18 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	PDPK1	3-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
	THEM4	Acyl-coenzyme A thioesterase THEM4. (224 aa)
	CD80	T-lymphocyte activation antigen CD80 isoform X1. (295 aa)
	MAP3K14	Mitogen-activated protein kinase kinase kinase 14 isoform X1. (961 aa)
	CD86	T-lymphocyte activation antigen CD86 isoform X1. (344 aa)
	LOC111171396	CD276 antigen-like. (120 aa)
	CD28	T-cell-specific surface glycoprotein CD28. (265 aa)
	PRR5	Proline-rich protein 5 isoform X1. (389 aa)
	CD276	CD276 antigen. (275 aa)
	LCK	Tyrosine-protein kinase. (509 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	MAP3K8	Mitogen-activated protein kinase kinase kinase 8. (468 aa)
	PIK3R3	Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	PIK3R2	Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
	LOC111169445	Acyl-coenzyme A thioesterase THEM4-like. (174 aa)
	RICTOR	Rapamycin-insensitive companion of mTOR isoform X1. (1732 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD28	CD80	A0A2Y9MQH7	A0A2Y9MFX2	T-cell-specific surface glycoprotein CD28.	T-lymphocyte activation antigen CD80 isoform X1.	0.988
CD28	CD86	A0A2Y9MQH7	A0A2Y9MK30	T-cell-specific surface glycoprotein CD28.	T-lymphocyte activation antigen CD86 isoform X1.	0.985
CD28	LCK	A0A2Y9MQH7	A0A2Y9NNB7	T-cell-specific surface glycoprotein CD28.	Tyrosine-protein kinase.	0.567
CD28	PIK3CA	A0A2Y9MQH7	A0A2Y9MZW2	T-cell-specific surface glycoprotein CD28.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.921
CD28	PIK3R1	A0A2Y9MQH7	A0A2Y9Q8T5	T-cell-specific surface glycoprotein CD28.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.927
CD28	PIK3R2	A0A2Y9MQH7	A0A2Y9LXY5	T-cell-specific surface glycoprotein CD28.	Phosphatidylinositol 3-kinase regulatory subunit beta.	0.924
CD28	PIK3R3	A0A2Y9MQH7	A0A2Y9NAQ0	T-cell-specific surface glycoprotein CD28.	Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1.	0.924
CD80	CD28	A0A2Y9MFX2	A0A2Y9MQH7	T-lymphocyte activation antigen CD80 isoform X1.	T-cell-specific surface glycoprotein CD28.	0.988
CD80	CD86	A0A2Y9MFX2	A0A2Y9MK30	T-lymphocyte activation antigen CD80 isoform X1.	T-lymphocyte activation antigen CD86 isoform X1.	0.998
CD80	FYN	A0A2Y9MFX2	A0A2Y9LLH3	T-lymphocyte activation antigen CD80 isoform X1.	Tyrosine-protein kinase.	0.463
CD80	LCK	A0A2Y9MFX2	A0A2Y9NNB7	T-lymphocyte activation antigen CD80 isoform X1.	Tyrosine-protein kinase.	0.523
CD80	PIK3CA	A0A2Y9MFX2	A0A2Y9MZW2	T-lymphocyte activation antigen CD80 isoform X1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.529
CD80	PIK3R1	A0A2Y9MFX2	A0A2Y9Q8T5	T-lymphocyte activation antigen CD80 isoform X1.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.505
CD80	PIK3R2	A0A2Y9MFX2	A0A2Y9LXY5	T-lymphocyte activation antigen CD80 isoform X1.	Phosphatidylinositol 3-kinase regulatory subunit beta.	0.505
CD80	PIK3R3	A0A2Y9MFX2	A0A2Y9NAQ0	T-lymphocyte activation antigen CD80 isoform X1.	Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1.	0.505
CD86	CD28	A0A2Y9MK30	A0A2Y9MQH7	T-lymphocyte activation antigen CD86 isoform X1.	T-cell-specific surface glycoprotein CD28.	0.985
CD86	CD80	A0A2Y9MK30	A0A2Y9MFX2	T-lymphocyte activation antigen CD86 isoform X1.	T-lymphocyte activation antigen CD80 isoform X1.	0.998
CD86	FYN	A0A2Y9MK30	A0A2Y9LLH3	T-lymphocyte activation antigen CD86 isoform X1.	Tyrosine-protein kinase.	0.498
CD86	LCK	A0A2Y9MK30	A0A2Y9NNB7	T-lymphocyte activation antigen CD86 isoform X1.	Tyrosine-protein kinase.	0.502
CD86	PIK3CA	A0A2Y9MK30	A0A2Y9MZW2	T-lymphocyte activation antigen CD86 isoform X1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.500