STRINGSTRING
IGF1 IGF1 IGF1R IGF1R IGF2 IGF2 GRB2 GRB2 SOS1 SOS1 SHC1 SHC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IGF1Insulin-like growth factor I isoform X1. (186 aa)
IGF1RTyrosine-protein kinase receptor. (1368 aa)
IGF2Insulin-like growth factor II isoform X3. (237 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
SOS1Son of sevenless homolog 1 isoform X1. (1333 aa)
SHC1SHC-transforming protein 1 isoform X1. (609 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.