STRINGSTRING
JUN JUN IGLL1 IGLL1 MAPK1 MAPK1 PSME2 PSME2 PSME1 PSME1 MAP3K7 MAP3K7 PSMB5 PSMB5 PSMC2 PSMC2 PSMA1 PSMA1 LOC111163081 LOC111163081 PSMB11 PSMB11 LOC111165935 LOC111165935 VAV1 VAV1 MAP2K7 MAP2K7 PSMD10 PSMD10 LOC111166275 LOC111166275 KXD1 KXD1 PSMD3 PSMD3 PIK3R2 PIK3R2 TAB2 TAB2 CCDC71L CCDC71L PSMB3 PSMB3 FCER1G FCER1G LOC111166997 LOC111166997 SHC1 SHC1 LYN LYN PSMB1 PSMB1 MAPK10 MAPK10 FCRL4 FCRL4 TAB3 TAB3 LOC111166421 LOC111166421 FCRL5 FCRL5 FCRL1 FCRL1 FCER1A FCER1A NFATC1 NFATC1 PSMD13 PSMD13 LOC111170125 LOC111170125 PSMB4 PSMB4 SYK SYK HRAS HRAS TEC TEC MAPK9 MAPK9 CARD11 CARD11 ERAS ERAS MAPK8 MAPK8 TXK TXK LOC111171742 LOC111171742 PSMD4 PSMD4 PSMD1 PSMD1 IKBKG IKBKG PAK2 PAK2 PSMD14 PSMD14 PSMC6 PSMC6 PSMA6 PSMA6 PSMA3 PSMA3 PIK3CA PIK3CA CLNK CLNK CHUK CHUK IKBKB IKBKB PSMD6 PSMD6 SOS1 SOS1 MAP3K20 MAP3K20 PSMC1 PSMC1 NFKBIA NFKBIA PPP3R2 PPP3R2 PSMD9 PSMD9 PSMA7 PSMA7 NFATC2 NFATC2 WDR92 WDR92 PPP3R1 PPP3R1 PSME4 PSME4 PIK3R1 PIK3R1 PSMB6 PSMB6 PSMD11 PSMD11 LCP2 LCP2 MAP3K1 MAP3K1 FBXW11 FBXW11 PDPK1 PDPK1 LOC111186270 LOC111186270 GAB2 GAB2 RPS27A RPS27A TAB1 TAB1 LOC111186271 LOC111186271 PSMA2 PSMA2 LOC111184480 LOC111184480 PSMF1 PSMF1 MAP2K4 MAP2K4 PAK1 PAK1 LOC111184052 LOC111184052 MS4A2 MS4A2 HARBI1 HARBI1 PSMD12 PSMD12 PSMC3 PSMC3 RELA RELA LOC111183908 LOC111183908 LAT LAT PPP3CB PPP3CB PLCG1 PLCG1 SPNS1 SPNS1 RAC1 RAC1 LAT2 LAT2 GRB2 GRB2 ITK ITK PSMC5 PSMC5 MAPK3 MAPK3 PSMA8 PSMA8 NRAS NRAS TRAF6 TRAF6 MALT1 MALT1 NFATC3 NFATC3 PSMD8 PSMD8 PPP3CA PPP3CA PSMB10 PSMB10 PSMB8 PSMB8 NFKB1 NFKB1 VAV3 VAV3 BCL10 BCL10 PSMC4 PSMC4 PSMA4 PSMA4 NFAT5 NFAT5 CSDE1 CSDE1 PIK3CB PIK3CB PSMA5 PSMA5 PLCG2 PLCG2 PSMD7 PSMD7 PSMB7 PSMB7 PRKCQ PRKCQ CALM1 CALM1 BTK BTK PSMB9 PSMB9 PSMD5 PSMD5 FOSL2 FOSL2 FOS FOS VAV2 VAV2 KRAS KRAS PSMB2 PSMB2 LOC111174455 LOC111174455
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
JUNTranscription factor AP-1; Belongs to the bZIP family. (343 aa)
IGLL1Immunoglobulin lambda-like polypeptide 1 isoform X1. (212 aa)
MAPK1Mitogen-activated protein kinase. (380 aa)
PSME2Proteasome activator complex subunit 2. (239 aa)
PSME1Proteasome activator complex subunit 1. (249 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMC226S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
LOC111163081LOW QUALITY PROTEIN: immunoglobulin lambda-1 light chain-like. (235 aa)
PSMB11Proteasome subunit beta. (291 aa)
LOC111165935Ras-like protein isoform X1. (285 aa)
VAV1Proto-oncogene vav isoform X1. (845 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (458 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
LOC111166275Proteasome activator complex subunit 3-like. (165 aa)
KXD1kxDL motif-containing protein 1 isoform X1. (196 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (534 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
TAB2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1. (693 aa)
CCDC71LCoiled-coil domain-containing protein 71L. (237 aa)
PSMB3Proteasome subunit beta. (205 aa)
FCER1GHigh affinity immunoglobulin epsilon receptor subunit gamma. (86 aa)
LOC111166997Fc receptor-like protein 3 isoform X2. (726 aa)
SHC1SHC-transforming protein 1 isoform X1. (609 aa)
LYNTyrosine-protein kinase. (518 aa)
PSMB1Proteasome subunit beta. (241 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
FCRL4Fc receptor-like protein 4 isoform X1. (533 aa)
TAB3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3. (717 aa)
LOC111166421Proteasome activator complex subunit 3. (254 aa)
FCRL5Fc receptor-like protein 5 isoform X1. (848 aa)
FCRL1LOW QUALITY PROTEIN: Fc receptor-like protein 1. (398 aa)
FCER1AHigh affinity immunoglobulin epsilon receptor subunit alpha isoform X1. (258 aa)
NFATC1Nuclear factor of activated T-cells, cytoplasmic 1 isoform X1. (928 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
LOC111170125Myosin light chain 1, skeletal muscle isoform-like isoform X1; Belongs to the calmodulin family. (304 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa)
SYKTyrosine-protein kinase. (626 aa)
HRASGTPase HRas isoform X1. (189 aa)
TECTyrosine-protein kinase. (658 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
CARD11Caspase recruitment domain-containing protein 11 isoform X1. (1154 aa)
ERASGTPase ERas. (233 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
TXKTyrosine-protein kinase. (550 aa)
LOC111171742Ubiquitin-conjugating enzyme E2 variant 1. (147 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform X1. (380 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (954 aa)
IKBKGNF-kappa-B essential modulator isoform X1. (412 aa)
PAK2Non-specific serine/threonine protein kinase. (523 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14 isoform X1. (310 aa)
PSMC626S proteasome regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CLNKCytokine-dependent hematopoietic cell linker isoform X1. (452 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (882 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6 isoform X1. (452 aa)
SOS1Son of sevenless homolog 1 isoform X1. (1333 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20 isoform X1. (800 aa)
PSMC126S proteasome regulatory subunit 4 isoform X1; Belongs to the AAA ATPase family. (440 aa)
NFKBIANF-kappa-B inhibitor alpha. (314 aa)
PPP3R2LOW QUALITY PROTEIN: calcineurin subunit B type 2. (231 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9 isoform X1. (223 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
NFATC2Nuclear factor of activated T-cells, cytoplasmic 2 isoform X1. (943 aa)
WDR92WD repeat-containing protein 92. (357 aa)
PPP3R1Calcineurin subunit B type 1. (170 aa)
PSME4LOW QUALITY PROTEIN: proteasome activator complex subunit 4. (1845 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
PSMB6Proteasome subunit beta. (239 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (422 aa)
LCP2Lymphocyte cytosolic protein 2 isoform X1. (534 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1 isoform X1. (1508 aa)
FBXW11F-box/WD repeat-containing protein 11 isoform X1. (563 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
LOC111186270GRB2-related adapter protein 2 isoform X1. (337 aa)
GAB2GRB2-associated-binding protein 2 isoform X1. (678 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
TAB1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1. (504 aa)
LOC111186271GRB2-related adapter protein 2-like isoform X1. (105 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
LOC111184480TCR gamma alternate reading frame protein. (343 aa)
PSMF1Proteasome inhibitor PI31 subunit isoform X1. (270 aa)
MAP2K4Dual specificity mitogen-activated protein kinase kinase 4 isoform X4; Belongs to the protein kinase superfamily. (410 aa)
PAK1Non-specific serine/threonine protein kinase. (543 aa)
LOC111184052LOW QUALITY PROTEIN: membrane-spanning 4-domains subfamily A member 12-like. (263 aa)
MS4A2High affinity immunoglobulin epsilon receptor subunit beta. (243 aa)
HARBI1Putative nuclease HARBI1. (349 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12. (456 aa)
PSMC326S proteasome regulatory subunit 6A isoform X1; Belongs to the AAA ATPase family. (423 aa)
RELATranscription factor p65 isoform X1. (562 aa)
LOC111183908B-lymphocyte antigen CD20-like. (303 aa)
LATLinker for activation of T-cells family member 1 isoform X1. (270 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
SPNS1Protein spinster homolog 1 isoform X1. (606 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (192 aa)
LAT2Linker for activation of T-cells family member 2 isoform X1. (225 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
ITKTyrosine-protein kinase. (620 aa)
PSMC526S proteasome regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa)
PSMA8Proteasome subunit alpha type. (269 aa)
NRASGTPase NRas. (189 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa)
MALT1Mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X1. (850 aa)
NFATC3Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1073 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (351 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMB8Proteasome subunit beta. (276 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa)
VAV3Guanine nucleotide exchange factor VAV3. (954 aa)
BCL10B-cell lymphoma/leukemia 10. (233 aa)
PSMC426S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
NFAT5Nuclear factor of activated T-cells 5 isoform X1. (1553 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (322 aa)
PSMB7Proteasome subunit beta. (277 aa)
PRKCQProtein kinase C. (665 aa)
CALM1Calmodulin-1; Belongs to the calmodulin family. (149 aa)
BTKTyrosine-protein kinase. (687 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5. (504 aa)
FOSL2Fos-related antigen 2 isoform X1. (327 aa)
FOSProto-oncogene c-Fos. (380 aa)
VAV2Guanine nucleotide exchange factor VAV2 isoform X1. (879 aa)
KRASGTPase KRas. (188 aa)
PSMB2Proteasome subunit beta. (201 aa)
LOC111174455LOW QUALITY PROTEIN: death domain-containing membrane protein NRADD-like. (248 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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