STRINGSTRING
NRAS NRAS GRB2 GRB2 FGF1 FGF1 ERAS ERAS HRAS HRAS SHC1 SHC1 FGFR3 FGFR3 LOC111165935 LOC111165935 SOS1 SOS1 FGF9 FGF9 KRAS KRAS CSDE1 CSDE1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NRASGTPase NRas. (189 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (189 aa)
ERASGTPase ERas. (233 aa)
HRASGTPase HRas isoform X1. (189 aa)
SHC1SHC-transforming protein 1 isoform X1. (609 aa)
FGFR3Fibroblast growth factor receptor. (805 aa)
LOC111165935Ras-like protein isoform X1. (285 aa)
SOS1Son of sevenless homolog 1 isoform X1. (1333 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
KRASGTPase KRas. (188 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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