STRINGSTRING
LOC111165935 LOC111165935 FGF18 FGF18 NRAS NRAS GRB2 GRB2 FGF4 FGF4 ERAS ERAS FGF1 FGF1 CSDE1 CSDE1 FGF16 FGF16 FGF23 FGF23 KRAS KRAS FGF6 FGF6 FGF20 FGF20 FGF8 FGF8 FGF9 FGF9 SOS1 SOS1 FGFR4 FGFR4 KLB KLB HRAS HRAS FGF17 FGF17 SHC1 SHC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111165935Ras-like protein isoform X1. (285 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
NRASGTPase NRas. (189 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
ERASGTPase ERas. (233 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (189 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (315 aa)
KRASGTPase KRas. (188 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
SOS1Son of sevenless homolog 1 isoform X1. (1333 aa)
FGFR4Fibroblast growth factor receptor. (801 aa)
KLBLOW QUALITY PROTEIN: beta-klotho. (1046 aa)
HRASGTPase HRas isoform X1. (189 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa)
SHC1SHC-transforming protein 1 isoform X1. (609 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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