STRINGSTRING
SZRD1 SZRD1 PXN PXN LOC111187847 LOC111187847 CASS4 CASS4 NCK2 NCK2 LOC111186386 LOC111186386 MAPK11 MAPK11 PRKCZ PRKCZ PIK3R1 PIK3R1 RNF222 RNF222 PTK2B PTK2B MAPK12 MAPK12 PDPK1 PDPK1 PRR5 PRR5 CRK CRK VEGFB VEGFB PAK1 PAK1 MAPKAPK2 MAPKAPK2 SRC SRC TENM4 TENM4 NCF2 NCF2 RASA1 RASA1 CTNND1 CTNND1 PGF PGF FNDC3A FNDC3A RHOA RHOA CALM1 CALM1 MAPKAPK3 MAPKAPK3 PRKCD PRKCD HSP90AA1 HSP90AA1 FLT1 FLT1 NCKAP1 NCKAP1 NCKAP1L NCKAP1L PRKACA PRKACA STX7 STX7 PIK3R2 PIK3R2 JUP JUP EFS EFS SHD SHD VAV1 VAV1 LOC111165935 LOC111165935 ROCK2 ROCK2 WASF2 WASF2 FYN FYN WASF1 WASF1 STX12 STX12 ARVCF ARVCF ACTL8 ACTL8 CDC42 CDC42 ACTBL2 ACTBL2 VEGFC VEGFC PIK3CA PIK3CA FNDC3B FNDC3B FLT4 FLT4 SHC2 SHC2 PAK2 PAK2 BRK1 BRK1 KDR KDR NRP2 NRP2 ABI2 ABI2 ITGAV ITGAV LPXN LPXN BAIAP2 BAIAP2 PLCG1 PLCG1 CYFIP1 CYFIP1 RAC1 RAC1 LOC111181737 LOC111181737 SPHK1 SPHK1 ACTG1 ACTG1 PRKCA PRKCA SHF SHF CYFIP2 CYFIP2 PRKCB PRKCB CTNNA1 CTNNA1 TGFB1I1 TGFB1I1 HSPB1 HSPB1 ITGB3 ITGB3 NRAS NRAS ROCK1 ROCK1 NCF1 NCF1 ELMO3 ELMO3 NEDD9 NEDD9 ELMO1 ELMO1 VAV3 VAV3 AXL AXL CDH5 CDH5 CSDE1 CSDE1 CAV1 CAV1 PIK3CB PIK3CB BCAR1 BCAR1 PRKACB PRKACB LOC111179403 LOC111179403 MAPK13 MAPK13 NCK1 NCK1 NRP1 NRP1 LOC111178986 LOC111178986 DOCK1 DOCK1 ELMO2 ELMO2 ERAS ERAS VEGFD VEGFD HRAS HRAS ACTB ACTB LOC111170125 LOC111170125 THEM4 THEM4 LOC111169445 LOC111169445 CTNNB1 CTNNB1 HSH2D HSH2D SHE SHE TENM1 TENM1 PAK3 PAK3 PTK2 PTK2 SH2D2A SH2D2A VEGFA VEGFA MAPK14 MAPK14 ABI1 ABI1 VAV2 VAV2 KRAS KRAS NOS3 NOS3 SHB SHB RICTOR RICTOR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SZRD1SUZ domain-containing protein 1 isoform X5. (171 aa)
PXNPaxillin isoform X2. (617 aa)
LOC111187847Neutrophil cytosol factor 4 isoform X2. (339 aa)
CASS4Cas scaffolding protein family member 4 isoform X1. (821 aa)
NCK2Cytoplasmic protein. (376 aa)
LOC111186386Neutrophil cytosol factor 4-like. (250 aa)
MAPK11Mitogen-activated protein kinase. (366 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (629 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
RNF222RING finger protein 222. (206 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1015 aa)
MAPK12Mitogen-activated protein kinase. (456 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
PRR5Proline-rich protein 5 isoform X1. (389 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
VEGFBVascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (209 aa)
PAK1Non-specific serine/threonine protein kinase. (543 aa)
MAPKAPK2LOW QUALITY PROTEIN: MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (414 aa)
SRCTyrosine-protein kinase. (562 aa)
TENM4Teneurin-4 isoform X1. (2864 aa)
NCF2Neutrophil cytosol factor 2 isoform X1. (526 aa)
RASA1Ras GTPase-activating protein 1 isoform X1. (1040 aa)
CTNND1Catenin delta-1 isoform X1. (961 aa)
PGFPlacenta growth factor isoform X1; Belongs to the PDGF/VEGF growth factor family. (170 aa)
FNDC3AFibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
RHOATransforming protein RhoA. (193 aa)
CALM1Calmodulin-1; Belongs to the calmodulin family. (149 aa)
MAPKAPK3MAP kinase-activated protein kinase 3 isoform X1; Belongs to the protein kinase superfamily. (384 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (733 aa)
HSP90AA1Heat shock protein HSP 90-alpha. (733 aa)
FLT1Vascular endothelial growth factor receptor 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1340 aa)
NCKAP1Nck-associated protein 1 isoform X1. (1134 aa)
NCKAP1LNck-associated protein 1-like isoform X1. (1156 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
STX7Syntaxin-7 isoform X1; Belongs to the syntaxin family. (261 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
JUPJunction plakoglobin. (744 aa)
EFSEmbryonal Fyn-associated substrate isoform X2. (561 aa)
SHDSH2 domain-containing adapter protein D. (340 aa)
VAV1Proto-oncogene vav isoform X1. (845 aa)
LOC111165935Ras-like protein isoform X1. (285 aa)
ROCK2Rho-associated protein kinase 2 isoform X2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1416 aa)
WASF2wiskott-Aldrich syndrome protein family member 2. (498 aa)
FYNTyrosine-protein kinase. (537 aa)
WASF1wiskott-Aldrich syndrome protein family member 1. (559 aa)
STX12Syntaxin-12; Belongs to the syntaxin family. (274 aa)
ARVCFArmadillo repeat protein deleted in velo-cardio-facial syndrome isoform X1. (960 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (365 aa)
CDC42Cell division control protein 42 homolog isoform X2. (191 aa)
ACTBL2LOW QUALITY PROTEIN: beta-actin-like protein 2; Belongs to the actin family. (373 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (420 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
FNDC3BFibronectin type III domain-containing protein 3B isoform X1. (1215 aa)
FLT4Vascular endothelial growth factor receptor 3 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1367 aa)
SHC2SHC-transforming protein 2 isoform X1. (588 aa)
PAK2Non-specific serine/threonine protein kinase. (523 aa)
BRK1Protein BRICK1. (75 aa)
KDRVascular endothelial growth factor receptor 2 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (931 aa)
ABI2Abl interactor 2 isoform X1. (544 aa)
ITGAVIntegrin alpha-V isoform X2; Belongs to the integrin alpha chain family. (1048 aa)
LPXNLeupaxin isoform X2; Belongs to the paxillin family. (387 aa)
BAIAP2Brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X2. (522 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (192 aa)
LOC111181737Syntaxin-12-like; Belongs to the syntaxin family. (278 aa)
SPHK1Sphingosine kinase 1 isoform X2. (484 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (670 aa)
SHFLOW QUALITY PROTEIN: SH2 domain-containing adapter protein F. (489 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
PRKCBProtein kinase C. (689 aa)
CTNNA1Catenin alpha-1. (906 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein isoform X1; Belongs to the paxillin family. (456 aa)
HSPB1Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (201 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (789 aa)
NRASGTPase NRas. (189 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
NCF1Neutrophil cytosol factor 1 isoform X2. (405 aa)
ELMO3Engulfment and cell motility protein 3 isoform X1. (782 aa)
NEDD9Enhancer of filamentation 1 isoform X1. (829 aa)
ELMO1Engulfment and cell motility protein 1 isoform X1. (727 aa)
VAV3Guanine nucleotide exchange factor VAV3. (954 aa)
AXLLOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO. (887 aa)
CDH5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (782 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
BCAR1Breast cancer anti-estrogen resistance protein 1 isoform X4. (867 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
LOC111179403Cytochrome b-245 light chain isoform X1. (202 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
NCK1Cytoplasmic protein. (377 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (924 aa)
LOC111178986LOW QUALITY PROTEIN: catenin alpha-1-like. (908 aa)
DOCK1Dedicator of cytokinesis protein 1 isoform X1; Belongs to the DOCK family. (1886 aa)
ELMO2Engulfment and cell motility protein 2 isoform X1. (720 aa)
ERASGTPase ERas. (233 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
HRASGTPase HRas isoform X1. (189 aa)
ACTBActin, cytoplasmic 1. (375 aa)
LOC111170125Myosin light chain 1, skeletal muscle isoform-like isoform X1; Belongs to the calmodulin family. (304 aa)
THEM4Acyl-coenzyme A thioesterase THEM4. (224 aa)
LOC111169445Acyl-coenzyme A thioesterase THEM4-like. (174 aa)
CTNNB1Catenin beta-1. (781 aa)
HSH2DHematopoietic SH2 domain-containing protein isoform X1. (346 aa)
SHESH2 domain-containing adapter protein E. (499 aa)
TENM1Teneurin-1 isoform X1. (2659 aa)
PAK3Non-specific serine/threonine protein kinase. (559 aa)
PTK2Focal adhesion kinase 1 isoform X22; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1116 aa)
SH2D2ASH2 domain-containing protein 2A isoform X1. (449 aa)
VEGFAVascular endothelial growth factor A isoform X1; Belongs to the PDGF/VEGF growth factor family. (214 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
ABI1Abl interactor 1 isoform X1. (508 aa)
VAV2Guanine nucleotide exchange factor VAV2 isoform X1. (879 aa)
KRASGTPase KRas. (188 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
SHBSH2 domain-containing adapter protein B. (507 aa)
RICTORRapamycin-insensitive companion of mTOR isoform X1. (1732 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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