10 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PIK3R2	Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	RHOA	Transforming protein RhoA. (193 aa)
	IRS2	Insulin receptor substrate 2. (1347 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
	NGF	Beta-nerve growth factor; Belongs to the NGF-beta family. (241 aa)
	NTRK1	Tyrosine-protein kinase receptor. (795 aa)
	LOC111181964	Uncharacterized protein LOC111181964 isoform X1. (833 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	IRS1	Insulin receptor substrate 1. (1248 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IRS1	IRS2	A0A2Y9MMM9	A0A2Y9NC55	Insulin receptor substrate 1.	Insulin receptor substrate 2.	0.944
IRS1	NGF	A0A2Y9MMM9	A0A2Y9PB93	Insulin receptor substrate 1.	Beta-nerve growth factor; Belongs to the NGF-beta family.	0.415
IRS1	NTRK1	A0A2Y9MMM9	A0A2Y9M0L7	Insulin receptor substrate 1.	Tyrosine-protein kinase receptor.	0.967
IRS1	PIK3CA	A0A2Y9MMM9	A0A2Y9MZW2	Insulin receptor substrate 1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.972
IRS1	PIK3CB	A0A2Y9MMM9	A0A2Y9NZC3	Insulin receptor substrate 1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.958
IRS1	PIK3R1	A0A2Y9MMM9	A0A2Y9Q8T5	Insulin receptor substrate 1.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.974
IRS1	PIK3R2	A0A2Y9MMM9	A0A2Y9LXY5	Insulin receptor substrate 1.	Phosphatidylinositol 3-kinase regulatory subunit beta.	0.967
IRS2	IRS1	A0A2Y9NC55	A0A2Y9MMM9	Insulin receptor substrate 2.	Insulin receptor substrate 1.	0.944
IRS2	NTRK1	A0A2Y9NC55	A0A2Y9M0L7	Insulin receptor substrate 2.	Tyrosine-protein kinase receptor.	0.688
IRS2	PIK3CA	A0A2Y9NC55	A0A2Y9MZW2	Insulin receptor substrate 2.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.961
IRS2	PIK3CB	A0A2Y9NC55	A0A2Y9NZC3	Insulin receptor substrate 2.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.958
IRS2	PIK3R1	A0A2Y9NC55	A0A2Y9Q8T5	Insulin receptor substrate 2.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.971
IRS2	PIK3R2	A0A2Y9NC55	A0A2Y9LXY5	Insulin receptor substrate 2.	Phosphatidylinositol 3-kinase regulatory subunit beta.	0.965
LOC111181964	NTRK1	A0A2Y9PK20	A0A2Y9M0L7	Uncharacterized protein LOC111181964 isoform X1.	Tyrosine-protein kinase receptor.	0.688
LOC111181964	PIK3CA	A0A2Y9PK20	A0A2Y9MZW2	Uncharacterized protein LOC111181964 isoform X1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.866
LOC111181964	PIK3CB	A0A2Y9PK20	A0A2Y9NZC3	Uncharacterized protein LOC111181964 isoform X1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.853
LOC111181964	PIK3R1	A0A2Y9PK20	A0A2Y9Q8T5	Uncharacterized protein LOC111181964 isoform X1.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.898
LOC111181964	PIK3R2	A0A2Y9PK20	A0A2Y9LXY5	Uncharacterized protein LOC111181964 isoform X1.	Phosphatidylinositol 3-kinase regulatory subunit beta.	0.878
NGF	IRS1	A0A2Y9PB93	A0A2Y9MMM9	Beta-nerve growth factor; Belongs to the NGF-beta family.	Insulin receptor substrate 1.	0.415
NGF	NTRK1	A0A2Y9PB93	A0A2Y9M0L7	Beta-nerve growth factor; Belongs to the NGF-beta family.	Tyrosine-protein kinase receptor.	0.996