STRINGSTRING
PCSK4 PCSK4 LOXL3 LOXL3 MFAP4 MFAP4 BMP2 BMP2 FBN3 FBN3 EMILIN2 EMILIN2 MFAP2 MFAP2 BMP7 BMP7 FBLN1 FBLN1 VTN VTN EFEMP1 EFEMP1 MFAP3L MFAP3L GDF5 GDF5 LOXL2 LOXL2 EMILIN3 EMILIN3 EFEMP2 EFEMP2 MFAP3 MFAP3 LTBP3 LTBP3 LOX LOX ITGB8 ITGB8 FIBP FIBP FBN1 FBN1 FBN2 FBN2 ITGB3 ITGB3 ELN ELN LTBP4 LTBP4 BMP6 BMP6 TGFB1 TGFB1 GDF6 GDF6 ITGB1 ITGB1 LOXL1 LOXL1 MFAP5 MFAP5 BMP5 BMP5 TGFB3 TGFB3 ITGA8 ITGA8 TGFB2 TGFB2 EMILIN1 EMILIN1 FBLN5 FBLN5 LTBP1 LTBP1 LOXL4 LOXL4 GDF7 GDF7 ITGB6 ITGB6 FN1 FN1 BMP4 BMP4 ITGAV ITGAV ITGB5 ITGB5 BMP10 BMP10 FBLN2 FBLN2 FURIN FURIN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (779 aa)
LOXL3Lysyl oxidase homolog 3 isoform X1. (772 aa)
MFAP4Microfibril-associated glycoprotein 4 isoform X2. (255 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
FBN3Fibrillin-3 isoform X1. (2823 aa)
EMILIN2EMILIN-2. (1070 aa)
MFAP2Microfibrillar-associated protein 2 isoform X1. (183 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (705 aa)
VTNVitronectin. (565 aa)
EFEMP1EGF-containing fibulin-like extracellular matrix protein 1 isoform X1. (498 aa)
MFAP3LMicrofibrillar-associated protein 3-like. (406 aa)
GDF5Growth/differentiation factor 5. (499 aa)
LOXL2Lysyl oxidase homolog 2. (774 aa)
EMILIN3EMILIN-3. (766 aa)
EFEMP2EGF-containing fibulin-like extracellular matrix protein 2 isoform X1. (523 aa)
MFAP3Microfibril-associated glycoprotein 3. (362 aa)
LTBP3Latent-transforming growth factor beta-binding protein 3 isoform X1. (1557 aa)
LOXProtein-lysine 6-oxidase isoform X1. (425 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (767 aa)
FIBPAcidic fibroblast growth factor intracellular-binding protein isoform X1. (364 aa)
FBN1Fibrillin-1 isoform X1. (2871 aa)
FBN2Fibrillin-2. (2912 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (789 aa)
ELNElastin isoform X1. (748 aa)
LTBP4Latent-transforming growth factor beta-binding protein 4 isoform X1. (1628 aa)
BMP6Bone morphogenetic protein 6. (496 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
GDF6Growth/differentiation factor 6. (461 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
LOXL1Lysyl oxidase homolog 1 isoform X1. (591 aa)
MFAP5Microfibrillar-associated protein 5 isoform X1. (169 aa)
BMP5Bone morphogenetic protein 5 isoform X1. (454 aa)
TGFB3Transforming growth factor beta-3. (456 aa)
ITGA8Integrin alpha-8 isoform X1; Belongs to the integrin alpha chain family. (1062 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
EMILIN1EMILIN-1. (1015 aa)
FBLN5Fibulin-5 isoform X1. (461 aa)
LTBP1Latent-transforming growth factor beta-binding protein 1 isoform X1. (1711 aa)
LOXL4Lysyl oxidase homolog 4 isoform X1. (765 aa)
GDF7Growth/differentiation factor 7. (449 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (808 aa)
FN1Fibronectin isoform X5. (2478 aa)
BMP4Bone morphogenetic protein 4 isoform X2. (408 aa)
ITGAVIntegrin alpha-V isoform X2; Belongs to the integrin alpha chain family. (1048 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (800 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
FBLN2Fibulin-2 isoform X1. (1217 aa)
FURINFurin; Belongs to the peptidase S8 family. (792 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (32%) [HD]