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C4BPB C4BPB F2 F2 CD55 CD55 LOC111184737 LOC111184737 GZMK GZMK CLU CLU VTN VTN C6 C6 C7 C7 C9 C9 MASP2 MASP2 C4BPA C4BPA CR1 CR1 LOC111184601 LOC111184601 SERPING1 SERPING1 CR2 CR2 LOC111184729 LOC111184729 CD81 CD81 CD19 CD19 CD59 CD59 IRGQ IRGQ C5AR2 C5AR2 C5AR1 C5AR1 LOC111177076 LOC111177076 C8G C8G FIBCD1 FIBCD1 C3AR1 C3AR1 C5 C5 LOC111177446 LOC111177446 C1R C1R LOC111177077 LOC111177077 CFH CFH C8A C8A SVEP1 SVEP1 C1RL C1RL C1S C1S CPN1 CPN1 MASP1 MASP1 MBL2 MBL2 CSMD1 CSMD1 C2 C2 CPN2 CPN2 GZMM GZMM CFB CFB CFI CFI LOC111170700 LOC111170700 ELANE ELANE CFD CFD LOC111168646 LOC111168646 IGSF9 IGSF9 COLEC11 COLEC11 LOC111166693 LOC111166693 C3 C3 CFP CFP IGSF9B IGSF9B LOC111166100 LOC111166100 C1QB C1QB LOC111163081 LOC111163081 CSMD3 CSMD3 COLEC10 COLEC10 C1QC C1QC C1QA C1QA FCN3 FCN3 IGLL1 IGLL1 CPB2 CPB2 CSMD2 CSMD2 C8B C8B LOC111184602 LOC111184602 LOC111184736 LOC111184736
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
C4BPBC4b-binding protein beta chain isoform X1. (255 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
CD55Complement decay-accelerating factor isoform X1. (590 aa)
LOC111184737Zona pellucida sperm-binding protein 3 receptor-like. (89 aa)
GZMKGranzyme K; Belongs to the peptidase S1 family. (264 aa)
CLUClusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (441 aa)
VTNVitronectin. (565 aa)
C6Complement component C6 isoform X1. (934 aa)
C7Complement component C7. (843 aa)
C9Complement component C9. (548 aa)
MASP2Mannan-binding lectin serine protease 2 isoform X1; Belongs to the peptidase S1 family. (686 aa)
C4BPAC4b-binding protein alpha chain isoform X1. (616 aa)
CR1Complement receptor type 1 isoform X1. (1062 aa)
LOC111184601Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. (336 aa)
SERPING1Plasma protease C1 inhibitor; Belongs to the serpin family. (471 aa)
CR2Complement receptor type 2 isoform X1. (1471 aa)
LOC111184729Membrane cofactor protein-like isoform X1. (411 aa)
CD81Tetraspanin. (236 aa)
CD19B-lymphocyte antigen CD19 isoform X1. (570 aa)
CD59CD59 glycoprotein. (123 aa)
IRGQImmunity-related GTPase family Q protein isoform X1. (621 aa)
C5AR2C5a anaphylatoxin chemotactic receptor 2 isoform X1. (343 aa)
C5AR1C5a anaphylatoxin chemotactic receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (424 aa)
LOC111177076Ficolin-2-like isoform X1. (326 aa)
C8GComplement component C8 gamma chain isoform X1; Belongs to the calycin superfamily. Lipocalin family. (339 aa)
FIBCD1Fibrinogen C domain-containing protein 1. (461 aa)
C3AR1C3a anaphylatoxin chemotactic receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (498 aa)
C5Complement C5 isoform X1. (1677 aa)
LOC111177446LOW QUALITY PROTEIN: complement factor H-related protein 2-like. (278 aa)
C1RComplement C1r subcomponent isoform X1; Belongs to the peptidase S1 family. (713 aa)
LOC111177077Ficolin-1 isoform X1. (424 aa)
CFHComplement factor H isoform X1. (1236 aa)
C8AComplement component C8 alpha chain isoform X1. (589 aa)
SVEP1Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1. (3572 aa)
C1RLComplement C1r subcomponent-like protein isoform X1; Belongs to the peptidase S1 family. (523 aa)
C1SComplement C1s subcomponent; Belongs to the peptidase S1 family. (695 aa)
CPN1Carboxypeptidase N catalytic chain. (462 aa)
MASP1Mannan-binding lectin serine protease 1 isoform X1; Belongs to the peptidase S1 family. (739 aa)
MBL2LOW QUALITY PROTEIN: mannose-binding protein C. (244 aa)
CSMD1CUB and sushi domain-containing protein 1. (3564 aa)
C2Complement C2 isoform X1; Belongs to the peptidase S1 family. (751 aa)
CPN2Carboxypeptidase N subunit 2. (547 aa)
GZMMGranzyme M; Belongs to the peptidase S1 family. (257 aa)
CFBComplement factor B isoform X1; Belongs to the peptidase S1 family. (765 aa)
CFIComplement factor I; Belongs to the peptidase S1 family. (590 aa)
LOC111170700Complement C4-like isoform X1. (1740 aa)
ELANENeutrophil elastase; Belongs to the peptidase S1 family. (308 aa)
CFDComplement factor D; Belongs to the peptidase S1 family. (259 aa)
LOC111168646CD59 glycoprotein-like. (123 aa)
IGSF9Protein turtle homolog A. (1176 aa)
COLEC11Collectin-11. (267 aa)
LOC111166693T-cell-specific guanine nucleotide triphosphate-binding protein 1-like. (414 aa)
C3Complement C3 isoform X1. (1695 aa)
CFPProperdin. (464 aa)
IGSF9BProtein turtle homolog B isoform X1. (1616 aa)
LOC111166100Complement C3-like isoform X1. (1706 aa)
C1QBComplement C1q subcomponent subunit B. (290 aa)
LOC111163081LOW QUALITY PROTEIN: immunoglobulin lambda-1 light chain-like. (235 aa)
CSMD3CUB and sushi domain-containing protein 3 isoform X5. (3707 aa)
COLEC10Collectin-10 isoform X1. (277 aa)
C1QCComplement C1q subcomponent subunit C. (245 aa)
C1QAComplement C1q subcomponent subunit A. (245 aa)
FCN3LOW QUALITY PROTEIN: ficolin-3. (270 aa)
IGLL1Immunoglobulin lambda-like polypeptide 1 isoform X1. (212 aa)
CPB2Carboxypeptidase B2. (423 aa)
CSMD2CUB and sushi domain-containing protein 2. (3609 aa)
C8BComplement component C8 beta chain isoform X1. (590 aa)
LOC111184602Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. (367 aa)
LOC111184736Apolipoprotein R-like isoform X1. (189 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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