43 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HBB	Hemoglobin subunit beta; Belongs to the globin family. (147 aa)
	IGLL1	Immunoglobulin lambda-like polypeptide 1 isoform X1. (212 aa)
	SCARF2	Scavenger receptor class F member 2 isoform X1. (871 aa)
	LOC111163081	LOW QUALITY PROTEIN: immunoglobulin lambda-1 light chain-like. (235 aa)
	LOC111163515	Uncharacterized protein LOC111163515. (1806 aa)
	LOC111164621	Platelet glycoprotein 4; Belongs to the CD36 family. (472 aa)
	LOC111164620	Platelet glycoprotein 4-like; Belongs to the CD36 family. (472 aa)
	CALR3	Calreticulin. (385 aa)
	APOA1	Apolipoprotein A-I. (265 aa)
	HYOU1	Hypoxia up-regulated protein 1 isoform X1. (998 aa)
	LOC111166693	T-cell-specific guanine nucleotide triphosphate-binding protein 1-like. (414 aa)
	COLEC11	Collectin-11. (267 aa)
	CALR	Calreticulin. (417 aa)
	HPX	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (455 aa)
	CD5L	CD5 antigen-like. (341 aa)
	LRP1B	Low-density lipoprotein receptor-related protein 1B isoform X1. (4679 aa)
	MASP1	Mannan-binding lectin serine protease 1 isoform X1; Belongs to the peptidase S1 family. (739 aa)
	LOC111172230	Deleted in malignant brain tumors 1 protein isoform X1. (684 aa)
	STAB1	Stabilin-1 isoform X1. (2596 aa)
	APOB	Apolipoprotein B-100. (4566 aa)
	MSR1	Macrophage scavenger receptor types I and II isoform X1. (454 aa)
	APOLD1	Apolipoprotein L domain-containing protein 1. (248 aa)
	LOC111176714	Scavenger receptor cysteine-rich type 1 protein M130 isoform X1. (1115 aa)
	AMBP	Protein AMBP. (352 aa)
	APOE	Apolipoprotein E. (316 aa)
	LOC111179563	Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. (345 aa)
	IRGQ	Immunity-related GTPase family Q protein isoform X1. (621 aa)
	SSC5D	Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D. (1562 aa)
	SCGB3A2	Secretoglobin family 3A member 2. (128 aa)
	SSC4D	Scavenger receptor cysteine-rich domain-containing group B protein. (583 aa)
	SPARC	SPARC. (303 aa)
	MARCO	Macrophage receptor MARCO isoform X1. (410 aa)
	HBZ	Hemoglobin subunit zeta; Belongs to the globin family. (142 aa)
	CD6	T-cell differentiation antigen CD6 isoform X1. (675 aa)
	HBM	Hemoglobin subunit mu; Belongs to the globin family. (141 aa)
	HBQ1	Hemoglobin subunit theta-1-like; Belongs to the globin family. (142 aa)
	LOC111185089	Hemoglobin subunit alpha; Belongs to the globin family. (142 aa)
	SCARA5	Scavenger receptor class A member 5; Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non- transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the de [...] (495 aa)
	SCARF1	Scavenger receptor class F member 1 isoform X1. (870 aa)
	SCARB1	Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family. (511 aa)
	LOC111187813	Apolipoprotein L2-like. (268 aa)
	STAB2	Stabilin-2 isoform X1. (2663 aa)
	LOC111187870	Apolipoprotein L6-like. (341 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMBP	APOB	A0A2Y9NP53	A0A2Y9NAV4	Protein AMBP.	Apolipoprotein B-100.	0.446
AMBP	HPX	A0A2Y9NP53	A0A2Y9MCX1	Protein AMBP.	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.	0.798
AMBP	IGLL1	A0A2Y9NP53	A0A2Y9LBK7	Protein AMBP.	Immunoglobulin lambda-like polypeptide 1 isoform X1.	0.465
AMBP	LOC111179563	A0A2Y9NP53	A0A2Y9P6N1	Protein AMBP.	Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.	0.769
APOA1	APOB	A0A2Y9LZH5	A0A2Y9NAV4	Apolipoprotein A-I.	Apolipoprotein B-100.	0.788
APOA1	APOE	A0A2Y9LZH5	A0A2Y9P221	Apolipoprotein A-I.	Apolipoprotein E.	0.799
APOA1	LOC111163515	A0A2Y9LZH5	A0A2Y9LRN9	Apolipoprotein A-I.	Uncharacterized protein LOC111163515.	0.670
APOA1	LOC111179563	A0A2Y9LZH5	A0A2Y9P6N1	Apolipoprotein A-I.	Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.	0.402
APOB	AMBP	A0A2Y9NAV4	A0A2Y9NP53	Apolipoprotein B-100.	Protein AMBP.	0.446
APOB	APOA1	A0A2Y9NAV4	A0A2Y9LZH5	Apolipoprotein B-100.	Apolipoprotein A-I.	0.788
APOB	APOE	A0A2Y9NAV4	A0A2Y9P221	Apolipoprotein B-100.	Apolipoprotein E.	0.968
APOB	CALR	A0A2Y9NAV4	A0A2Y9MA80	Apolipoprotein B-100.	Calreticulin.	0.565
APOB	CALR3	A0A2Y9NAV4	A0A2Y9LYA2	Apolipoprotein B-100.	Calreticulin.	0.548
APOB	HBB	A0A2Y9NAV4	A0A140GN62	Apolipoprotein B-100.	Hemoglobin subunit beta; Belongs to the globin family.	0.532
APOB	HBM	A0A2Y9NAV4	A0A2Y9PWX6	Apolipoprotein B-100.	Hemoglobin subunit mu; Belongs to the globin family.	0.462
APOB	HBQ1	A0A2Y9NAV4	A0A2Y9PXD0	Apolipoprotein B-100.	Hemoglobin subunit theta-1-like; Belongs to the globin family.	0.445
APOB	HBZ	A0A2Y9NAV4	A0A2Y9PT12	Apolipoprotein B-100.	Hemoglobin subunit zeta; Belongs to the globin family.	0.462
APOB	LOC111164620	A0A2Y9NAV4	A0A2Y9LY02	Apolipoprotein B-100.	Platelet glycoprotein 4-like; Belongs to the CD36 family.	0.727
APOB	LOC111164621	A0A2Y9NAV4	A0A2Y9LSM4	Apolipoprotein B-100.	Platelet glycoprotein 4; Belongs to the CD36 family.	0.727
APOB	LOC111179563	A0A2Y9NAV4	A0A2Y9P6N1	Apolipoprotein B-100.	Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.	0.550