STRINGSTRING
GRB2 GRB2 PAG1 PAG1 TGFA TGFA FNDC3B FNDC3B PIK3CA PIK3CA FNDC3A FNDC3A CSK CSK TGFB1I1 TGFB1I1 HBEGF HBEGF LPXN LPXN SRC SRC BTC BTC LOC111187198 LOC111187198 PXN PXN PTPN11 PTPN11 GAB1 GAB1 EPGN EPGN EREG EREG PIK3R1 PIK3R1 AREG AREG RNF222 RNF222 EGFR EGFR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GRB2Growth factor receptor-bound protein 2. (217 aa)
PAG1Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 isoform X2. (436 aa)
TGFAProtransforming growth factor alpha isoform X1. (176 aa)
FNDC3BFibronectin type III domain-containing protein 3B isoform X1. (1215 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
FNDC3AFibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
CSKTyrosine-protein kinase. (528 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein isoform X1; Belongs to the paxillin family. (456 aa)
HBEGFProheparin-binding EGF-like growth factor. (208 aa)
LPXNLeupaxin isoform X2; Belongs to the paxillin family. (387 aa)
SRCTyrosine-protein kinase. (562 aa)
BTCProbetacellulin. (178 aa)
LOC111187198Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (617 aa)
PXNPaxillin isoform X2. (617 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
GAB1GRB2-associated-binding protein 1 isoform X1. (757 aa)
EPGNEpigen. (153 aa)
EREGProepiregulin. (163 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
AREGAmphiregulin isoform X1. (254 aa)
RNF222RING finger protein 222. (206 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.