STRINGSTRING
LOC111164311 LOC111164311 ARNT2 ARNT2 CCDC160 CCDC160 LOC111165853 LOC111165853 LOC111165107 LOC111165107 FDX1L FDX1L FDX1 FDX1 LOC111170861 LOC111170861 LOC111171015 LOC111171015 ARNT ARNT LOC111170705 LOC111170705 LOC111171838 LOC111171838 LOC111170860 LOC111170860 NCOA1 NCOA1 POMC POMC LOC111173427 LOC111173427 LOC111174870 LOC111174870 LOC111176091 LOC111176091 RXRA RXRA LOC111177811 LOC111177811 AHRR AHRR LOC111178887 LOC111178887 LOC111180826 LOC111180826 FADS6 FADS6 FDXR FDXR NCOA2 NCOA2 LOC111185591 LOC111185591 NR1H4 NR1H4 AHR AHR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC1111643115-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase; Belongs to the cytochrome P450 family. (511 aa)
ARNT2Aryl hydrocarbon receptor nuclear translocator 2 isoform X1. (717 aa)
CCDC160Coiled-coil domain-containing protein 160. (325 aa)
LOC111165853Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (501 aa)
LOC111165107Cytochrome P450 11B1, mitochondrial isoform X1; Belongs to the cytochrome P450 family. (503 aa)
FDX1LFerredoxin-2, mitochondrial isoform X2. (193 aa)
FDX1Adrenodoxin, mitochondrial. (193 aa)
LOC111170861Aromatase-like. (388 aa)
LOC111171015Aromatase-like; Belongs to the cytochrome P450 family. (296 aa)
ARNTAryl hydrocarbon receptor nuclear translocator isoform X1. (790 aa)
LOC111170705Steroid 21-hydroxylase; Belongs to the cytochrome P450 family. (495 aa)
LOC111171838Sterol 26-hydroxylase, mitochondrial isoform X1; Belongs to the cytochrome P450 family. (571 aa)
LOC111170860Aromatase; Belongs to the cytochrome P450 family. (503 aa)
NCOA1Nuclear receptor coactivator. (1441 aa)
POMCPro-opiomelanocortin. (261 aa)
LOC111173427Cytochrome P450 4V2; Belongs to the cytochrome P450 family. (652 aa)
LOC111174870Cytochrome P450 1B1; Belongs to the cytochrome P450 family. (543 aa)
LOC111176091Cholesterol 24-hydroxylase isoform X1; Belongs to the cytochrome P450 family. (501 aa)
RXRARetinoic acid receptor RXR-alpha isoform X1. (495 aa)
LOC111177811Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (520 aa)
AHRRAryl hydrocarbon receptor repressor. (693 aa)
LOC11117888724-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (469 aa)
LOC111180826Lanosterol 14-alpha demethylase isoform X1; Belongs to the cytochrome P450 family. (503 aa)
FADS6Fatty acid desaturase 6 isoform X1. (456 aa)
FDXRNADPH:adrenodoxin oxidoreductase, mitochondrial. (523 aa)
NCOA2Nuclear receptor coactivator. (1464 aa)
LOC11118559125-hydroxycholesterol 7-alpha-hydroxylase isoform X1; Belongs to the cytochrome P450 family. (502 aa)
NR1H4Bile acid receptor isoform X1. (486 aa)
AHRAryl hydrocarbon receptor; Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing [...] (845 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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