16 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EREG	Proepiregulin. (163 aa)
	BTC	Probetacellulin. (178 aa)
	EPGN	Epigen. (153 aa)
	AREG	Amphiregulin isoform X1. (254 aa)
	EGFR	Receptor protein-tyrosine kinase. (1209 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	HBEGF	Proheparin-binding EGF-like growth factor. (208 aa)
	NRAS	GTPase NRas. (189 aa)
	CSDE1	Cold shock domain-containing protein E1 isoform X1. (798 aa)
	KRAS	GTPase KRas. (188 aa)
	SOS1	Son of sevenless homolog 1 isoform X1. (1333 aa)
	ERAS	GTPase ERas. (233 aa)
	HRAS	GTPase HRas isoform X1. (189 aa)
	TGFA	Protransforming growth factor alpha isoform X1. (176 aa)
	SHC1	SHC-transforming protein 1 isoform X1. (609 aa)
	LOC111165935	Ras-like protein isoform X1. (285 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AREG	BTC	A0A2Y9Q7W5	A0A2Y9QJ26	Amphiregulin isoform X1.	Probetacellulin.	0.840
AREG	EGFR	A0A2Y9Q7W5	A0A2Y9Q0F2	Amphiregulin isoform X1.	Receptor protein-tyrosine kinase.	0.994
AREG	EPGN	A0A2Y9Q7W5	A0A2Y9QC57	Amphiregulin isoform X1.	Epigen.	0.789
AREG	EREG	A0A2Y9Q7W5	A0A2Y9QC21	Amphiregulin isoform X1.	Proepiregulin.	0.885
AREG	GRB2	A0A2Y9Q7W5	A0A2Y9PJ90	Amphiregulin isoform X1.	Growth factor receptor-bound protein 2.	0.443
AREG	HBEGF	A0A2Y9Q7W5	A0A2Y9PFK7	Amphiregulin isoform X1.	Proheparin-binding EGF-like growth factor.	0.655
AREG	KRAS	A0A2Y9Q7W5	A0A2Y9NF08	Amphiregulin isoform X1.	GTPase KRas.	0.676
AREG	NRAS	A0A2Y9Q7W5	A0A2Y9PBA0	Amphiregulin isoform X1.	GTPase NRas.	0.424
AREG	TGFA	A0A2Y9Q7W5	A0A2Y9M4R3	Amphiregulin isoform X1.	Protransforming growth factor alpha isoform X1.	0.764
BTC	AREG	A0A2Y9QJ26	A0A2Y9Q7W5	Probetacellulin.	Amphiregulin isoform X1.	0.840
BTC	EGFR	A0A2Y9QJ26	A0A2Y9Q0F2	Probetacellulin.	Receptor protein-tyrosine kinase.	0.985
BTC	EPGN	A0A2Y9QJ26	A0A2Y9QC57	Probetacellulin.	Epigen.	0.817
BTC	EREG	A0A2Y9QJ26	A0A2Y9QC21	Probetacellulin.	Proepiregulin.	0.743
BTC	GRB2	A0A2Y9QJ26	A0A2Y9PJ90	Probetacellulin.	Growth factor receptor-bound protein 2.	0.450
BTC	HBEGF	A0A2Y9QJ26	A0A2Y9PFK7	Probetacellulin.	Proheparin-binding EGF-like growth factor.	0.822
BTC	KRAS	A0A2Y9QJ26	A0A2Y9NF08	Probetacellulin.	GTPase KRas.	0.528
BTC	TGFA	A0A2Y9QJ26	A0A2Y9M4R3	Probetacellulin.	Protransforming growth factor alpha isoform X1.	0.485
CSDE1	EGFR	A0A2Y9P0H2	A0A2Y9Q0F2	Cold shock domain-containing protein E1 isoform X1.	Receptor protein-tyrosine kinase.	0.500
CSDE1	GRB2	A0A2Y9P0H2	A0A2Y9PJ90	Cold shock domain-containing protein E1 isoform X1.	Growth factor receptor-bound protein 2.	0.565
CSDE1	SOS1	A0A2Y9P0H2	A0A2Y9N647	Cold shock domain-containing protein E1 isoform X1.	Son of sevenless homolog 1 isoform X1.	0.607