STRINGSTRING
PSMA7 PSMA7 PSMD9 PSMD9 CD4 CD4 RELA RELA PSMC3 PSMC3 PSMD12 PSMD12 PAK1 PAK1 PSMF1 PSMF1 PSMA2 PSMA2 LOC111186271 LOC111186271 RPS27A RPS27A LAT LAT LOC111186752 LOC111186752 LOC111186270 LOC111186270 PDPK1 PDPK1 FBXW11 FBXW11 PSMD3 PSMD3 KXD1 KXD1 LOC111166275 LOC111166275 PSMD10 PSMD10 LCP2 LCP2 LOC111187417 LOC111187417 PSMD11 PSMD11 PSMB6 PSMB6 PIK3R1 PIK3R1 PSME4 PSME4 PSMB5 PSMB5 MAP3K7 MAP3K7 PSME1 PSME1 PSME2 PSME2 PSMA1 PSMA1 PAG1 PAG1 PSMB11 PSMB11 PSMC2 PSMC2 PSMC1 PSMC1 MAP3K20 MAP3K20 PTEN PTEN PSMD6 PSMD6 IKBKB IKBKB CHUK CHUK PIK3CA PIK3CA INPP5D INPP5D PSMA3 PSMA3 PSMA6 PSMA6 PSMC6 PSMC6 PSMD14 PSMD14 PAK2 PAK2 IKBKG IKBKG PSMD1 PSMD1 PSMD4 PSMD4 LOC111171742 LOC111171742 CARD11 CARD11 PSMB4 PSMB4 PSMD13 PSMD13 CD247 CD247 WAS WAS LOC111166421 LOC111166421 PTPRC PTPRC PSMB1 PSMB1 PAK3 PAK3 CD3E CD3E CD3G CD3G CD3D CD3D PSMB3 PSMB3 CCDC71L CCDC71L TAB2 TAB2 PIK3R2 PIK3R2 NFKBIA NFKBIA PSMB2 PSMB2 LCK LCK CSK CSK PSMD5 PSMD5 PSMB9 PSMB9 LOC111178928 LOC111178928 LOC111178931 LOC111178931 PRKCQ PRKCQ PSMB7 PSMB7 NCK1 NCK1 LOC111178925 LOC111178925 LOC111178929 LOC111178929 PSMD7 PSMD7 PLCG2 PLCG2 PSMA5 PSMA5 PIK3CB PIK3CB PSMA4 PSMA4 PSMC4 PSMC4 BCL10 BCL10 NFKB1 NFKB1 PSMB8 PSMB8 LOC111178927 LOC111178927 PSMB10 PSMB10 PSMD8 PSMD8 CD101 CD101 MALT1 MALT1 TRAF6 TRAF6 PTPN22 PTPN22 PSMA8 PSMA8 PSMC5 PSMC5 ITK ITK SPNS1 SPNS1 PLCG1 PLCG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMA7Proteasome subunit alpha type. (248 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9 isoform X1. (223 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (455 aa)
RELATranscription factor p65 isoform X1. (562 aa)
PSMC326S proteasome regulatory subunit 6A isoform X1; Belongs to the AAA ATPase family. (423 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12. (456 aa)
PAK1Non-specific serine/threonine protein kinase. (543 aa)
PSMF1Proteasome inhibitor PI31 subunit isoform X1. (270 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
LOC111186271GRB2-related adapter protein 2-like isoform X1. (105 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
LATLinker for activation of T-cells family member 1 isoform X1. (270 aa)
LOC111186752T-cell receptor-associated transmembrane adapter 1. (185 aa)
LOC111186270GRB2-related adapter protein 2 isoform X1. (337 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
FBXW11F-box/WD repeat-containing protein 11 isoform X1. (563 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (534 aa)
KXD1kxDL motif-containing protein 1 isoform X1. (196 aa)
LOC111166275Proteasome activator complex subunit 3-like. (165 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
LCP2Lymphocyte cytosolic protein 2 isoform X1. (534 aa)
LOC111187417Tyrosine-protein kinase. (612 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (422 aa)
PSMB6Proteasome subunit beta. (239 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
PSME4LOW QUALITY PROTEIN: proteasome activator complex subunit 4. (1845 aa)
PSMB5Proteasome subunit beta. (263 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
PSME1Proteasome activator complex subunit 1. (249 aa)
PSME2Proteasome activator complex subunit 2. (239 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
PAG1Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 isoform X2. (436 aa)
PSMB11Proteasome subunit beta. (291 aa)
PSMC226S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
PSMC126S proteasome regulatory subunit 4 isoform X1; Belongs to the AAA ATPase family. (440 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20 isoform X1. (800 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6 isoform X1. (452 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (882 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1150 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMC626S proteasome regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14 isoform X1. (310 aa)
PAK2Non-specific serine/threonine protein kinase. (523 aa)
IKBKGNF-kappa-B essential modulator isoform X1. (412 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (954 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform X1. (380 aa)
LOC111171742Ubiquitin-conjugating enzyme E2 variant 1. (147 aa)
CARD11Caspase recruitment domain-containing protein 11 isoform X1. (1154 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
CD247T-cell surface glycoprotein CD3 zeta chain isoform X1. (185 aa)
WASwiskott-Aldrich syndrome protein. (502 aa)
LOC111166421Proteasome activator complex subunit 3. (254 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C isoform X1. (1258 aa)
PSMB1Proteasome subunit beta. (241 aa)
PAK3Non-specific serine/threonine protein kinase. (559 aa)
CD3ET-cell surface glycoprotein CD3 epsilon chain. (197 aa)
CD3GT-cell surface glycoprotein CD3 gamma chain. (178 aa)
CD3DT-cell surface glycoprotein CD3 delta chain. (171 aa)
PSMB3Proteasome subunit beta. (205 aa)
CCDC71LCoiled-coil domain-containing protein 71L. (237 aa)
TAB2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1. (693 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
NFKBIANF-kappa-B inhibitor alpha. (314 aa)
PSMB2Proteasome subunit beta. (201 aa)
LCKTyrosine-protein kinase. (509 aa)
CSKTyrosine-protein kinase. (528 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5. (504 aa)
PSMB9Proteasome subunit beta. (219 aa)
LOC111178928DLA class II histocompatibility antigen, DR-1 beta chain-like. (266 aa)
LOC111178931HLA class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. (253 aa)
PRKCQProtein kinase C. (665 aa)
PSMB7Proteasome subunit beta. (277 aa)
NCK1Cytoplasmic protein. (377 aa)
LOC111178925boLa class II histocompatibility antigen, DQB*0101 beta chain-like isoform X2. (276 aa)
LOC111178929HLA class II histocompatibility antigen, DRB1-4 beta chain-like isoform X1. (231 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (322 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSMC426S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
BCL10B-cell lymphoma/leukemia 10. (233 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa)
PSMB8Proteasome subunit beta. (276 aa)
LOC111178927HLA class II histocompatibility antigen, DQ alpha 2 chain; Belongs to the MHC class II family. (255 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (351 aa)
CD101Immunoglobulin superfamily member 2 isoform X1. (1018 aa)
MALT1Mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X1. (850 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa)
PTPN22Tyrosine-protein phosphatase non-receptor type 22 isoform X1. (801 aa)
PSMA8Proteasome subunit alpha type. (269 aa)
PSMC526S proteasome regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
ITKTyrosine-protein kinase. (620 aa)
SPNS1Protein spinster homolog 1 isoform X1. (606 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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