12 items (Delphinapterus leucas) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	F9	Coagulation factor IX. (462 aa)
	BGLAP	Osteocalcin; Binds strongly to apatite and calcium. (148 aa)
	FURIN	Furin; Belongs to the peptidase S8 family. (792 aa)
	PCSK4	Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (779 aa)
	F10	Coagulation factor X isoform X1. (480 aa)
	GAS6	Growth arrest-specific protein 6. (671 aa)
	F7	Coagulation factor VII isoform X1. (447 aa)
	PROZ	Vitamin K-dependent protein Z; Belongs to the peptidase S1 family. (709 aa)
	PROS1	Vitamin K-dependent protein S. (675 aa)
	PROC	Vitamin K-dependent protein C. (480 aa)
	F2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
	GGCX	Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. (758 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BGLAP	FURIN	A0A2Y9MD64	A0A2Y9MD65	Osteocalcin; Binds strongly to apatite and calcium.	Furin; Belongs to the peptidase S8 family.	0.591
BGLAP	GGCX	A0A2Y9MD64	Q9MYY3	Osteocalcin; Binds strongly to apatite and calcium.	Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.	0.718
BGLAP	PCSK4	A0A2Y9MD64	A0A2Y9MGG2	Osteocalcin; Binds strongly to apatite and calcium.	Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family.	0.544
F10	F2	A0A2Y9NBY5	A0A2Y9PXE8	Coagulation factor X isoform X1.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.974
F10	F7	A0A2Y9NBY5	A0A2Y9NSN2	Coagulation factor X isoform X1.	Coagulation factor VII isoform X1.	0.983
F10	F9	A0A2Y9NBY5	A0A2Y9LSD8	Coagulation factor X isoform X1.	Coagulation factor IX.	0.958
F10	FURIN	A0A2Y9NBY5	A0A2Y9MD65	Coagulation factor X isoform X1.	Furin; Belongs to the peptidase S8 family.	0.743
F10	GGCX	A0A2Y9NBY5	Q9MYY3	Coagulation factor X isoform X1.	Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.	0.828
F10	PCSK4	A0A2Y9NBY5	A0A2Y9MGG2	Coagulation factor X isoform X1.	Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family.	0.738
F10	PROC	A0A2Y9NBY5	A0A2Y9PTI6	Coagulation factor X isoform X1.	Vitamin K-dependent protein C.	0.631
F2	F10	A0A2Y9PXE8	A0A2Y9NBY5	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor X isoform X1.	0.974
F2	F7	A0A2Y9PXE8	A0A2Y9NSN2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor VII isoform X1.	0.754
F2	F9	A0A2Y9PXE8	A0A2Y9LSD8	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor IX.	0.767
F2	FURIN	A0A2Y9PXE8	A0A2Y9MD65	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Furin; Belongs to the peptidase S8 family.	0.749
F2	GGCX	A0A2Y9PXE8	Q9MYY3	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.	0.882
F2	PCSK4	A0A2Y9PXE8	A0A2Y9MGG2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family.	0.744
F2	PROC	A0A2Y9PXE8	A0A2Y9PTI6	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Vitamin K-dependent protein C.	0.950
F2	PROZ	A0A2Y9PXE8	A0A2Y9NSN7	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Vitamin K-dependent protein Z; Belongs to the peptidase S1 family.	0.681
F7	F10	A0A2Y9NSN2	A0A2Y9NBY5	Coagulation factor VII isoform X1.	Coagulation factor X isoform X1.	0.983
F7	F2	A0A2Y9NSN2	A0A2Y9PXE8	Coagulation factor VII isoform X1.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.754