. (864 aa)
	JAZF1	Juxtaposed with another zinc finger protein 1 isoform X1. (243 aa)
	SPP1	Osteopontin. (362 aa)
	COL11A2	LOW QUALITY PROTEIN: collagen alpha-2(XI) chain. (1736 aa)
	CAPN8	LOW QUALITY PROTEIN: calpain-8; Belongs to the peptidase C2 family. (697 aa)
	LOC111176737	Alpha-2-macroglobulin isoform X1. (1479 aa)
	ADAM10	Disintegrin and metalloproteinase domain-containing protein 10. (748 aa)
	CAPN11	Calpain-11; Belongs to the peptidase C2 family. (700 aa)
	LOC111176736	Pregnancy zone protein-like. (1486 aa)
	COL4A1	Collagen alpha-1(IV) chain isoform X1. (1668 aa)
	ANKRD16	Ankyrin repeat domain-containing protein 16 isoform X1. (442 aa)
	CAPN2	Calpain-2 catalytic subunit isoform X1; Belongs to the peptidase C2 family. (703 aa)
	COL5A1	Collagen alpha-1(V) chain isoform X3. (1844 aa)
	COL7A1	Collagen alpha-1(VII) chain. (2942 aa)
	TMPRSS7	Transmembrane protease serine 7 isoform X1; Belongs to the peptidase S1 family. (717 aa)
	COL4A2	Collagen alpha-2(IV) chain isoform X1. (1760 aa)
	CAPN14	LOW QUALITY PROTEIN: calpain-14; Belongs to the peptidase C2 family. (441 aa)
	MMP19	Matrix metalloproteinase-19. (540 aa)
	A2ML1	Alpha-2-macroglobulin-like protein 1. (1445 aa)
	COL8A2	Collagen alpha-2(VIII) chain. (705 aa)
	CAPN13	LOW QUALITY PROTEIN: calpain-13; Belongs to the peptidase C2 family. (687 aa)
	COL2A1	Collagen alpha-1(II) chain. (1487 aa)
	ADAM8	Disintegrin and metalloproteinase domain-containing protein 8 isoform X1. (838 aa)
	CAPN10	Calpain-10 isoform X1; Belongs to the peptidase C2 family. (704 aa)
	ADAMTS5	A disintegrin and metalloproteinase with thrombospondin motifs 5. (931 aa)
	FN1	Fibronectin isoform X5. (2478 aa)
	LOC111171097	Cathepsin G-like isoform X1; Belongs to the peptidase S1 family. (307 aa)
	COL5A2	Collagen alpha-2(V) chain isoform X1. (1499 aa)
	COL3A1	Collagen alpha-1(III) chain. (1464 aa)
	HTRA1	Serine protease HTRA1. (509 aa)
	COL6A3	Collagen alpha-3(VI) chain isoform X1. (3229 aa)
	FRZB	Secreted frizzled-related protein 3. (325 aa)
	MMP20	Matrix metalloproteinase-20. (483 aa)
	TIMP1	Metalloproteinase inhibitor 1. (257 aa)
	MMP8	Neutrophil collagenase isoform X1. (468 aa)
	COL13A1	Collagen alpha-1(XIII) chain isoform X1. (754 aa)
	CAPN1	Calpain-1 catalytic subunit; Belongs to the peptidase C2 family. (716 aa)
	FBN1	Fibrillin-1 isoform X1. (2871 aa)
	TIMP2	Metalloproteinase inhibitor 2. (220 aa)
	MMP27	Matrix metalloproteinase-27 isoform X1. (511 aa)
	PLG	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (812 aa)
	MMP9	Matrix metalloproteinase-9. (709 aa)
	COL4A3	Collagen alpha-3(IV) chain. (1670 aa)
	MMP16	Matrix metalloproteinase-16. (548 aa)
	COL6A6	Collagen alpha-6(VI) chain isoform X1. (2268 aa)
	MYT1L	Myelin transcription factor 1-like protein isoform X1. (1215 aa)
	ADAMTS4	A disintegrin and metalloproteinase with thrombospondin motifs 4. (834 aa)
	MMP7	Matrilysin isoform X2. (270 aa)
	COL1A1	Collagen alpha-1(I) chain. (1463 aa)
	HTRA2	Serine protease HTRA2, mitochondrial. (458 aa)
	ADGB	Androglobin; Belongs to the peptidase C2 family. (1633 aa)
	LOC111167570	Stromelysin-1-like. (479 aa)
	ADAM15	Disintegrin and metalloproteinase domain-containing protein 15 isoform X1. (866 aa)
	FURIN	Furin; Belongs to the peptidase S8 family. (792 aa)
	CTSK	Cathepsin K isoform X1; Belongs to the peptidase C1 family. (358 aa)
	CTSS	Cathepsin S; Belongs to the peptidase C1 family. (340 aa)
	LOC111168166	Collagen alpha-5(VI) chain-like isoform X1. (865 aa)
	LOC111168189	Collagen alpha-5(VI) chain-like. (1419 aa)
	LOC111167571	Collagenase 3. (471 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A2ML1	LOC111179508	A0A2Y9NCY1	A0A2Y9P6B6	Alpha-2-macroglobulin-like protein 1.	Serine protease 56-like isoform X1.	0.401
A2ML1	LOC111180508	A0A2Y9NCY1	A0A2Y9PBC4	Alpha-2-macroglobulin-like protein 1.	Kallikrein-7-like; Belongs to the peptidase S1 family.	0.412
A2ML1	PLG	A0A2Y9NCY1	A0A2Y9M5R2	Alpha-2-macroglobulin-like protein 1.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.412
ADAM10	CDH1	A0A2Y9NR06	A0A2Y9P9K7	Disintegrin and metalloproteinase domain-containing protein 10.	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.	0.879
ADAM10	FURIN	A0A2Y9NR06	A0A2Y9MD65	Disintegrin and metalloproteinase domain-containing protein 10.	Furin; Belongs to the peptidase S8 family.	0.538
ADAM10	MMP14	A0A2Y9NR06	A0A2Y9LVK1	Disintegrin and metalloproteinase domain-containing protein 10.	Matrix metalloproteinase-14.	0.495
ADAM10	MMP16	A0A2Y9NR06	A0A2Y9MMD7	Disintegrin and metalloproteinase domain-containing protein 10.	Matrix metalloproteinase-16.	0.437
ADAM10	MMP7	A0A2Y9NR06	A0A2Y9M7S1	Disintegrin and metalloproteinase domain-containing protein 10.	Matrilysin isoform X2.	0.436
ADAM10	MMP9	A0A2Y9NR06	A0A2Y9MNP1	Disintegrin and metalloproteinase domain-containing protein 10.	Matrix metalloproteinase-9.	0.495
ADAM10	PCSK4	A0A2Y9NR06	A0A2Y9MGG2	Disintegrin and metalloproteinase domain-containing protein 10.	Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family.	0.538
ADAM10	TIMP1	A0A2Y9NR06	A0A2Y9M402	Disintegrin and metalloproteinase domain-containing protein 10.	Metalloproteinase inhibitor 1.	0.542
ADAM10	TIMP2	A0A2Y9NR06	A0A2Y9PIP9	Disintegrin and metalloproteinase domain-containing protein 10.	Metalloproteinase inhibitor 2.	0.500
ADAM15	CDH1	A0A2Y9MCU7	A0A2Y9P9K7	Disintegrin and metalloproteinase domain-containing protein 15 isoform X1.	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.	0.818
ADAM15	MMP7	A0A2Y9MCU7	A0A2Y9M7S1	Disintegrin and metalloproteinase domain-containing protein 15 isoform X1.	Matrilysin isoform X2.	0.437
ADAM8	C1QTNF2	A0A2Y9N4A6	A0A2Y9Q643	Disintegrin and metalloproteinase domain-containing protein 8 isoform X1.	Complement C1q tumor necrosis factor-related protein 2.	0.405
ADAM8	MMP2	A0A2Y9N4A6	A0A2Y9M058	Disintegrin and metalloproteinase domain-containing protein 8 isoform X1.	72 kDa type IV collagenase.	0.450
ADAM8	MMP20	A0A2Y9N4A6	A0A2Y9M3F8	Disintegrin and metalloproteinase domain-containing protein 8 isoform X1.	Matrix metalloproteinase-20.	0.450
ADAMTS4	BCAN	A0A2Y9M7E9	A0A2Y9M2G2	A disintegrin and metalloproteinase with thrombospondin motifs 4.	Brevican core protein isoform X1.	0.914
ADAMTS4	COL10A1	A0A2Y9M7E9	A0A2Y9LZ87	A disintegrin and metalloproteinase with thrombospondin motifs 4.	Collagen alpha-1(X) chain.	0.540
ADAMTS4	COL2A1	A0A2Y9M7E9	A0A2Y9N4L6	A disintegrin and metalloproteinase with thrombospondin motifs 4.	Collagen alpha-1(II) chain.	0.642