STRINGSTRING
CSF2 CSF2 GRB2 GRB2 IL5 IL5 CSF2RB CSF2RB GAB2 GAB2 IL9R IL9R IL2RB IL2RB PTK2B PTK2B LGALS9 LGALS9 PIK3R2 PIK3R2 STAT3 STAT3 LOC111166483 LOC111166483 STAT5A STAT5A LOC111166741 LOC111166741 IL2 IL2 IL15 IL15 PIK3CD PIK3CD IL21 IL21 PIK3R1 PIK3R1 SHC1 SHC1 JAK3 JAK3 CSF2RA CSF2RA SASH3 SASH3 SYK SYK IL2RG IL2RG IL3RA IL3RA STAT1 STAT1 INPPL1 INPPL1 INPP5D INPP5D SOS2 SOS2 PIK3CA PIK3CA STAT4 STAT4 JAK2 JAK2 IL5RA IL5RA SOS1 SOS1 PIK3R3 PIK3R3 LOC111176455 LOC111176455 SAMSN1 SAMSN1 PTPN6 PTPN6 LCK LCK PIK3CB PIK3CB IL2RA IL2RA JAK1 JAK1 IL21R IL21R IL9 IL9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CSF2Granulocyte-macrophage colony-stimulating factor. (144 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (135 aa)
CSF2RBCytokine receptor common subunit beta. (902 aa)
GAB2GRB2-associated-binding protein 2 isoform X1. (678 aa)
IL9RInterleukin-9 receptor. (469 aa)
IL2RBInterleukin-2 receptor subunit beta isoform X1. (595 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1015 aa)
LGALS9Galectin. (356 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
LOC111166483Signal transducer and activator of transcription. (787 aa)
STAT5ASignal transducer and activator of transcription. (818 aa)
LOC111166741SAM and SH3 domain-containing protein 1 isoform X1. (1513 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (154 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (180 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (919 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (146 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
SHC1SHC-transforming protein 1 isoform X1. (609 aa)
JAK3Tyrosine-protein kinase. (1104 aa)
CSF2RAGranulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform X1. (430 aa)
SASH3SAM and SH3 domain-containing protein 3. (380 aa)
SYKTyrosine-protein kinase. (626 aa)
IL2RGCytokine receptor common subunit gamma isoform X1. (381 aa)
IL3RAInterleukin-3 receptor subunit alpha isoform X1. (473 aa)
STAT1Signal transducer and activator of transcription. (749 aa)
INPPL1Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1. (1264 aa)
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1150 aa)
SOS2Son of sevenless homolog 2 isoform X1. (1332 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
STAT4Signal transducer and activator of transcription. (748 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
IL5RAInterleukin-5 receptor subunit alpha isoform X1. (417 aa)
SOS1Son of sevenless homolog 1 isoform X1. (1333 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa)
LOC111176455Uncharacterized protein. (206 aa)
SAMSN1SAM domain-containing protein SAMSN-1. (373 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
LCKTyrosine-protein kinase. (509 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
IL2RAInterleukin-2 receptor subunit alpha. (275 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
IL21RInterleukin-21 receptor isoform X2. (560 aa)
IL9Interleukin-9. (141 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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