STRINGSTRING
IL2RA IL2RA IL2 IL2 PIK3CD PIK3CD LOC111187198 LOC111187198 PTPN11 PTPN11 PIK3R1 PIK3R1 IL2RB IL2RB GAB2 GAB2 RPS27A RPS27A CSF2RB CSF2RB CRK CRK HCK HCK LOC111184310 LOC111184310 IL5 IL5 GRB2 GRB2 CSF2 CSF2 YES1 YES1 YWHAZ YWHAZ JAK1 JAK1 PIK3CB PIK3CB PTPN6 PTPN6 RAPGEF1 RAPGEF1 PIK3R3 PIK3R3 SOS1 SOS1 IL5RA IL5RA JAK2 JAK2 PIK3CA PIK3CA INPP5D INPP5D INPPL1 INPPL1 IL3RA IL3RA IL2RG IL2RG TEC TEC SYK SYK CSF2RA CSF2RA JAK3 JAK3 CBL CBL LYN LYN PRKACA PRKACA SHC1 SHC1 PIK3R2 PIK3R2 LOC111166483 LOC111166483 STAT5A STAT5A VAV1 VAV1 FYN FYN CRKL CRKL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL2RAInterleukin-2 receptor subunit alpha. (275 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (154 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (919 aa)
LOC111187198Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (617 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
IL2RBInterleukin-2 receptor subunit beta isoform X1. (595 aa)
GAB2GRB2-associated-binding protein 2 isoform X1. (678 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
CSF2RBCytokine receptor common subunit beta. (902 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
HCKTyrosine-protein kinase. (506 aa)
LOC111184310Tyrosine-protein kinase. (369 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (135 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
CSF2Granulocyte-macrophage colony-stimulating factor. (144 aa)
YES1Tyrosine-protein kinase. (541 aa)
YWHAZ14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (245 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1 isoform X1. (1259 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa)
SOS1Son of sevenless homolog 1 isoform X1. (1333 aa)
IL5RAInterleukin-5 receptor subunit alpha isoform X1. (417 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1150 aa)
INPPL1Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1. (1264 aa)
IL3RAInterleukin-3 receptor subunit alpha isoform X1. (473 aa)
IL2RGCytokine receptor common subunit gamma isoform X1. (381 aa)
TECTyrosine-protein kinase. (658 aa)
SYKTyrosine-protein kinase. (626 aa)
CSF2RAGranulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform X1. (430 aa)
JAK3Tyrosine-protein kinase. (1104 aa)
CBLE3 ubiquitin-protein ligase CBL isoform X1. (910 aa)
LYNTyrosine-protein kinase. (518 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
SHC1SHC-transforming protein 1 isoform X1. (609 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
LOC111166483Signal transducer and activator of transcription. (787 aa)
STAT5ASignal transducer and activator of transcription. (818 aa)
VAV1Proto-oncogene vav isoform X1. (845 aa)
FYNTyrosine-protein kinase. (537 aa)
CRKLCrk-like protein. (303 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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