STRINGSTRING
TGFB1I1 TGFB1I1 ACTBL2 ACTBL2 CDC42 CDC42 ACTL8 ACTL8 ARVCF ARVCF STX12 STX12 WASF1 WASF1 FYN FYN WASF2 WASF2 ROCK2 ROCK2 LOC111165935 LOC111165935 VAV1 VAV1 SHD SHD EFS EFS JUP JUP PIK3R2 PIK3R2 STX7 STX7 PRKACA PRKACA SH2D2A SH2D2A PTK2 PTK2 PAK3 PAK3 TENM1 TENM1 SHE SHE HSH2D HSH2D CTNNB1 CTNNB1 LOC111169445 LOC111169445 THEM4 THEM4 LOC111170125 LOC111170125 ACTB ACTB HRAS HRAS VEGFD VEGFD ERAS ERAS ELMO2 ELMO2 DOCK1 DOCK1 ITGAV ITGAV ABI2 ABI2 NRP2 NRP2 KDR KDR BRK1 BRK1 PAK2 PAK2 SHC2 SHC2 FLT4 FLT4 FNDC3B FNDC3B PIK3CA PIK3CA VEGFC VEGFC NCKAP1L NCKAP1L NCKAP1 NCKAP1 FLT1 FLT1 HSP90AA1 HSP90AA1 PRKCD PRKCD MAPKAPK3 MAPKAPK3 RHOA RHOA FNDC3A FNDC3A PGF PGF NOS3 NOS3 KRAS KRAS VAV2 VAV2 ABI1 ABI1 MAPK14 MAPK14 VEGFA VEGFA CALM1 CALM1 LOC111178986 LOC111178986 NRP1 NRP1 NCK1 NCK1 MAPK13 MAPK13 LOC111179403 LOC111179403 PRKACB PRKACB BCAR1 BCAR1 PIK3CB PIK3CB CAV1 CAV1 CSDE1 CSDE1 CDH5 CDH5 AXL AXL VAV3 VAV3 ELMO1 ELMO1 NEDD9 NEDD9 ELMO3 ELMO3 NCF1 NCF1 ROCK1 ROCK1 NRAS NRAS ITGB3 ITGB3 HSPB1 HSPB1 CTNNA1 CTNNA1 PRKCB PRKCB CYFIP2 CYFIP2 SHF SHF PRKCA PRKCA ACTG1 ACTG1 SPHK1 SPHK1 LOC111181737 LOC111181737 RAC1 RAC1 CYFIP1 CYFIP1 PLCG1 PLCG1 BAIAP2 BAIAP2 LPXN LPXN CTNND1 CTNND1 RASA1 RASA1 NCF2 NCF2 TENM4 TENM4 SRC SRC MAPKAPK2 MAPKAPK2 PAK1 PAK1 VEGFB VEGFB CRK CRK PRR5 PRR5 PDPK1 PDPK1 MAPK12 MAPK12 PTK2B PTK2B RNF222 RNF222 PIK3R1 PIK3R1 PRKCZ PRKCZ MAPK11 MAPK11 LOC111186386 LOC111186386 NCK2 NCK2 CASS4 CASS4 LOC111187847 LOC111187847 PXN PXN SZRD1 SZRD1 RICTOR RICTOR SHB SHB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein isoform X1; Belongs to the paxillin family. (456 aa)
ACTBL2LOW QUALITY PROTEIN: beta-actin-like protein 2; Belongs to the actin family. (373 aa)
CDC42Cell division control protein 42 homolog isoform X2. (191 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (365 aa)
ARVCFArmadillo repeat protein deleted in velo-cardio-facial syndrome isoform X1. (960 aa)
STX12Syntaxin-12; Belongs to the syntaxin family. (274 aa)
WASF1wiskott-Aldrich syndrome protein family member 1. (559 aa)
FYNTyrosine-protein kinase. (537 aa)
WASF2wiskott-Aldrich syndrome protein family member 2. (498 aa)
ROCK2Rho-associated protein kinase 2 isoform X2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1416 aa)
LOC111165935Ras-like protein isoform X1. (285 aa)
VAV1Proto-oncogene vav isoform X1. (845 aa)
SHDSH2 domain-containing adapter protein D. (340 aa)
EFSEmbryonal Fyn-associated substrate isoform X2. (561 aa)
JUPJunction plakoglobin. (744 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
STX7Syntaxin-7 isoform X1; Belongs to the syntaxin family. (261 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
SH2D2ASH2 domain-containing protein 2A isoform X1. (449 aa)
PTK2Focal adhesion kinase 1 isoform X22; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1116 aa)
PAK3Non-specific serine/threonine protein kinase. (559 aa)
TENM1Teneurin-1 isoform X1. (2659 aa)
SHESH2 domain-containing adapter protein E. (499 aa)
HSH2DHematopoietic SH2 domain-containing protein isoform X1. (346 aa)
CTNNB1Catenin beta-1. (781 aa)
LOC111169445Acyl-coenzyme A thioesterase THEM4-like. (174 aa)
THEM4Acyl-coenzyme A thioesterase THEM4. (224 aa)
LOC111170125Myosin light chain 1, skeletal muscle isoform-like isoform X1; Belongs to the calmodulin family. (304 aa)
ACTBActin, cytoplasmic 1. (375 aa)
HRASGTPase HRas isoform X1. (189 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
ERASGTPase ERas. (233 aa)
ELMO2Engulfment and cell motility protein 2 isoform X1. (720 aa)
DOCK1Dedicator of cytokinesis protein 1 isoform X1; Belongs to the DOCK family. (1886 aa)
ITGAVIntegrin alpha-V isoform X2; Belongs to the integrin alpha chain family. (1048 aa)
ABI2Abl interactor 2 isoform X1. (544 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (931 aa)
KDRVascular endothelial growth factor receptor 2 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
BRK1Protein BRICK1. (75 aa)
PAK2Non-specific serine/threonine protein kinase. (523 aa)
SHC2SHC-transforming protein 2 isoform X1. (588 aa)
FLT4Vascular endothelial growth factor receptor 3 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1367 aa)
FNDC3BFibronectin type III domain-containing protein 3B isoform X1. (1215 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (420 aa)
NCKAP1LNck-associated protein 1-like isoform X1. (1156 aa)
NCKAP1Nck-associated protein 1 isoform X1. (1134 aa)
FLT1Vascular endothelial growth factor receptor 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1340 aa)
HSP90AA1Heat shock protein HSP 90-alpha. (733 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (733 aa)
MAPKAPK3MAP kinase-activated protein kinase 3 isoform X1; Belongs to the protein kinase superfamily. (384 aa)
RHOATransforming protein RhoA. (193 aa)
FNDC3AFibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
PGFPlacenta growth factor isoform X1; Belongs to the PDGF/VEGF growth factor family. (170 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
KRASGTPase KRas. (188 aa)
VAV2Guanine nucleotide exchange factor VAV2 isoform X1. (879 aa)
ABI1Abl interactor 1 isoform X1. (508 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
VEGFAVascular endothelial growth factor A isoform X1; Belongs to the PDGF/VEGF growth factor family. (214 aa)
CALM1Calmodulin-1; Belongs to the calmodulin family. (149 aa)
LOC111178986LOW QUALITY PROTEIN: catenin alpha-1-like. (908 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (924 aa)
NCK1Cytoplasmic protein. (377 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
LOC111179403Cytochrome b-245 light chain isoform X1. (202 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
BCAR1Breast cancer anti-estrogen resistance protein 1 isoform X4. (867 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
CDH5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (782 aa)
AXLLOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO. (887 aa)
VAV3Guanine nucleotide exchange factor VAV3. (954 aa)
ELMO1Engulfment and cell motility protein 1 isoform X1. (727 aa)
NEDD9Enhancer of filamentation 1 isoform X1. (829 aa)
ELMO3Engulfment and cell motility protein 3 isoform X1. (782 aa)
NCF1Neutrophil cytosol factor 1 isoform X2. (405 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
NRASGTPase NRas. (189 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (789 aa)
HSPB1Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (201 aa)
CTNNA1Catenin alpha-1. (906 aa)
PRKCBProtein kinase C. (689 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
SHFLOW QUALITY PROTEIN: SH2 domain-containing adapter protein F. (489 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (670 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
SPHK1Sphingosine kinase 1 isoform X2. (484 aa)
LOC111181737Syntaxin-12-like; Belongs to the syntaxin family. (278 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (192 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
BAIAP2Brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X2. (522 aa)
LPXNLeupaxin isoform X2; Belongs to the paxillin family. (387 aa)
CTNND1Catenin delta-1 isoform X1. (961 aa)
RASA1Ras GTPase-activating protein 1 isoform X1. (1040 aa)
NCF2Neutrophil cytosol factor 2 isoform X1. (526 aa)
TENM4Teneurin-4 isoform X1. (2864 aa)
SRCTyrosine-protein kinase. (562 aa)
MAPKAPK2LOW QUALITY PROTEIN: MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (414 aa)
PAK1Non-specific serine/threonine protein kinase. (543 aa)
VEGFBVascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (209 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
PRR5Proline-rich protein 5 isoform X1. (389 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
MAPK12Mitogen-activated protein kinase. (456 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1015 aa)
RNF222RING finger protein 222. (206 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (629 aa)
MAPK11Mitogen-activated protein kinase. (366 aa)
LOC111186386Neutrophil cytosol factor 4-like. (250 aa)
NCK2Cytoplasmic protein. (376 aa)
CASS4Cas scaffolding protein family member 4 isoform X1. (821 aa)
LOC111187847Neutrophil cytosol factor 4 isoform X2. (339 aa)
PXNPaxillin isoform X2. (617 aa)
SZRD1SUZ domain-containing protein 1 isoform X5. (171 aa)
RICTORRapamycin-insensitive companion of mTOR isoform X1. (1732 aa)
SHBSH2 domain-containing adapter protein B. (507 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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