9 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	PROS1	Vitamin K-dependent protein S. (675 aa)
	F10	Coagulation factor X isoform X1. (480 aa)
	GGCX	Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. (758 aa)
	F2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
	PROC	Vitamin K-dependent protein C. (480 aa)
	F7	Coagulation factor VII isoform X1. (447 aa)
	PROZ	Vitamin K-dependent protein Z; Belongs to the peptidase S1 family. (709 aa)
	F9	Coagulation factor IX. (462 aa)
	BGLAP	Osteocalcin; Binds strongly to apatite and calcium. (148 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BGLAP	GGCX	A0A2Y9MD64	Q9MYY3	Osteocalcin; Binds strongly to apatite and calcium.	Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.	0.718
F10	F2	A0A2Y9NBY5	A0A2Y9PXE8	Coagulation factor X isoform X1.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.974
F10	F7	A0A2Y9NBY5	A0A2Y9NSN2	Coagulation factor X isoform X1.	Coagulation factor VII isoform X1.	0.983
F10	F9	A0A2Y9NBY5	A0A2Y9LSD8	Coagulation factor X isoform X1.	Coagulation factor IX.	0.958
F10	GGCX	A0A2Y9NBY5	Q9MYY3	Coagulation factor X isoform X1.	Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.	0.828
F10	PROC	A0A2Y9NBY5	A0A2Y9PTI6	Coagulation factor X isoform X1.	Vitamin K-dependent protein C.	0.631
F2	F10	A0A2Y9PXE8	A0A2Y9NBY5	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor X isoform X1.	0.974
F2	F7	A0A2Y9PXE8	A0A2Y9NSN2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor VII isoform X1.	0.754
F2	F9	A0A2Y9PXE8	A0A2Y9LSD8	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor IX.	0.767
F2	GGCX	A0A2Y9PXE8	Q9MYY3	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.	0.882
F2	PROC	A0A2Y9PXE8	A0A2Y9PTI6	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Vitamin K-dependent protein C.	0.950
F2	PROZ	A0A2Y9PXE8	A0A2Y9NSN7	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Vitamin K-dependent protein Z; Belongs to the peptidase S1 family.	0.681
F7	F10	A0A2Y9NSN2	A0A2Y9NBY5	Coagulation factor VII isoform X1.	Coagulation factor X isoform X1.	0.983
F7	F2	A0A2Y9NSN2	A0A2Y9PXE8	Coagulation factor VII isoform X1.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.754
F7	F9	A0A2Y9NSN2	A0A2Y9LSD8	Coagulation factor VII isoform X1.	Coagulation factor IX.	0.741
F7	GGCX	A0A2Y9NSN2	Q9MYY3	Coagulation factor VII isoform X1.	Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.	0.824
F7	PROC	A0A2Y9NSN2	A0A2Y9PTI6	Coagulation factor VII isoform X1.	Vitamin K-dependent protein C.	0.523
F9	F10	A0A2Y9LSD8	A0A2Y9NBY5	Coagulation factor IX.	Coagulation factor X isoform X1.	0.958
F9	F2	A0A2Y9LSD8	A0A2Y9PXE8	Coagulation factor IX.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.767
F9	F7	A0A2Y9LSD8	A0A2Y9NSN2	Coagulation factor IX.	Coagulation factor VII isoform X1.	0.741