35 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FYN	Tyrosine-protein kinase. (537 aa)
	LOC111165935	Ras-like protein isoform X1. (285 aa)
	PIK3R2	Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
	SHC1	SHC-transforming protein 1 isoform X1. (609 aa)
	SYK	Tyrosine-protein kinase. (626 aa)
	HRAS	GTPase HRas isoform X1. (189 aa)
	LOC111171351	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (113 aa)
	ERAS	GTPase ERas. (233 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	SOS1	Son of sevenless homolog 1 isoform X1. (1333 aa)
	LOC111176758	NKG2-A/NKG2-B type II integral membrane protein-like isoform X1. (256 aa)
	KRAS	GTPase KRas. (188 aa)
	VAV2	Guanine nucleotide exchange factor VAV2 isoform X1. (879 aa)
	KLRD1	Natural killer cells antigen CD94 isoform X1. (240 aa)
	LCK	Tyrosine-protein kinase. (509 aa)
	BTK	Tyrosine-protein kinase. (687 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
	CSDE1	Cold shock domain-containing protein E1 isoform X1. (798 aa)
	TREM2	Triggering receptor expressed on myeloid cells 2. (294 aa)
	VAV3	Guanine nucleotide exchange factor VAV3. (954 aa)
	NRAS	GTPase NRas. (189 aa)
	TYROBP	TYRO protein tyrosine kinase-binding protein isoform X1. (126 aa)
	LOC111181647	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (118 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	LOC111181648	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (118 aa)
	RAC1	Ras-related C3 botulinum toxin substrate 1. (192 aa)
	SPNS1	Protein spinster homolog 1 isoform X1. (606 aa)
	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
	LAT	Linker for activation of T-cells family member 1 isoform X1. (270 aa)
	LOC111184277	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (118 aa)
	LOC111186271	GRB2-related adapter protein 2-like isoform X1. (105 aa)
	LOC111186270	GRB2-related adapter protein 2 isoform X1. (337 aa)
	LCP2	Lymphocyte cytosolic protein 2 isoform X1. (534 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTK	FYN	A0A2Y9NR66	A0A2Y9LLH3	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.514
BTK	GRB2	A0A2Y9NR66	A0A2Y9PJ90	Tyrosine-protein kinase.	Growth factor receptor-bound protein 2.	0.787
BTK	LAT	A0A2Y9NR66	A0A2Y9PN07	Tyrosine-protein kinase.	Linker for activation of T-cells family member 1 isoform X1.	0.502
BTK	LCK	A0A2Y9NR66	A0A2Y9NNB7	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.518
BTK	LCP2	A0A2Y9NR66	A0A2Y9Q5Y1	Tyrosine-protein kinase.	Lymphocyte cytosolic protein 2 isoform X1.	0.980
BTK	LOC111186270	A0A2Y9NR66	A0A2Y9Q410	Tyrosine-protein kinase.	GRB2-related adapter protein 2 isoform X1.	0.606
BTK	LOC111186271	A0A2Y9NR66	A0A2Y9Q010	Tyrosine-protein kinase.	GRB2-related adapter protein 2-like isoform X1.	0.606
BTK	PIK3CA	A0A2Y9NR66	A0A2Y9MZW2	Tyrosine-protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.948
BTK	PIK3CB	A0A2Y9NR66	A0A2Y9NZC3	Tyrosine-protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.940
BTK	PIK3R1	A0A2Y9NR66	A0A2Y9Q8T5	Tyrosine-protein kinase.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.937
BTK	PIK3R2	A0A2Y9NR66	A0A2Y9LXY5	Tyrosine-protein kinase.	Phosphatidylinositol 3-kinase regulatory subunit beta.	0.932
BTK	PLCG1	A0A2Y9NR66	A0A2Y9PMG8	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.969
BTK	PLCG2	A0A2Y9NR66	A0A2Y9NXP3	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.990
BTK	SHC1	A0A2Y9NR66	A0A2Y9LZK9	Tyrosine-protein kinase.	SHC-transforming protein 1 isoform X1.	0.608
BTK	SOS1	A0A2Y9NR66	A0A2Y9N647	Tyrosine-protein kinase.	Son of sevenless homolog 1 isoform X1.	0.474
BTK	SYK	A0A2Y9NR66	A0A2Y9MGM5	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.973
BTK	TYROBP	A0A2Y9NR66	A0A2Y9PHN5	Tyrosine-protein kinase.	TYRO protein tyrosine kinase-binding protein isoform X1.	0.503
BTK	VAV2	A0A2Y9NR66	A0A2Y9NG52	Tyrosine-protein kinase.	Guanine nucleotide exchange factor VAV2 isoform X1.	0.702
BTK	VAV3	A0A2Y9NR66	A0A2Y9P3S9	Tyrosine-protein kinase.	Guanine nucleotide exchange factor VAV3.	0.671
CSDE1	GRB2	A0A2Y9P0H2	A0A2Y9PJ90	Cold shock domain-containing protein E1 isoform X1.	Growth factor receptor-bound protein 2.	0.565