STRINGSTRING
PPP4R1 PPP4R1 CDC42 CDC42 FYN FYN VAV1 VAV1 PIK3R2 PIK3R2 CD3D CD3D CD3G CD3G CD3E CD3E LYN LYN PAK3 PAK3 PPP2R1B PPP2R1B LOC111169445 LOC111169445 THEM4 THEM4 CD247 CD247 CD80 CD80 MAP3K14 MAP3K14 CD86 CD86 LOC111171396 LOC111171396 ICOS ICOS CD28 CD28 PDCD1 PDCD1 PAK2 PAK2 CTLA4 CTLA4 PPP2CB PPP2CB FNDC3B FNDC3B PIK3CA PIK3CA PPP2R5E PPP2R5E CD274 CD274 PPP2R5C PPP2R5C PIK3R3 PIK3R3 FNDC3A FNDC3A PDCD1LG2 PDCD1LG2 PTPN6 PTPN6 MAP3K8 MAP3K8 LCK LCK CSK CSK PPP4R4 PPP4R4 LOC111178928 LOC111178928 LOC111178931 LOC111178931 LOC111178925 LOC111178925 LOC111178929 LOC111178929 PPP2R5D PPP2R5D CD276 CD276 KIAA1468 KIAA1468 LOC111178927 LOC111178927 PPP2R1A PPP2R1A YES1 YES1 PPP2CA PPP2CA GRB2 GRB2 PPP2R5B PPP2R5B RAC1 RAC1 FNBP4 FNBP4 PPP2R5A PPP2R5A SRC SRC PAK1 PAK1 LOC111186264 LOC111186264 LOC111186271 LOC111186271 ANKRD60 ANKRD60 PRR5 PRR5 LOC111186270 LOC111186270 PDPK1 PDPK1 PIK3R1 PIK3R1 PTPN11 PTPN11 LOC111187198 LOC111187198 RICTOR RICTOR CD4 CD4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP4R1Serine/threonine-protein phosphatase 4 regulatory subunit 1 isoform X1. (939 aa)
CDC42Cell division control protein 42 homolog isoform X2. (191 aa)
FYNTyrosine-protein kinase. (537 aa)
VAV1Proto-oncogene vav isoform X1. (845 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
CD3DT-cell surface glycoprotein CD3 delta chain. (171 aa)
CD3GT-cell surface glycoprotein CD3 gamma chain. (178 aa)
CD3ET-cell surface glycoprotein CD3 epsilon chain. (197 aa)
LYNTyrosine-protein kinase. (518 aa)
PAK3Non-specific serine/threonine protein kinase. (559 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (601 aa)
LOC111169445Acyl-coenzyme A thioesterase THEM4-like. (174 aa)
THEM4Acyl-coenzyme A thioesterase THEM4. (224 aa)
CD247T-cell surface glycoprotein CD3 zeta chain isoform X1. (185 aa)
CD80T-lymphocyte activation antigen CD80 isoform X1. (295 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14 isoform X1. (961 aa)
CD86T-lymphocyte activation antigen CD86 isoform X1. (344 aa)
LOC111171396CD276 antigen-like. (120 aa)
ICOSInducible T-cell costimulator isoform X1. (227 aa)
CD28T-cell-specific surface glycoprotein CD28. (265 aa)
PDCD1Programmed cell death protein 1 isoform X1. (288 aa)
PAK2Non-specific serine/threonine protein kinase. (523 aa)
CTLA4Cytotoxic T-lymphocyte protein 4 isoform X1. (223 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
FNDC3BFibronectin type III domain-containing protein 3B isoform X1. (1215 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
CD274Programmed cell death 1 ligand 1 isoform X2. (312 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (578 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa)
FNDC3AFibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
PDCD1LG2Programmed cell death 1 ligand 2 isoform X1. (337 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (468 aa)
LCKTyrosine-protein kinase. (509 aa)
CSKTyrosine-protein kinase. (528 aa)
PPP4R4Serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform X1. (872 aa)
LOC111178928DLA class II histocompatibility antigen, DR-1 beta chain-like. (266 aa)
LOC111178931HLA class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. (253 aa)
LOC111178925boLa class II histocompatibility antigen, DQB*0101 beta chain-like isoform X2. (276 aa)
LOC111178929HLA class II histocompatibility antigen, DRB1-4 beta chain-like isoform X1. (231 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
CD276CD276 antigen. (275 aa)
KIAA1468lisH domain and HEAT repeat-containing protein KIAA1468 homolog isoform X2. (1214 aa)
LOC111178927HLA class II histocompatibility antigen, DQ alpha 2 chain; Belongs to the MHC class II family. (255 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa)
YES1Tyrosine-protein kinase. (541 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (192 aa)
FNBP4Formin-binding protein 4. (1013 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (487 aa)
SRCTyrosine-protein kinase. (562 aa)
PAK1Non-specific serine/threonine protein kinase. (543 aa)
LOC111186264ICOS ligand-like isoform X1. (580 aa)
LOC111186271GRB2-related adapter protein 2-like isoform X1. (105 aa)
ANKRD60LOW QUALITY PROTEIN: ankyrin repeat domain-containing protein 60. (677 aa)
PRR5Proline-rich protein 5 isoform X1. (389 aa)
LOC111186270GRB2-related adapter protein 2 isoform X1. (337 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
LOC111187198Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (617 aa)
RICTORRapamycin-insensitive companion of mTOR isoform X1. (1732 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (455 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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