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PAFAH2 PAFAH2 LOC111187198 LOC111187198 GNB1 GNB1 PTPN11 PTPN11 NOS1 NOS1 ATP2A2 ATP2A2 PRKG2 PRKG2 TRPC3 TRPC3 ORAI1 ORAI1 P2RX4 P2RX4 P2RX2 P2RX2 P2RX7 P2RX7 LOC111185989 LOC111185989 ATP2A3 ATP2A3 PLA2G4A PLA2G4A PDE5A PDE5A P2RX1 P2RX1 P2RX3 P2RX3 GNG3 GNG3 ATP2B4 ATP2B4 GNG13 GNG13 PDE2A PDE2A PPP2R5A PPP2R5A REEP2 REEP2 PECAM1 PECAM1 ATP2A1 ATP2A1 TRPC7 TRPC7 ORAI2 ORAI2 ORAI3 ORAI3 PPP2R5B PPP2R5B MILR1 MILR1 PPP2CA PPP2CA LOC111182630 LOC111182630 GNGT1 GNGT1 GNG8 GNG8 GNB2 GNB2 SLC8A2 SLC8A2 SRI SRI PPP2R1A PPP2R1A PTGIR PTGIR GNG11 GNG11 GNG12 GNG12 GNG5 GNG5 ITPR3 ITPR3 PPP2R5D PPP2R5D LOC111177332 LOC111177332 CALM1 CALM1 MAPK14 MAPK14 GNB5 GNB5 LRP8 LRP8 LOC111176690 LOC111176690 SLC8A1 SLC8A1 PTPN6 PTPN6 GNB3 GNB3 ITPR2 ITPR2 NOS3 NOS3 APOB APOB GNG2 GNG2 PPP2R5C PPP2R5C PDE1B PDE1B PRKG1 PRKG1 PPP2R5E PPP2R5E GNB4 GNB4 ITPR1 ITPR1 PPP2CB PPP2CB ATP2B3 ATP2B3 SLC8A3 SLC8A3 PDE11A PDE11A GNG7 GNG7 PDE1A PDE1A LOC111170557 LOC111170557 REEP3 REEP3 LOC111170125 LOC111170125 TRPC6 TRPC6 REEP4 REEP4 ATP2B2 ATP2B2 PPP2R1B PPP2R1B PDE10A PDE10A MRVI1 MRVI1 LOC111163515 LOC111163515 P2RX6 P2RX6 PDE9A PDE9A ATP2B1 ATP2B1 GNG4 GNG4 FGR FGR GNGT2 GNGT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PAFAH2Platelet-activating factor acetylhydrolase. (392 aa)
LOC111187198Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (617 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
NOS1Nitric oxide synthase, brain isoform X1. (1461 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
PRKG2cGMP-dependent protein kinase. (792 aa)
TRPC3LOW QUALITY PROTEIN: short transient receptor potential channel 3; Belongs to the transient receptor (TC 1.A.4) family. (920 aa)
ORAI1Calcium release-activated calcium channel protein 1. (410 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (388 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (479 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
LOC111185989Nitric oxide synthase; Produces nitric oxide (NO). (1146 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1057 aa)
PLA2G4APhospholipase A2. (749 aa)
PDE5APhosphodiesterase. (865 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
PDE2APhosphodiesterase. (971 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (487 aa)
REEP2Receptor expression-enhancing protein. (254 aa)
PECAM1Platelet endothelial cell adhesion molecule isoform X1. (701 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1006 aa)
TRPC7Short transient receptor potential channel 7 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
ORAI2Protein orai-2. (254 aa)
ORAI3Protein orai-3. (306 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
MILR1Allergin-1 isoform X1. (318 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
LOC111182630Platelet endothelial cell adhesion molecule-like isoform X2. (305 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
SLC8A2Sodium/calcium exchanger 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (922 aa)
SRISorcin. (198 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa)
PTGIRProstacyclin receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3 isoform X1. (2671 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
LOC111177332Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CALM1Calmodulin-1; Belongs to the calmodulin family. (149 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5 isoform X1. (414 aa)
LRP8Low-density lipoprotein receptor-related protein 8 isoform X1. (996 aa)
LOC111176690Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1. (340 aa)
SLC8A1Sodium/calcium exchanger 1 isoform X7; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (1004 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X2. (299 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
APOBApolipoprotein B-100. (4566 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (578 aa)
PDE1BPhosphodiesterase. (542 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4 isoform X1. (340 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2749 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1248 aa)
SLC8A3Sodium/calcium exchanger 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (920 aa)
PDE11APhosphodiesterase. (930 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PDE1APhosphodiesterase. (536 aa)
LOC111170557LOW QUALITY PROTEIN: short transient receptor potential channel 2-like; Belongs to the transient receptor (TC 1.A.4) family. (902 aa)
REEP3Receptor expression-enhancing protein. (258 aa)
LOC111170125Myosin light chain 1, skeletal muscle isoform-like isoform X1; Belongs to the calmodulin family. (304 aa)
TRPC6Short transient receptor potential channel 6 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (932 aa)
REEP4Receptor expression-enhancing protein. (257 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1320 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (601 aa)
PDE10APhosphodiesterase. (943 aa)
MRVI1Protein MRVI1 isoform X1. (902 aa)
LOC111163515Uncharacterized protein LOC111163515. (1806 aa)
P2RX6P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (393 aa)
PDE9APhosphodiesterase. (529 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
FGRTyrosine-protein kinase. (526 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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