14 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CD86	T-lymphocyte activation antigen CD86 isoform X1. (344 aa)
	PAK1	Non-specific serine/threonine protein kinase. (543 aa)
	RAC1	Ras-related C3 botulinum toxin substrate 1. (192 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	CD276	CD276 antigen. (275 aa)
	LCK	Tyrosine-protein kinase. (509 aa)
	PAK2	Non-specific serine/threonine protein kinase. (523 aa)
	CD28	T-cell-specific surface glycoprotein CD28. (265 aa)
	LOC111171396	CD276 antigen-like. (120 aa)
	CD80	T-lymphocyte activation antigen CD80 isoform X1. (295 aa)
	PAK3	Non-specific serine/threonine protein kinase. (559 aa)
	VAV1	Proto-oncogene vav isoform X1. (845 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	CDC42	Cell division control protein 42 homolog isoform X2. (191 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD28	CD80	A0A2Y9MQH7	A0A2Y9MFX2	T-cell-specific surface glycoprotein CD28.	T-lymphocyte activation antigen CD80 isoform X1.	0.988
CD28	CD86	A0A2Y9MQH7	A0A2Y9MK30	T-cell-specific surface glycoprotein CD28.	T-lymphocyte activation antigen CD86 isoform X1.	0.985
CD28	GRB2	A0A2Y9MQH7	A0A2Y9PJ90	T-cell-specific surface glycoprotein CD28.	Growth factor receptor-bound protein 2.	0.937
CD28	LCK	A0A2Y9MQH7	A0A2Y9NNB7	T-cell-specific surface glycoprotein CD28.	Tyrosine-protein kinase.	0.567
CD80	CD28	A0A2Y9MFX2	A0A2Y9MQH7	T-lymphocyte activation antigen CD80 isoform X1.	T-cell-specific surface glycoprotein CD28.	0.988
CD80	CD86	A0A2Y9MFX2	A0A2Y9MK30	T-lymphocyte activation antigen CD80 isoform X1.	T-lymphocyte activation antigen CD86 isoform X1.	0.998
CD80	CDC42	A0A2Y9MFX2	A0A2Y9LCK9	T-lymphocyte activation antigen CD80 isoform X1.	Cell division control protein 42 homolog isoform X2.	0.557
CD80	FYN	A0A2Y9MFX2	A0A2Y9LLH3	T-lymphocyte activation antigen CD80 isoform X1.	Tyrosine-protein kinase.	0.463
CD80	GRB2	A0A2Y9MFX2	A0A2Y9PJ90	T-lymphocyte activation antigen CD80 isoform X1.	Growth factor receptor-bound protein 2.	0.566
CD80	LCK	A0A2Y9MFX2	A0A2Y9NNB7	T-lymphocyte activation antigen CD80 isoform X1.	Tyrosine-protein kinase.	0.523
CD80	RAC1	A0A2Y9MFX2	A0A2Y9PL77	T-lymphocyte activation antigen CD80 isoform X1.	Ras-related C3 botulinum toxin substrate 1.	0.423
CD80	VAV1	A0A2Y9MFX2	A0A2Y9LSY4	T-lymphocyte activation antigen CD80 isoform X1.	Proto-oncogene vav isoform X1.	0.523
CD86	CD28	A0A2Y9MK30	A0A2Y9MQH7	T-lymphocyte activation antigen CD86 isoform X1.	T-cell-specific surface glycoprotein CD28.	0.985
CD86	CD80	A0A2Y9MK30	A0A2Y9MFX2	T-lymphocyte activation antigen CD86 isoform X1.	T-lymphocyte activation antigen CD80 isoform X1.	0.998
CD86	CDC42	A0A2Y9MK30	A0A2Y9LCK9	T-lymphocyte activation antigen CD86 isoform X1.	Cell division control protein 42 homolog isoform X2.	0.585
CD86	FYN	A0A2Y9MK30	A0A2Y9LLH3	T-lymphocyte activation antigen CD86 isoform X1.	Tyrosine-protein kinase.	0.498
CD86	GRB2	A0A2Y9MK30	A0A2Y9PJ90	T-lymphocyte activation antigen CD86 isoform X1.	Growth factor receptor-bound protein 2.	0.572
CD86	LCK	A0A2Y9MK30	A0A2Y9NNB7	T-lymphocyte activation antigen CD86 isoform X1.	Tyrosine-protein kinase.	0.502
CD86	VAV1	A0A2Y9MK30	A0A2Y9LSY4	T-lymphocyte activation antigen CD86 isoform X1.	Proto-oncogene vav isoform X1.	0.573
CDC42	CD80	A0A2Y9LCK9	A0A2Y9MFX2	Cell division control protein 42 homolog isoform X2.	T-lymphocyte activation antigen CD80 isoform X1.	0.557