STRINGSTRING
RPS6KA5 RPS6KA5 NCAM2 NCAM2 SOS1 SOS1 CACNA1I CACNA1I CNTN2 CNTN2 PTPRA PTPRA SPTBN4 SPTBN4 PTK2 PTK2 NCAN NCAN KRAS KRAS SPTAN1 SPTAN1 CSDE1 CSDE1 CREB1 CREB1 PTPRE PTPRE ERAS ERAS HRAS HRAS RPS6KA4 RPS6KA4 SPTBN2 SPTBN2 FYN FYN LOC111165935 LOC111165935 GRB2 GRB2 NCAM1 NCAM1 MAPK3 MAPK3 SPTA1 SPTA1 MAPK1 MAPK1 NRAS NRAS SPTB SPTB SPTBN1 SPTBN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPS6KA5Ribosomal protein S6 kinase. (800 aa)
NCAM2Neural cell adhesion molecule 2 isoform X1. (837 aa)
SOS1Son of sevenless homolog 1 isoform X1. (1333 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2193 aa)
CNTN2Contactin-2. (1043 aa)
PTPRAReceptor-type tyrosine-protein phosphatase alpha. (802 aa)
SPTBN4Spectrin beta chain; Belongs to the spectrin family. (2560 aa)
PTK2Focal adhesion kinase 1 isoform X22; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1116 aa)
NCANNeurocan core protein isoform X1. (1360 aa)
KRASGTPase KRas. (188 aa)
SPTAN1Spectrin alpha chain, non-erythrocytic 1 isoform X1. (2477 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
PTPREReceptor-type tyrosine-protein phosphatase epsilon isoform X3. (717 aa)
ERASGTPase ERas. (233 aa)
HRASGTPase HRas isoform X1. (189 aa)
RPS6KA4Ribosomal protein S6 kinase. (771 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2397 aa)
FYNTyrosine-protein kinase. (537 aa)
LOC111165935Ras-like protein isoform X1. (285 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
NCAM1Neural cell adhesion molecule 1 isoform X1. (1147 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa)
SPTA1Spectrin alpha chain, erythrocytic 1 isoform X1. (2417 aa)
MAPK1Mitogen-activated protein kinase. (380 aa)
NRASGTPase NRas. (189 aa)
SPTBSpectrin beta chain; Belongs to the spectrin family. (2330 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2363 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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