17 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SRC	Tyrosine-protein kinase. (562 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (789 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	LOC111187198	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (617 aa)
	LYN	Tyrosine-protein kinase. (518 aa)
	ITGAV	Integrin alpha-V isoform X2; Belongs to the integrin alpha chain family. (1048 aa)
	INPP5D	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1150 aa)
	FNDC3B	Fibronectin type III domain-containing protein 3B isoform X1. (1215 aa)
	FNDC3A	Fibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	LCK	Tyrosine-protein kinase. (509 aa)
	YES1	Tyrosine-protein kinase. (541 aa)
	LOC111182630	Platelet endothelial cell adhesion molecule-like isoform X2. (305 aa)
	MILR1	Allergin-1 isoform X1. (318 aa)
	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
	PECAM1	Platelet endothelial cell adhesion molecule isoform X1. (701 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FYN	LCK	A0A2Y9LLH3	A0A2Y9NNB7	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.959
FYN	LOC111187198	A0A2Y9LLH3	A0A2Y9QG58	Tyrosine-protein kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.540
FYN	LYN	A0A2Y9LLH3	A0A2Y9LZZ2	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.985
FYN	PLCG1	A0A2Y9LLH3	A0A2Y9PMG8	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.606
FYN	PTPN11	A0A2Y9LLH3	A0A2Y9QEG1	Tyrosine-protein kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.609
FYN	PTPN6	A0A2Y9LLH3	A0A2Y9NJV6	Tyrosine-protein kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.646
FYN	SRC	A0A2Y9LLH3	A0A2Y9PSD7	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.962
FYN	YES1	A0A2Y9LLH3	A0A2Y9PB67	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.957
INPP5D	LCK	A0A2Y9MYB1	A0A2Y9NNB7	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1.	Tyrosine-protein kinase.	0.457
INPP5D	LOC111182630	A0A2Y9MYB1	A0A2Y9PGA8	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1.	Platelet endothelial cell adhesion molecule-like isoform X2.	0.856
INPP5D	LOC111187198	A0A2Y9MYB1	A0A2Y9QG58	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.575
INPP5D	LYN	A0A2Y9MYB1	A0A2Y9LZZ2	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1.	Tyrosine-protein kinase.	0.686
INPP5D	MILR1	A0A2Y9MYB1	A0A2Y9PHY3	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1.	Allergin-1 isoform X1.	0.587
INPP5D	PECAM1	A0A2Y9MYB1	A0A2Y9PNJ4	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1.	Platelet endothelial cell adhesion molecule isoform X1.	0.856
INPP5D	PTPN11	A0A2Y9MYB1	A0A2Y9QEG1	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.575
INPP5D	PTPN6	A0A2Y9MYB1	A0A2Y9NJV6	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.708
INPP5D	SRC	A0A2Y9MYB1	A0A2Y9PSD7	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1.	Tyrosine-protein kinase.	0.449
INPP5D	YES1	A0A2Y9MYB1	A0A2Y9PB67	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1.	Tyrosine-protein kinase.	0.449
ITGAV	ITGB3	A0A2Y9MPN9	A0A2Y9PCY7	Integrin alpha-V isoform X2; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.999
ITGAV	LOC111182630	A0A2Y9MPN9	A0A2Y9PGA8	Integrin alpha-V isoform X2; Belongs to the integrin alpha chain family.	Platelet endothelial cell adhesion molecule-like isoform X2.	0.715