node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FGF1 | FGFR3 | A0A2Y9PQS4 | A0A2Y9LTY2 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Fibroblast growth factor receptor. | 0.983 |
FGF1 | FRS2 | A0A2Y9PQS4 | A0A2Y9MXU5 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Fibroblast growth factor receptor substrate 2. | 0.523 |
FGF1 | GAB1 | A0A2Y9PQS4 | A0A2Y9QCZ2 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | GRB2-associated-binding protein 1 isoform X1. | 0.543 |
FGF1 | GRB2 | A0A2Y9PQS4 | A0A2Y9PJ90 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Growth factor receptor-bound protein 2. | 0.503 |
FGF1 | LOC111187198 | A0A2Y9PQS4 | A0A2Y9QG58 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.415 |
FGF1 | PIK3CA | A0A2Y9PQS4 | A0A2Y9MZW2 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.414 |
FGF1 | PTPN11 | A0A2Y9PQS4 | A0A2Y9QEG1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.421 |
FGF9 | FGFR3 | A0A2Y9N649 | A0A2Y9LTY2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Fibroblast growth factor receptor. | 0.955 |
FGF9 | FRS2 | A0A2Y9N649 | A0A2Y9MXU5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Fibroblast growth factor receptor substrate 2. | 0.629 |
FGF9 | GAB1 | A0A2Y9N649 | A0A2Y9QCZ2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | GRB2-associated-binding protein 1 isoform X1. | 0.408 |
FGF9 | GRB2 | A0A2Y9N649 | A0A2Y9PJ90 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Growth factor receptor-bound protein 2. | 0.491 |
FGF9 | PIK3CA | A0A2Y9N649 | A0A2Y9MZW2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.408 |
FGF9 | PTPN11 | A0A2Y9N649 | A0A2Y9QEG1 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.421 |
FGFR3 | FGF1 | A0A2Y9LTY2 | A0A2Y9PQS4 | Fibroblast growth factor receptor. | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | 0.983 |
FGFR3 | FGF9 | A0A2Y9LTY2 | A0A2Y9N649 | Fibroblast growth factor receptor. | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.955 |
FGFR3 | FRS2 | A0A2Y9LTY2 | A0A2Y9MXU5 | Fibroblast growth factor receptor. | Fibroblast growth factor receptor substrate 2. | 0.801 |
FGFR3 | GAB1 | A0A2Y9LTY2 | A0A2Y9QCZ2 | Fibroblast growth factor receptor. | GRB2-associated-binding protein 1 isoform X1. | 0.944 |
FGFR3 | GRB2 | A0A2Y9LTY2 | A0A2Y9PJ90 | Fibroblast growth factor receptor. | Growth factor receptor-bound protein 2. | 0.960 |
FGFR3 | LOC111187198 | A0A2Y9LTY2 | A0A2Y9QG58 | Fibroblast growth factor receptor. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.513 |
FGFR3 | PIK3CA | A0A2Y9LTY2 | A0A2Y9MZW2 | Fibroblast growth factor receptor. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.893 |