19 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KDR	Vascular endothelial growth factor receptor 2 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
	FNDC3B	Fibronectin type III domain-containing protein 3B isoform X1. (1215 aa)
	PRKCD	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (733 aa)
	ERAS	GTPase ERas. (233 aa)
	HRAS	GTPase HRas isoform X1. (189 aa)
	LOC111165935	Ras-like protein isoform X1. (285 aa)
	FNDC3A	Fibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
	KRAS	GTPase KRas. (188 aa)
	VEGFA	Vascular endothelial growth factor A isoform X1; Belongs to the PDGF/VEGF growth factor family. (214 aa)
	CSDE1	Cold shock domain-containing protein E1 isoform X1. (798 aa)
	NRAS	GTPase NRas. (189 aa)
	PRKCB	Protein kinase C. (689 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (670 aa)
	SPHK1	Sphingosine kinase 1 isoform X2. (484 aa)
	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
	RASA1	Ras GTPase-activating protein 1 isoform X1. (1040 aa)
	SRC	Tyrosine-protein kinase. (562 aa)
	PDPK1	3-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
	PRKCZ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (629 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	PDPK1	A0A2Y9P0H2	A0A2Y9Q4F2	Cold shock domain-containing protein E1 isoform X1.	3-phosphoinositide-dependent protein kinase 1 isoform X1.	0.429
CSDE1	PRKCD	A0A2Y9P0H2	A0A2Y9NAV7	Cold shock domain-containing protein E1 isoform X1.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.445
CSDE1	RASA1	A0A2Y9P0H2	A0A2Y9PQ27	Cold shock domain-containing protein E1 isoform X1.	Ras GTPase-activating protein 1 isoform X1.	0.652
CSDE1	SRC	A0A2Y9P0H2	A0A2Y9PSD7	Cold shock domain-containing protein E1 isoform X1.	Tyrosine-protein kinase.	0.406
ERAS	PDPK1	A0A2Y9MKI3	A0A2Y9Q4F2	GTPase ERas.	3-phosphoinositide-dependent protein kinase 1 isoform X1.	0.416
ERAS	PRKCD	A0A2Y9MKI3	A0A2Y9NAV7	GTPase ERas.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.445
ERAS	RASA1	A0A2Y9MKI3	A0A2Y9PQ27	GTPase ERas.	Ras GTPase-activating protein 1 isoform X1.	0.679
ERAS	SRC	A0A2Y9MKI3	A0A2Y9PSD7	GTPase ERas.	Tyrosine-protein kinase.	0.410
HRAS	KDR	A0A2Y9MGR2	A0A2Y9MRB1	GTPase HRas isoform X1.	Vascular endothelial growth factor receptor 2 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.516
HRAS	KRAS	A0A2Y9MGR2	A0A2Y9NF08	GTPase HRas isoform X1.	GTPase KRas.	0.940
HRAS	NRAS	A0A2Y9MGR2	A0A2Y9PBA0	GTPase HRas isoform X1.	GTPase NRas.	0.935
HRAS	PDPK1	A0A2Y9MGR2	A0A2Y9Q4F2	GTPase HRas isoform X1.	3-phosphoinositide-dependent protein kinase 1 isoform X1.	0.422
HRAS	PRKCA	A0A2Y9MGR2	A0A2Y9PID1	GTPase HRas isoform X1.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.934
HRAS	PRKCB	A0A2Y9MGR2	A0A2Y9PG08	GTPase HRas isoform X1.	Protein kinase C.	0.925
HRAS	PRKCD	A0A2Y9MGR2	A0A2Y9NAV7	GTPase HRas isoform X1.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.445
HRAS	PRKCZ	A0A2Y9MGR2	A0A2Y9QA49	GTPase HRas isoform X1.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.411
HRAS	RASA1	A0A2Y9MGR2	A0A2Y9PQ27	GTPase HRas isoform X1.	Ras GTPase-activating protein 1 isoform X1.	0.978
HRAS	SRC	A0A2Y9MGR2	A0A2Y9PSD7	GTPase HRas isoform X1.	Tyrosine-protein kinase.	0.965
KDR	HRAS	A0A2Y9MRB1	A0A2Y9MGR2	Vascular endothelial growth factor receptor 2 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	GTPase HRas isoform X1.	0.516
KDR	PLCG1	A0A2Y9MRB1	A0A2Y9PMG8	Vascular endothelial growth factor receptor 2 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.967